TY  - JOUR
U1  - Wissenschaftlicher Artikel
A1  - Seidenstuecker, Michael
A1  - Schmeichel, Thomas
A1  - Ritschl, Lucas
A1  - Vinke, Johannes
A1  - Schilling, Pia
A1  - Schmal, Hagen
A1  - Bernstein, Anke
T1  - Mechanical Properties of the Composite Material consisting of β-TCP and Alginate-Di-Aldehyde-Gelatin Hydrogel and Its Degradation Behavior
JF  - Materials
N2  - This work aimed to determine the influence of two hydrogels (alginate, alginate-di-aldehyde (ADA)/gelatin) on the mechanical strength of microporous ceramics, which have been loaded with these hydrogels. For this purpose, the compressive strength was determined using a Zwick Z005 universal testing machine. In addition, the degradation behavior according to ISO EN 10993-14 in TRIS buffer pH 5.0 and pH 7.4 over 60 days was determined, and its effects on the compressive strength were investigated. The loading was carried out by means of a flow-chamber. The weight of the samples (manufacturer: Robert Mathys Foundation (RMS) and Curasan) in TRIS solutions pH 5 and pH 7 increased within 4 h (mean 48 ± 32 mg) and then remained constant over the experimental period of 60 days. The determination surface roughness showed a decrease in the value for the ceramics incubated in TRIS compared to the untreated ceramics. In addition, an increase in protein concentration in solution was determined for ADA gelatin-loaded ceramics. The macroporous Curasan ceramic exhibited a maximum failure load of 29 ± 9.0 N, whereas the value for the microporous RMS ceramic was 931 ± 223 N. Filling the RMS ceramic with ADA gelatin increased the maximum failure load to 1114 ± 300 N. The Curasan ceramics were too fragile for loading. The maximum failure load decreased for the RMS ceramics to 686.55 ± 170 N by incubation in TRIS pH 7.4 and 651 ± 287 N at pH 5.0.
KW  - mechanical properties
KW  - degradation behavior
KW  - β-TCP
KW  - ADA-gelatin gels
KW  - fracture strength
Y1  - 2021
UN  - https://nbn-resolving.org/urn:nbn:de:bsz:ofb1-opus4-54040
SN  - 1996-1944
SS  - 1996-1944
U6  - https://doi.org/10.3390/ma14051303
DO  - https://doi.org/10.3390/ma14051303
VL  - 14
IS  - 5
SP  - 1
EP  - 18
S1  - 18
PB  - MDPI
CY  - Basel
ER  -