TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed)
A1  - Spangenberg, Bernd
A1  - Seigel, Andrea
A1  - Kempf, Jürgen
A1  - Weinmann, Wolfgang
T1  - Forensic drug analysis by means of diode-array HPTLC using RF and UV library search
T2  - JPC - Journal of Planar Chromatography - Modern TLC
N2  - Diode-array planar chromatography is a versatile tool for identification of pharmaceutical substances In this paper thirty-three compounds with benzodiazepine properties were investigated and the separating conditions for silica gel HPTLC plates and three mobile phases were optimized. Diode-array HPTLC makes it possible to identify all the compounds with high certainty down to a level of 20 ng. An algorithm for spectral recognition which is combined with R F values from the three separation steps into one fit factor is presented. This set of data is unique for each of the compounds investigated and enables unequivocal identification. The method is rapid, inexpensive, and sensitive down to a level of 20 ng mL −1.
KW  - Pharmazie
KW  - Gerichtliche Chemie
KW  - Benzodiazepine
Y1  - 2005
SN  - 0933-4173 (Print)
SS  - 0933-4173 (Print)
SN  - 1789-0993 (Online)
SS  - 1789-0993 (Online)
VL  - 18
IS  - 105
SP  - 336
EP  - 343
PB  - Akadémiai Kiadó
ER  -