@inproceedings{IsmerRotterHeinkeetal.2010,
  author    = {Bruno Ismer and Kirsten-Maria Rotter and Matthias Heinke and Ibrahim Akin and Katharina Kroll and Stephanie Schell-Dieckel and Ulrich Trautwein and Wolfgang Vo{\"s} and Christoph Melzer and Frank Weber and Ralf Peters and Christoph A. Nienaber},
  title     = {Semi-invasive determination of interventricular and intraleftventricular conduction delay in CRT patients},
  series = {Biomedizinische Technik = Biomedical engineering},
  volume    = {55},
  number    = {S1},
  publisher = {Walter de Gruyter},
  address   = {Berlin, Boston},
  issn      = {0013-5585 (Print)},
  doi       = {10.1515/bmt.2010.709},
  pages     = {141 -- 143},
  year      = {2010},
  abstract  = {Using guideline parameters for indication of cardiac resynchronization therapy (CRT), only about two thirds of the patients improve clinically. Unfortunately both, surface ECG and echo are uncertain to predict CRT response. To better characterize cardiac desynchronization in heart failure, interventricular (IVCD) and intra-leftventricular conduction delays (ILVCD) were measured by esophageal left ventricular electrogram (LVE). Recordings in 43 CRT patients (34m, 9f, age: 64.7 ± 9.5yrs) evidenced only weak correlation between IVCD and QRS of 0.53 and between ILVCD and QRS of 0.33. This demonstrated that QRS duration is not a reliable indicator of desynchronization. Therefore, the study resulted into development of LVE feature for a programmer with implant support device. It can be used interoperatively to guide the left ventricular electrode location in order to increase responder rate in CRT.},
  language  = {en}
}