TY  - CHAP
U1  - Konferenzveröffentlichung
A1  - Lorenz, Martin
A1  - Ismer, Bruno
A1  - Straube, Kerstin
A1  - Figulla, Hans Reiner
A1  - Heinke, Matthias
T1  - Signal averaging transesophageal left heart ECG software to evaluate left atrial conduction delay and left ventricular conduction delay in heart failure patients with dilated and ischaemic cardiomyopathy
T2  - Biomedical Engineering / Biomedizinische Technik
N2  - Cardiac resynchronization therapy with biventricular pacing is an established therapy for heart failure patients with electrical left ventricular desynchronization. The aim of this study was to evaluate left atrial conduction delay, intra left atrial conduction delay, left ventricular conduction delay and intra left ventricular conduction delay in heart failure patients using novel signal averaging transesophageal left heart ECG software.
Methods: 8 heart failure patients with dilated cardiomyopathy (DCM), age 68 ± 9 years, New York Heart Association (NYHA) class 2.9 ± 0.2, 24.8 ± 6.7 % left ventricular ejection fraction, 188.8 ± 15.5 ms QRS duration and 8 heart failure patients with ischaemic cardiomyopathy (ICM), age 67 ± 8 years, NYHA class 2.9 ± 0.3, 32.5 ± 7.4 % left ventricular ejection fraction and 167.6 ± 19.4 ms QRS duration were analysed with transesophageal and transthoracic ECG by Bard LabDuo EP system and novel National Intruments LabView signal averaging ECG software.
Results: The electrical left atrial conduction delay was 71.3 ± 17.6 ms in ICM versus 72.3 ± 12.4 ms in DCM, intra left atrial conduction delay 66.8 ± 8.6 ms in ICM versus 63.4 ± 10.9 ms in DCM and left cardiac AV delay 180.5 ± 32.6 ms in ICM versus 152.4 ± 30.4 ms in DCM. The electrical left ventricular conduction delay was 40.9 ± 7.5 ms in ICM versus 42.6 ± 17 ms in DCM and intra left ventricular conduction delay 105.6 ± 19.3 ms in ICM versus 128.3 ± 24.1 ms in DCM.
Conclusions: Left heart signal averaging ECG can be utilized to analyse left atrial conduction delay, intra left atrial conduction delay, left ventricular conduction delay and intra left ventricular conduction delay to improve patient selection for cardiac resynchronization therapy.
KW  - Herzmuskelkrankheit
KW  - Elektrokardiogramm
KW  - Überwachung
KW  - Signaltechnik
Y1  - 2012
SN  - 0013-5585 (Print)
SS  - 0013-5585 (Print)
SN  - 1862-278X (Online)
SS  - 1862-278X (Online)
U6  - https://dx.doi.org/10.1515/bmt-2012-4274
DO  - https://dx.doi.org/10.1515/bmt-2012-4274
N1  - Proceedings BMT 2012, 46. DGBMT Jahrestagung, Jena - Track I. Clinical Engineering, 16.-19.09.2012
VL  - 57
IS  - SI-1 Track-I
SP  - 4
S1  - 4
PB  - Walter de Gruyter
CY  - Berlin, Boston
ER  - 
TY  - CHAP
U1  - Konferenzveröffentlichung
A1  - Töpfer, Anja
A1  - Wehsener, Ingolf
A1  - Ismer, Bruno
A1  - Kühnert, Helmut
A1  - Allmann, Jakob
A1  - Eisenträger, Daniela
A1  - Figulla, Hans Reiner
A1  - Heinke, Matthias
T1  - Novel telemetric signal averaging ECG approach to determine electrical atrial and ventricular conduction delays in implantable cardioverter defibrillator patients
T2  - Biomedical Engineering / Biomedizinische Technik
N2  - Cardiac resynchronization therapy (CRT) with biventricular pacing is an established therapy for heart failure (HF) patients (P) with ventricular desynchronization and reduced left ventricular (LV) ejection fraction. The aim of this study was to evaluate electrical right atrial (RA), left atrial (LA), right ventricular (RV) and LV conduction delay with novel telemetric signal averaging electrocardiography (SAECG) in implantable cardioverter defibrillator (ICD) P to better select P for CRT and to improve hemodynamics in cardiac pacing. 
Methods: ICD-P (n=8, age 70.8 ± 9.0 years; 2 females, 6 males) with VVI-ICD (n=4), DDD-ICD (n=3) and CRT-ICD (n=1) (Medtronic, Inc., Minneapolis, MN, USA) were analysed with telemetric ECG recording by Medronic programmer 2090, ECG cable 2090AB, PCSU1000 oscilloscope with Pc-Lab2000 software (Velleman®) and novel National Intruments LabView SAECG software. 
Results: Electrical RA conduction delay (RACD) was measured between onset and offset of RA deflection in the RAECG. Interatrial conduction delay (IACD) was measured between onset of RA deflection and onset of far-field LA deflection in the RAECG. Interventricular conduction delay (IVCD) was measured between onset of RV deflection in the RVECG and onset of LV deflection in the LVECG. Telemetric SAECG recording was possible in all ICD-P with a mean of 11.7 ± 4.4 SAECG heart beats, 97.6 ± 33.7 ms QRS duration, 81.5 ± 44.6 ms RACD, 62.8 ± 28.4 ms RV conduction delay, 143.7 ± 71.4 ms right cardiac AV delay, 41.5 ms LA conduction delay, 101.6 ms LV conduction delay, 176.8 ms left cardiac AV delay, 53.6 ms IACD and 93 ms IVCD. 
Conclusions: Determination of RA, LA, RV and LV conduction delay, IACD, IVCD, right and left cardiac AV delay by telemetric SAECG recording using LabView SAECG technique may be useful parameters of atrial and ventricular desynchronization to improve P selection for CRT and hemodynamics in cardiac pacing.
KW  - Herzschrittmacher
KW  - Signaltechnik
KW  - Telemetrie
Y1  - 2012
SN  - 0013-5585 (Print)
SS  - 0013-5585 (Print)
SN  - 1862-278X (Online)
SS  - 1862-278X (Online)
U6  - https://dx.doi.org/10.1515/bmt-2012-4170
DO  - https://dx.doi.org/10.1515/bmt-2012-4170
N1  - Proceedings BMT 2012, 46. DGBMT Jahrestagung, Jena - Track F. Biosignal Processing, 16.-19.09.2012
VL  - 57
IS  - SI-1 Track-F
SP  - 6
EP  - 9
S1  - 4
PB  - Walter de Gruyter
CY  - Berlin, Boston
ER  -