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Heart rhythm model for the simulation of electric fields in trans esophageal atrial pacing and cardiac resynchronization therapy

  • Abstract: Electric field of biventricular (BV) pacing, left ventricular (LV) electrode position and electrical interventricular desynchronization are important parameters for successful cardiac resynchronization therapy (CRT) in patients with heart failure, sinus rhythm and reduced LV ejection fraction. The aim of the study was to evaluate electric pacing field of transesophageal left atrial (LA)Abstract: Electric field of biventricular (BV) pacing, left ventricular (LV) electrode position and electrical interventricular desynchronization are important parameters for successful cardiac resynchronization therapy (CRT) in patients with heart failure, sinus rhythm and reduced LV ejection fraction. The aim of the study was to evaluate electric pacing field of transesophageal left atrial (LA) pacing and BV pacing with 3D heart rhythm simulation. Bipolar right atrial (RA), right ventricular (RV), LV electrodes and multipolar hemispherical esophageal LA electrodes were modeled with CST (Computer Simulation Technology, Darmstadt). Electric pacing field were simulated with bipolar RA and RV pacing with Solid S (Biotronik) electrode, bipolar LV pacing with Attain 4194 (Medtronic) electrode and bipolar LA pacing with TO8 (Osypka) esophageal electrode. 3D heart rhythm model with esophagus allowed electric pacing field simulation of 4-chamber pacing with bipolar intracardiac RA, RV, LV pacing and bipolar transesophageal LA pacing. The pacing amplitudes were 3V RA pacing amplitude, 50V LA pacing amplitude, 1.5V RV pacing amplitude and 3V LV pacing amplitude with 0.5ms pacing pulse duration. The atrioventricular delay between RA pacing and BV pacing was 140ms atrioventricular pacing delay and simultaneous RV and LV pacing. Electric pacing fields were simulated during the different pacing modes AAI, VVI, DDD and DDD0V. The intracardiac far-field pacing potentials were evaluated with intracardiac electrodes and a distance of 1mm from the electrodes with RA electrode 1.104V, RV electrode 0.703V and LV electrode 1.32V. The transesophageal far-field pacing potential was evaluated with transesophageal electrode and a distance of 10mm from the elelctrode with LA electrode 6.076V. Heart rhythm model simulation with esophagus allows evaluation of electric pacing fields in AAI, VVI, DDD, DDD0V and DDD0D pacing modes. Electric pacing field of RA, RV and LV pacing in combination with LA pacing may additional useful pacing mode in CRT non-responders.show moreshow less

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Metadaten
Document Type:Article (reviewed)
Zitierlink: https://opus.hs-offenburg.de/2971
Bibliografische Angaben
Title (English):Heart rhythm model for the simulation of electric fields in trans esophageal atrial pacing and cardiac resynchronization therapy
Author:Kerem Göküs, Matthias HeinkeStaff MemberORCiDGND, Johannes HörthStaff MemberGND
Year of Publication:2018
Publisher:De Gruyter
First Page:443
Last Page:445
Parent Title (English):Current Directions in Biomedical Engineering
Volume:4
Issue:1
ISSN:2364-5504
DOI:https://doi.org/10.1515/cdbme-2018-0105
URL:https://www.degruyter.com/view/j/cdbme.2018.4.issue-1/cdbme-2018-0105/cdbme-2018-0105.xml?format=INT
Language:English
Inhaltliche Informationen
Institutes:Fakultät Elektrotechnik und Informationstechnik (E+I) (bis 03/2019)
Institutes:Bibliografie
DDC classes:600 Technik, Medizin, angewandte Wissenschaften
GND Keyword:3D modeling; biventricular stimulation; cardiac resynchronization therapy; computer simulation technology; transesophageal atrial pacing
Tag:3D modeling; biventricular stimulation; cardiac resynchronization therapy; computer simulation technology; transesophageal atrial pacing
Formale Angaben
Open Access: Open Access 
Licence (German):License LogoUrheberrechtlich geschützt