TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Spangenberg, Bernd A1 - Milz, Barbara T1 - Dünnschichtchromatographie: Schnelle Analyse vor Ort T2 - CITplus - Das Praxismagazin für Verfahrens- und Chemieingenieure N2 - Die Weltwirtschaftskrise 2008 hat mit ihrer zeitweisen Verknappung von Acetonitril eindringlich gezeigt, dass man nicht nur auf eine einzige chromatographische Methode setzten sollte. Genau dies wird aber im Augenblick getan, denn Industrie und Forschung setzen mehrheitlich auf die High Performance Liquid Chromatography (HPLC) als die Trennmethode ihrer Wahl. Für viele Anwendungen in der Pharmazie, in der Umweltanalytik, der Lebensmittelanalytik, aber auch in der Inprozesskontrolle gibt es mit der Dünnschichtchromatografie eine Alternative. Y1 - 2012 UR - https://www.chemanager-online.com/themen/mechanische-verfahrenstechnik/duennschichtchromatographie-schnelle-analyse-vor-ort SN - 1436-2597 SS - 1436-2597 VL - 15 IS - 7-8 SP - 43 EP - 44 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Milz, Barbara A1 - Bin Idros, Idzaid A1 - Spangenberg, Bernd T1 - Limits of quantification of some neonicotinoid insecticides measured by thin-layer chromatography JF - Journal of Liquid Chromatography & Related Technologies N2 - A simple method to quantify the neonicotinoid insecticides nitenpyram, thiamethoxam, acetamiprid, imidacloprid, thiacloprid and clothianidin directly on an HPTLC-plate is presented. As stationary phase silica gel 60 RP-18WF254 s plates were used and a mixture of methyl-t-butyl ether, 2-butanone, NH3 (25%) (5 + 2+0.1, v/v) was used as solvent. All neonicotinoid insecticides show light absorptions below 300 nm. The calculated limits of quantification (LOQ) by UV-detection are in the range from 12 ng to 26 ng on plate depending on the different insecticides.Nitenpyram can be stained using fast blue salt B, forming red zones. The observed LOQ is 25 ng on plate. Acetamiprid can be specifically stained using phenylglyoxylic acid forming a yellow/green fluorescent compound. The LOQ is 52 ng per spot.The compounds thiamethoxam, acetamiprid, thiacloprid and clothianidin can be transformed into blue fluorescing zones, using a relatively new staining solution. This consists of tetraphenylborate and HCl. This is the first publication mentioning that neonicotinoids undergo this reaction. The calculated limits of quantification are in the range from 10 ng to 27 ng on plate.A simple pre-treatment procedure using an acetonitrile extraction and a Chromabond SiOH clean up procedure leads to overall LOQs for bee samples of 48 to 108 µg/Kg. The method can be used to measure neonicotinoid contaminations of bees. KW - Dünnschichtchromatographie KW - Insektizid KW - Belastung KW - Biene Y1 - 2012 SN - 1082-6076 SS - 1082-6076 U6 - https://dx.doi.org/10.1080/10826076.2012.676842 DO - https://dx.doi.org/10.1080/10826076.2012.676842 VL - 35 IS - 10 SP - 1404 EP - 1414 PB - Taylor & Francis ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Milz, Barbara A1 - Spangenberg, Bernd T1 - 2D-Thin-Layer Chromatography (2D-TLC) Flash Test of 17α-Ethinylestradiol and related Steroids detected by Fluorescence Densitometry JF - Journal of liquid chromatography & related technologies KW - Dünnschichtchromatographie Y1 - 2013 SN - 1082-6076 SS - 1082-6076 VL - 36 IS - 17 SP - 2378 EP - 2386 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Milz, Barbara A1 - Spangenberg, Bernd T1 - A Validated Quantification of Benzocaine in Lozenges Using TLC and a Flatbed Scanner JF - Chromatographia KW - Dünnschichtchromatographie KW - Benzocain Y1 - 2013 SN - 0009-5893 SS - 0009-5893 U6 - https://dx.doi.org/10.1007/s10337-013-2436-4 DO - https://dx.doi.org/10.1007/s10337-013-2436-4 VL - 76 IS - 19-20 Special Issue/2013 SP - 1307 EP - 1313 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Seigel, Andrea A1 - Milz, Barbara A1 - Spangenberg, Bernd T1 - Quantification of Parabens by Diode-Array Thin-Layer Chromatography Coupled with a Vibrio fischeri Bioluminescence Assay JF - Journal of Planar Chromatography KW - Dünnschichtchromatographie KW - Biolumineszenz Y1 - 2013 SN - 0933-4173 SS - 0933-4173 VL - 26 IS - 2/2013 SP - 119 EP - 124 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Spangenberg, Bernd A1 - Milz, Barbara T1 - Schnelle Analyse vor Ort : Moderne Auswertung in der Dünnschichtchromatographie T2 - GIT : Labor-Fachzeitschrift N2 - Die Weltwirtschaftskrise 2008 hat mit ihrer zeitweisen Verknappung von Acetonitril eindringlich gezeigt, dass man nicht nur auf eine einzige chromatographische Methode setzten sollte. Genau dies wird aber im Augenblick getan, denn Industrie und Forschung setzen mehrheitlich auf die High Performance Liquid Chromatography (HPLC) als die Trennmethode ihrer Wahl. Für viele Anwendungen in der Pharmazie, in der Umweltanalytik, der Lebensmittelanalytik, aber auch in der Inprozesskontrolle gibt es mit der Dünnschichtchromatografie eine Alternative. KW - Kardiale Resynchronisationstherapie Y1 - 2013 SN - 0016-3538 SS - 0016-3538 VL - 57 IS - 8 SP - 484 EP - 485 PB - GIT Verlag ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Milz, Barbara A1 - Spangenberg, Bernd T1 - Grafted 2D-Thin Layer Chromatography (2D-TLC) of 17α-Ethinylestradiol detected by Bio-directed Analysis JF - Journal of Liquid Chromatography & Related Technologies N2 - We present a two dimensional (2D) planar chromatographic separation of estrogenic active compounds on RP-18 (Merck, 1.05559) and silica gel (Merck, 1.05721) phase. A mixture of 13 substances was separated using a solvent mix consisting of methanol–acetonitrile–water (2 + 2 + 1, v/v/v) on RP-18 phase in the first direction and cyclohexane–butylacetate–methanol (8 + 6 + 1, v/v/v) in the second direction on silica gel plate. Both developments were carried out over a distance of 70 mm. We used the grafted method to combine both plates in a 2D-separation. This 2D-separation method can be used to quantify 17α-ethinylestradiol (EE2) in an effect-directed analysis using the yeast strain Saccharomyces cerevisiae BJ3505. The test strain (according to McDonnell) contains the estrogen receptor. Its activation by estrogen active compounds is measured by inducting the reporter gene lacZ that encodes the enzyme ß-galactosidase. This enzyme activity is determined on plate by using the fluorescent substrate MUG (4-methylumbelliferyl ß-D-galactopyranoside). KW - Dünnschichtchromatographie KW - Polymerisation KW - Ethinylestradiol KW - Analyse Y1 - 2014 SN - 1082-6076 SS - 1082-6076 U6 - https://dx.doi.org/10.1080/10826076.2014.907109 DO - https://dx.doi.org/10.1080/10826076.2014.907109 VL - 37 IS - 20 SP - 2872 EP - 2881 PB - Taylor & Francis ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Lotz, Andreas A1 - Milz, Barbara A1 - Spangenberg, Bernd T1 - A New and Sensitive TLC Method to Measure Trans-Resveratrol in Red Wine JF - Journal of liquid chromatography & related technologies KW - Dünnschichtchromatographie KW - Resveratrol Y1 - 2015 SN - 1082-6076 SS - 1082-6076 U6 - https://dx.doi.org/10.1080/10826076.2015.1028288 DO - https://dx.doi.org/10.1080/10826076.2015.1028288 VL - 38 IS - 11 Special Issue: Thin-Layer Chromatography SP - 1104 EP - 1108 ER - TY - CHAP U1 - Konferenzveröffentlichung A1 - Lotz, Andreas A1 - Milz, Barbara A1 - Spangenberg, Bernd T1 - Chemiluminescence and TLC : A successful combination T2 - 21th International Symposium on Separation Science, June 30th - July 3rd, 2015 in Ljubljana, Slovenia: Book of Abstracts KW - Lumineszenz KW - Dünnschichtchromatographie Y1 - 2015 SP - 37 ER - TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed) A1 - Humpert, Désirée A1 - Milz, Barbara A1 - Lotz, Andreas A1 - Spangenberg, Bernd T1 - Thin-Layer Chromatographic Separation and In Situ Chemiluminescence of Phenolic Compounds KW - Dünnschichtchromatographie KW - Lumineszenz KW - Phenol Y1 - 2016 U6 - https://dx.doi.org/10.1556/1006.2016.29.4.11 DO - https://dx.doi.org/10.1556/1006.2016.29.4.11 SP - 318 EP - 322 ER -