TY  - CHAP
U1  - Konferenzveröffentlichung
A1  - Ismer, Bruno
A1  - Rotter, Kirsten-Maria
A1  - Heinke, Matthias
A1  - Akin, Ibrahim
A1  - Kroll, Katharina
A1  - Schell-Dieckel, Stephanie
A1  - Trautwein, Ulrich
A1  - Voß, Wolfgang
A1  - Melzer, Christoph
A1  - Weber, Frank
A1  - Peters, Ralf
A1  - Nienaber, Christoph A.
T1  - Semi-invasive determination of interventricular and intraleftventricular conduction delay in CRT patients
T2  - Biomedizinische Technik = Biomedical engineering
N2  - Using guideline parameters for indication of cardiac resynchronization therapy (CRT), only about two thirds of the patients improve clinically. Unfortunately both, surface ECG and echo are uncertain to predict CRT response. To better characterize cardiac desynchronization in heart failure, interventricular (IVCD) and intra-leftventricular conduction delays (ILVCD) were measured by esophageal left ventricular electrogram (LVE). Recordings in 43 CRT patients (34m, 9f, age: 64.7 ± 9.5yrs) evidenced only weak correlation between IVCD and QRS of 0.53 and between ILVCD and QRS of 0.33. This demonstrated that QRS duration is not a reliable indicator of desynchronization. Therefore, the study resulted into development of LVE feature for a programmer with implant support device. It can be used interoperatively to guide the left ventricular electrode location in order to increase responder rate in CRT.
Y1  - 2010
SN  - 0013-5585 (Print)
SS  - 0013-5585 (Print)
SN  - 1862-278X (Online)
SS  - 1862-278X (Online)
U6  - https://doi.org/10.1515/bmt.2010.709
DO  - https://doi.org/10.1515/bmt.2010.709
VL  - 55
IS  - S1
SP  - 141
EP  - 143
PB  - Walter de Gruyter
CY  - Berlin, Boston
ER  -