TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Ehret, Karl A1 - Heinke, Matthias A1 - Hörth, Johannes T1 - Electrode Model and Simulation of Catheter Ablation of Supraventricular Tachycardia T2 - Acta Scientific Medical Sciences N2 - The high frequency (HF) catheter ablation is the gold standard for the therapy of many cardiac tachyarrhythmias, such as atrioventricular node re-entry tachycardia (AVNRT), atrioventricular re-entry tachycardia (AVRT) or atrial flutter (AFL). The aim of the study was to simulate the HF ablation of AVNRT, AVRT, AFL and its heat propagation in reference to the supplied power with different electrode material and electrode size. The modeling and simulation were performed with the thermal and electromagnetic simulation software CST® (Computer Simulation Technology, Darmstadt). The modeling and simulation were carried out using ablation catheters with 4 mm tip electrode and 8 mm tip electrode with different electrode materials. Both electrode types were made of platinum and gold respectively. For the measurement of the heat propagation in the heart tissue, the catheters were integrated in the Offenburg heart rhythm model. The HF ablation procedures were performed with the 4 mm platinum tip electrode, with an application duration of 45 seconds and a power output of 40 watts. The HF ablation of the atrioventricular node slow pathway produced a maximum temperature of 66.33 °C. The Kent bundle HF ablation in the left atrium achieved a maximum temperature of 67.14 °C. The HF ablation of the right atrial isthmus resulted 65.96 °C. The 8 mm distal platinum tip electrode and a power output of 60 watts reached 72.85 °C. The 8 mm distal gold tip electrode and a power output of 60 watt reached 64.66 °C, due to the improved thermal conductivity of gold. Virtual heart and ablation electrode models allow the static and dynamic simulation of HF ablation with different electrode material and electrode size. The 3D simulation of the temperature profile may be used to optimize the AVNRT, AVRT and AFL HF ablation. KW - Catheter Ablation KW - HF Ablation KW - Supraventricular Tachycardia KW - Electrode Model KW - 3d Heart Simulation KW - Catheter Ablation KW - HF Ablation KW - Supraventricular Tachycardia KW - Electrode Model KW - 3d Heart Simulation Y1 - 2018 UR - https://actascientific.com/ASMS/pdf/ASMS-02-0143.pdf VL - 2 IS - 9 SP - 19 EP - 22 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Ismer, Bruno A1 - Härtig, Johannes A1 - Heinke, Matthias A1 - Hörth, Johannes A1 - Melichercik, Juraj T1 - Detection of Adverse Timing in Cardiac Resynchronization T2 - Journal of Atrial Fibrillation KW - Herzschrittmacher Y1 - 2013 UR - http://www.jafib.com/published/published.php?cont=va_issue&abstract=127 IS - Special Issue Venice Arrhythmias SP - 136 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Rotter, Kirsten-Maria A1 - Ismer, Bruno A1 - Heinke, Matthias ED - Lévy, Samuel T1 - Esophageal left ventricular electrogram to measure interventricular and intra-left-ventricular conduction delay in CRT patients T2 - Journal of Interventional Cardiac Electrophysiology Y1 - 2010 UR - http://link.springer.com/journal/10840/27/3#page-2 SN - 1383-875X DO - https://dx.doi.org/10.1007/s10840-010-9483-7 VL - 72 IS - 3 SP - 197 EP - 198 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Ismer, Bruno A1 - Rotter, Kirsten-Maria A1 - Heinke, Matthias T1 - Semi-invasive determination of interventricular and intraleftventricular conduction delay in CRT patients T2 - Biomedizinische Technik = Biomedical engineering Y1 - 2010 UR - http://www.degruyter.com/view/j/bmte.2010.55.issue-s1/bmt.2010.709/bmt.2010.709.xml?rskey=oS6yVL&result=1 SN - 0013-5588 VL - 55 IS - s1 SP - 141 EP - 143 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Heinke, Matthias A1 - Ismer, Bruno A1 - Kühnert, Helmut T1 - Optimal biventricular pacing delay and electrical interventricular conduction delay in cardiac resynchronization therapy T2 - Europace : the European journal of pacing, arrhythmias and cardiac electrophysiology N2 - It is not clear whether cardiac resynchronization therapy (CRT) should only be optimized at rest or whether it is necessary to perform CRT optimization during exercise. Our study aims to answer this question by using an inert gas rebreathing method (Innocor®). Y1 - 2012 UR - http://europace.oxfordjournals.org/content/14/2/249.full?sid=30a8e66e-cb22-45af-9e5c-530f3b71c227 SN - 1099-5129 DO - https://dx.doi.org/10.1093/europace/eur296 VL - 14 IS - 2 SP - 249 EP - 253 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Heinke, Matthias A1 - Ismer, Bruno A1 - Kühnert, Helmut T1 - Transesophageal left ventricular electrogram-recording and temporary pacing to improve patient selection for cardiac resynchronization. T2 - Medical & biological engineering & computing : MBEC ; the journal of the International Federation for Medical and Biological Engineering N2 - Cardiac resynchronization therapy (CRT) with biventricular pacing (BV) is an established therapy for heart failure (HF) patients with inter- and intraventricular conduction delay. The aim of this pilot study was to test the feasibility of both transesophageal measurement of left ventricular (LV) electrical delay and transesophageal LV pacing prior to implantation, to better select patients for CRT. Y1 - 2011 UR - http://link.springer.com/article/10.1007%2Fs11517-011-0767-6 SN - 0140-0118 DO - https://dx.doi.org/10.1007/s11517-011-0767-6 VL - 49 IS - 8 SP - 851 EP - 858 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Kühnert, Helmut A1 - Figulla, Hans Reiner A1 - Ismer, Bruno A1 - Heinke, Matthias T1 - New frontiers of supraventricular tachycardia and atrial flutter evaluation and catheter ablation T2 - Biomedizinische Technik = Biomedical Engineering Y1 - 2012 UR - http://www.degruyter.com/view/j/bmte.2012.57.issue-s1-Q/bmt-2012-4169/bmt-2012-4169.xml?rskey=Hc0wGd&result=1 SN - 0013-5585 VL - 57 IS - Suppl. 1 SP - 371 EP - 374 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Töpfer, Anja A1 - Wehsener, Ingolf A1 - Ismer, Bruno A1 - Kühnert, Helmut A1 - Allmann, Jakob A1 - Eisenträger, Daniela A1 - Figulla, Hans Reiner A1 - Heinke, Matthias T1 - Novel telemetric signal averaging ECG approach to determine electrical atrial and ventricular conduction delays in implantable cardioverter defibrillator patients T2 - Biomedical Engineering / Biomedizinische Technik N2 - Cardiac resynchronization therapy (CRT) with biventricular pacing is an established therapy for heart failure (HF) pa-tients (P) with ventricular desynchronization and reduced left ventricular (LV) ejection fraction. The aim of this study was to evaluate electrical right atrial (RA), left atrial (LA), right ventricular (RV) and LV conduction delay with novel telemetric signal averaging electrocardiography (SAECG) in implantable cardioverter defibrillator (ICD) P to better se-lect P for CRT and to improve hemodynamics in cardiac pacing. Methods: ICD-P (n=8, age 70.8 ± 9.0 years; 2 females, 6 males) with VVI-ICD (n=4), DDD-ICD (n=3) and CRT-ICD (n=1) (Medtronic, Inc., Minneapolis, MN, USA) were analysed with telemetric ECG recording by Medronic program-mer 2090, ECG cable 2090AB, PCSU1000 oscilloscope with Pc-Lab2000 software (Velleman®) and novel National In-truments LabView SAECG software. Results: Electrical RA conduction delay (RACD) was measured between onset and offset of RA deflection in the RAECG. Interatrial conduction delay (IACD) was measured between onset of RA deflection and onset of far-field LA deflection in the RAECG. Interventricular conduction delay (IVCD) was measured between onset of RV deflection in the RVECG and onset of LV deflection in the LVECG. Telemetric SAECG recording was possible in all ICD-P with a mean of 11.7 ± 4.4 SAECG heart beats, 97.6 ± 33.7 ms QRS duration, 81.5 ± 44.6 ms RACD, 62.8 ± 28.4 ms RV con-duction delay, 143.7 ± 71.4 ms right cardiac AV delay, 41.5 ms LA conduction delay, 101.6 ms LV conduction delay, 176.8 ms left cardiac AV delay, 53.6 ms IACD and 93 ms IVCD. Conclusions: Determination of RA, LA, RV and LV conduction delay, IACD, IVCD, right and left cardiac AV delay by telemetric SAECG recording using LabView SAECG technique may be useful parameters of atrial and ventricular desynchronization to improve P selection for CRT and hemodynamics in cardiac pacing. KW - Herzschrittmacher KW - Signaltechnik KW - Telemetrie Y1 - 2012 SN - 0013-5585 DO - https://dx.doi.org/10.1515/bmt-2012-4170 VL - 57 IS - Suppl. 1 SP - 6 EP - 9 PB - Berlin, Boston CY - Berlin, Boston ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Ismer, Bruno A1 - Lorenz, Martin A1 - Straube, Kerstin A1 - Figulla, Hans Reiner A1 - Heinke, Matthias T1 - Signal averaging transesophageal left heart ECG software to evaluate left atrial conduction delay and left ventricular conduction delay in heart failure patients …. T2 - Biomedical Engineering / Biomedizinische Technik Y1 - 2012 UR - http://www.degruyter.com/view/j/bmte.2012.57.issue-s1-I/bmt-2012-4274/bmt-2012-4274.xml?rskey=ybvHry&result=4 SN - 1862-278X DO - https://dx.doi.org/10.1515/bmt-2012-4274 VL - 57 IS - Suppl. 1 ER -