TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Klemm, Martin A1 - Kirchner, Thomas A1 - Gröhl, Janek A1 - Cheray, Dominique A1 - Nolden, Marco A1 - Seitel, Alexander A1 - Hoppe, Harald A1 - Maier-Hein, Lena A1 - Franz, Alfred M. T1 - MITK-OpenIGTLink for combining open-source toolkits in real-time computer-assisted interventions JF - Int J Comput Assist Radiol Surg. N2 - PURPOSE: Due to rapid developments in the research areas of medical imaging, medical image processing and robotics, computer-assisted interventions (CAI) are becoming an integral part of modern patient care. From a software engineering point of view, these systems are highly complex and research can benefit greatly from reusing software components. This is supported by a number of open-source toolkits for medical imaging and CAI such as the medical imaging interaction toolkit (MITK), the public software library for ultrasound imaging research (PLUS) and 3D Slicer. An independent inter-toolkit communication such as the open image-guided therapy link (OpenIGTLink) can be used to combine the advantages of these toolkits and enable an easier realization of a clinical CAI workflow. METHODS: MITK-OpenIGTLink is presented as a network interface within MITK that allows easy to use, asynchronous two-way messaging between MITK and clinical devices or other toolkits. Performance and interoperability tests with MITK-OpenIGTLink were carried out considering the whole CAI workflow from data acquisition over processing to visualization. RESULTS: We present how MITK-OpenIGTLink can be applied in different usage scenarios. In performance tests, tracking data were transmitted with a frame rate of up to 1000 Hz and a latency of 2.81 ms. Transmission of images with typical ultrasound (US) and greyscale high-definition (HD) resolutions of [Formula: see text] and [Formula: see text] is possible at up to 512 and 128 Hz, respectively. CONCLUSION: With the integration of OpenIGTLink into MITK, this protocol is now supported by all established open-source toolkits in the field. This eases interoperability between MITK and toolkits such as PLUS or 3D Slicer and facilitates cross-toolkit research collaborations. MITK and its submodule MITK-OpenIGTLink are provided open source under a BSD-style licence ( http://mitk.org ) KW - Open Source KW - Tk Y1 - 2016 U6 - https://doi.org/10.1007/s11548-016-1488-y DO - https://doi.org/10.1007/s11548-016-1488-y VL - 12 IS - 3 SP - 351 EP - 361 ER -