TY - CHAP U1 - Konferenzveröffentlichung A1 - Heinke, Matthias A1 - Ismer, Bruno A1 - Heinke, Tobias A1 - Surber, Ralf A1 - Haltenberger, Anna A1 - Kühnert, Helmut A1 - Eisenträger, Daniela A1 - Lorenz, Martin A1 - Prochnau, Dirk A1 - Dannberg, Gudrun A1 - Figulla, Hans Reiner T1 - Bipolar Transesophageal Left Ventricular Electrocardiography and Directed Electrical Pacing with Cylindrical and Hemispherical Electrodes to Select Patients for Biventricular Pacing T2 - Biomedical Engineering / Biomedizinische Technik N2 - Cardiac resynchronisation therapy (CRT) with biventricular pacing (BV) is an established therapy for heart failure (HF) patients with interventricular conduction delay (IVCD). The aim of the study was to evaluate transesophageal IVCD and left ventricular (LV) pacing with directed electrical pacing field (EPF) in HF patients. Methods: HF patients were analysed with bipolar transesophageal LV electrocardiogram recording and LV pacing with constant voltage stimulus output, 4 ms stimulus duration, distal cylindrical electrode (CE) and seven 6 mm hemispherical electrodes (HE) with 15 mm electrode distance (TO, Dr. Osypka, Rheinfelden, Germany). Results: LV electrocardiogram recording with HE-HE and CE-HE evaluated a mean IVCD of 79.9 ± 36.7 ms. Directed EPF with CE-HE and HE-HE allowed LV VAT (n=12) and LV D00 pacing (n=5) with a mean effective capture output of 97.35 ± 6.64 V. In 15 responders with IVCD of 87 ± 33 ms arterial pulse pressure (PP) increased from 65 ± 24 mmHg to 79 ± 27 mmHg (p < 0.001). EPF was simulated with finite element method. Conclusions: Transesophageal LV electrocardiography and directed EPF pacing with CE and HE allowed the evaluation of IVCD and PP to select patients for BV pacing. Y1 - 2010 SN - 0013-5585 (Print) SS - 0013-5585 (Print) SN - 1862-278X (Online) SS - 1862-278X (Online) U6 - https://doi.org/10.1515/bmt.2010.705 DO - https://doi.org/10.1515/bmt.2010.705 VL - 55 IS - S1 SP - 146 EP - 149 PB - Walter de Gruyter CY - Berlin, Boston ER -