TY  - CHAP
U1  - Konferenzveröffentlichung
A1  - Gebhardt, Daisy
A1  - Schmid, Frauke
A1  - Weber, Frank
A1  - Heinke, Matthias
A1  - Ennker, Ina Carolin
A1  - Melichercik, Juraj
A1  - Ismer, Bruno
T1  - What range of pace-sense-compensation should be provided in biventricular pacing systems for heart failure?
T2  - Biomedical Engineering / Biomedizinische Technik
N2  - In cardiac resynchronization therapy (CRT) for heart failure, individualization of the AV delay is essential to improve hemodynamics and to minimize non-responder rate. In patients in sinus rhythm having additional disposition to bradycardia, optimization is necessary for both situations, atrial sensing and pacing. Therefore, echo-optimization is the goldstandard but time consuming. Unfortunately, it depends on the particular CRT systems parameter set if the resulting individually optimal AV delays can be programmed or not. Some CRT systems provide a set of AV delays for DDD operation combined with a set of the pace-sense-compensation to optimize the AV delay in DDD and VDD operation. The pace-sense-compensation (PSC) can be defined by the difference of implant-related interatrial conduction intervals in DDD and VDD operation measured in the esophageal left atrial electrogram. In a cohort of 96 CRT patients we found mean PSC of 59-35ms ranging between 0-143ms. As a consequence, allowing 10ms tolerance, AVD optimization is completely impossible in one of the two modes, VDD or DDD operation, in 34 (35%) or 5 (5%) patients with implants restricting the PSC range to 60ms or 100ms, respectively. Thus, we propose companies to provide CRT systems with programmable pace-sense- compensation between 0ms and 150ms.
Y1  - 2012
UR  - https://www.researchgate.net/publication/230826826
SN  - 0013-5585 (Print)
SS  - 0013-5585 (Print)
SN  - 1862-278X (Online)
SS  - 1862-278X (Online)
U6  - https://doi.org/10.1515/bmt-2012-4159
DO  - https://doi.org/10.1515/bmt-2012-4159
VL  - 57
IS  - SI-1 Track-Q
SP  - 384
EP  - 385
PB  - Walter de Gruyter
CY  - Berlin, Boston
ER  -