TY  - CHAP
U1  - Konferenzveröffentlichung
A1  - Neidhardt, Jonathan Philipp
A1  - Fronczek, David Norman
A1  - Jahnke, Thomas
A1  - Danner, Timo
A1  - Horstmann, Birger
A1  - Bessler, Wolfgang G.
T1  - A Flexible Framework for Modeling Multiple Solid, Liquid and Gaseous Phases in Batteries and Fuel Cells
T2  - Journal of The Electrochemical Society
N2  - Multi-phase management is crucial for performance and durability of electrochemical cells such as batteries and fuel cells. In this paper we present a generic framework for describing the two-dimensional spatiotemporal evolution of gaseous, liquid and solid phases, as well as their interdependence with interfacial (electro-)chemistry and microstructure in a continuum description. The modeling domain consists of up to seven layers (current collectors, channels, electrodes, separator/membrane), each of which can consist of an arbitrary number of bulk phases (gas, liquid, solid) and connecting interfaces (two-phase or multi-phase boundaries). Bulk and interfacial chemistry is described using global or elementary kinetic reactions. Multi-phase management is coupled to chemistry and to mass and charge transport within bulk phases. The functionality and flexibility of this framework is demonstrated using four application areas in the context of post-lithium-ion batteries and fuel cells, that is, lithium-sulfur (Li-S) cells, lithium-oxygen (Li-O) cells, solid oxide fuel cells (SOFC) and polymer electrolyte membrane fuel cells (PEFC). The results are compared to models available in literature and properties of the generic framework are discussed.
KW  - Brennstoffzelle
KW  - Batterie
KW  - Modell
KW  - Rahmen
Y1  - 2012
UR  - https://elib.dlr.de/76228/1/Neidhardt_et_al_2012_MODVAL9.pdf
SN  - 0013-4651
SS  - 0013-4651
U6  - https://doi.org/10.1149/2.023209jes
DO  - https://doi.org/10.1149/2.023209jes
N1  - 9th Symposium on Fuel Cell and Battery Modeling and Experimental Validation (ModVal 9), Campus Sursee, Switzerland, April 2-4, 2012
VL  - 159
IS  - 9
SP  - A1528
EP  - A1542
ER  - 
TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed)
A1  - Mensonides-Harsema, Marguérite M.
A1  - Otte, Andreas
T1  - European regulatory framework on the use and development of pharmaceuticals and radiopharmaceuticals for pediatrics
JF  - Hellenic Journal of Nuclear Medicine
N2  - A survey in 2000 revealed that only about 30% of the prescriptions in the European pediatric population were on the basis of evidence-based medicine (EbM). Less for radiopharmaceuticals and principally for diagnostics, radiologists throughout Europe are referred to the pediatric guidelines of the European Association of Nuclear Medicine (EANM), as none of the frequently used tracers have been evaluated in clinical trials in the different pediatric subgroups. Following a resolution to address the lack of EbM in children, the European Commission published the Pediatric Regulation EC 1901/2006 and its amendment EC 1902/2006, effective from 2007. This regulation foresees the development of evidence-based medicine in the pediatric population. This is effected through a set of principles like the mandatory pediatric investigation plan (PIP) to be included with the market authorization application (MAA), and the pediatric use market authorization (PUMA) for off-patent pharmaceuticals, and to a very small part radiopharmaceuticals with funding possibilities for pediatric-specific research through the 7th Framework Programme (7FP) of the European Union.
KW  - Kinderheilkunde
KW  - Pharmazie
KW  - Europa
KW  - Rahmen
Y1  - 2011
UR  - https://www.nuclmed.gr/wp/wp-content/uploads/2017/03/14-1.pdf
SN  - 1790-5427
SS  - 1790-5427
PM  - 21512665
VL  - 14
IS  - 1
SP  - 43
EP  - 48
ER  -