TY  - JOUR
U1  - Zeitschriftenartikel, nicht wissenschaftlich
A1  - Ismer, Bruno
A1  - Kroll, Katharina
A1  - Rotter, Kirsten-Maria
A1  - Langefeld, Matthias
A1  - Akin, Ibrahim
A1  - Schell-Dieckel, Stephanie
A1  - Trautwein, Ulrich
A1  - Heinke, Matthias
A1  - Melzer, Christoph
A1  - Weber, Frank
T1  - Kann die Effektivität einer Resynchronisationstherapie der Herzschwäche gesteigert werden?
N2  - Die kardiale Resynchronisationstherapie ist ein großer Segen für viele Patienten mit einer Herzschwäche, die auf einen krankhaften Verlust der synchronen Kontraktion beider Herzkammern zurückzuführen ist. Warum einige von ihnen jedoch nicht darauf ansprechen, wird gegenwärtig erforscht. Als eine neue Methode mit dem Ziel der Effektivitätssteigerung dieser Therapie mit elektronischen Implantaten demonstrieren wir die Nutzbarkeit von durch eine Schluckelektrode aus der Speiseröhre abgeleiteten Elektrokardiogrammen.
KW  - Kardiale Resynchronisationstherapie
KW  - Herzinsuffizienz
Y1  - 2011
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bsz:ofb1-opus-1044
UN  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bsz:ofb1-opus-1044
VL  - 2011
SP  - 29
EP  - 32
ER  - 
TY  - JOUR
U1  - Zeitschriftenartikel, nicht wissenschaftlich
A1  - Otte, Andreas
A1  - Ismer, Bruno
A1  - Heinke, Matthias
A1  - Melichercik, Juraj
T1  - Nuclear imaging and semi-invasive electrocardiography in CRT
JF  - Beiträge aus Forschung & Technik
N2  - Cardiac resynchronisation therapy (CRT) is a promising treatment option in patients with chronic heart failure. In this article the roles of semi-invasive esophageal left-heart electrocardiography and functional cardiac nuclear imaging in the field of CRT are highlighted, as the combination of both could be a favourable diagnostic approach in special cardiac situations. Also original esophageal left heart electrogram data of exemplary CRT patients is presented.
KW  - Kardiale Resynchronisationstherapie
KW  - cardiac resynchronisation therapy
KW  - CRT
KW  - nuclear imaging
KW  - chronic heart failure
KW  - semi-invasive electrocardiography
Y1  - 2012
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bsz:ofb1-opus-1482
UN  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bsz:ofb1-opus-1482
SN  - 1866-9352
SS  - 1866-9352
VL  - 2012
SP  - 33
EP  - 34
ER  - 
TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed)
A1  - Heinke, Matthias
A1  - Ismer, Bruno
A1  - Kühnert, Helmut
A1  - Dannberg, Gudrun
A1  - Figulla, Hans Reiner
T1  - Prä- und postoperative Bestimmung des elektrischen linksventrikulären Delays bei kardialen Resynchronisationstherapie Respondern und Nonrespondern
T2  - Clinical Research in Cardiology Supplements
KW  - Kardiale Resynchronisationstherapie
Y1  - 2013
SN  - 1861-0706
SS  - 1861-0706
U6  - https://dx.doi.org/10.1007/s00392-013-1100-1
DO  - https://dx.doi.org/10.1007/s00392-013-1100-1
VL  - 102
IS  - 1
SP  - 1635
ER  - 
TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed)
A1  - Heinke, Matthias
A1  - Kühnert, Helmut
A1  - Dannberg, Gudrun
T1  - Electrical interventricular delay to left ventricular delay ratio in atrial fibrillation cardiac resynchronization therapy responder and non-responder
JF  - EP Europace
N2  - Background: Cardiac resynchronization therapy (CRT) is an established therapy for heart failure (HF) patients (P) with reduced left ventricular (LV) ejection fraction and electrical interventricular desynchronization, but not all P improved clinically. The aim of the study was to evaluate electrical interventricular delay (IVD) to LV delay (LVD) ratio in atrial fibrillation (AF) CRT responder (R) and non-responder (NR).

Methods: AF P (n = 18, age 60.6 ± 11.4 years, 1 female, 17 males) with HF New York Heart Association (NYHA) class 3.0 ± 0.2, 25.3 ± 5.9 % LV ejection fraction and 157.8 ± 24.4 ms QRS duration (QRSD) were measured by surface ECG and focused transesophageal bipolar LV ECG before implantation of CRT pacemaker (n = 2) or CRT defibrillator (n = 16). IVD was measured between onset of QRS in the surface ECG and onset of LV signal in the LV ECG. LVD was measured between onset and offset of LV signal in the LV ECG.

Results: Electrical ventricular desynchronization in AF CRT P were 61.9 ± 26.9ms IVD, 80.6 ± 24.3ms LVD, 0.85 ± 0.41 IVD-LVD-ratio (Figure), 3.12 ± 1.89 QRSD-IVD-ratio and 2.07 ± 0.47 QRSD-LVD-ratio. There were 72.2 % AF CRT R (n = 13) with 64.2 ± 24.6ms IVD and 77.8 ± 21.6ms LVD with Pearson correlation to 0.89 ± 0.39 IVD-LVD-ratio (r = 0.87, P < 0.01; r = -0.69, P < 0.01), 2.82 ± 1.32 QRSD-IVD-ratio (r = -0.76, P < 0.01; r = 0.67, P = 0.011) and 2.13 ± 0.46 QRSD-LVD-ratio (r = 0.57, P = 0.041; r = -0.85, P < 0.01). There were 27.8% AF CRT NR (n = 5) with 56.0 ± 34.5ms IVD and 87.8 ± 31.9ms LVD without correlation to 0.74 ± 0.48 IVD-LVD-ratio, 3.88 ± 2.98 QRSD-IVD-ratio and 1.90 ± 0.48 QRSD-LVD-ratio. During 15.3 ± 13.1 month CRT follow-up, the AF CRT R NYHA class improved from 3.0 ± 0.2 to 2.2 ± 0.3 (P < 0.001). During 18.8 ± 20.7 month CRT follow-up, the AF CRT NR NYHA class not improved from 3 to 3.3 ± 0.97.
KW  - Kardiale Resynchronisationstherapie
Y1  - 2016
U6  - https://dx.doi.org/10.1093/europace/18.suppl_1.i164a
DO  - https://dx.doi.org/10.1093/europace/18.suppl_1.i164a
VL  - 18
IS  - Suppl. 1
ER  -