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What range of pace-sense-compensation should be provided in biventricular pacing systems for heart failure?

  • In cardiac resynchronization therapy (CRT) for heart failure, individualization of the AV delay is essential to improve hemodynamics and to minimize non-responder rate. In patients in sinus rhythm having additional disposition to bradycardia, optimization is necessary for both situations, atrial sensing and pacing. Therefore, echo-optimization is the goldstandard but time consuming. Unfortunately,In cardiac resynchronization therapy (CRT) for heart failure, individualization of the AV delay is essential to improve hemodynamics and to minimize non-responder rate. In patients in sinus rhythm having additional disposition to bradycardia, optimization is necessary for both situations, atrial sensing and pacing. Therefore, echo-optimization is the goldstandard but time consuming. Unfortunately, it depends on the particular CRT systems parameter set if the resulting individually optimal AV delays can be programmed or not. Some CRT systems provide a set of AV delays for DDD operation combined with a set of the pace-sense-compensation to optimize the AV delay in DDD and VDD operation. The pace-sense-compensation (PSC) can be defined by the difference of implant-related interatrial conduction intervals in DDD and VDD operation measured in the esophageal left atrial electrogram. In a cohort of 96 CRT patients we found mean PSC of 59-35ms ranging between 0-143ms. As a consequence, allowing 10ms tolerance, AVD optimization is completely impossible in one of the two modes, VDD or DDD operation, in 34 (35%) or 5 (5%) patients with implants restricting the PSC range to 60ms or 100ms, respectively. Thus, we propose companies to provide CRT systems with programmable pace-sense- compensation between 0ms and 150ms.show moreshow less

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Metadaten
Document Type:Conference Proceeding
Conference Type:Konferenz-Abstract
Zitierlink: https://opus.hs-offenburg.de/728
Bibliografische Angaben
Title (English):What range of pace-sense-compensation should be provided in biventricular pacing systems for heart failure?
Conference:BMT 2012: Annual Conference of the German Society for Biomedical Engineering / DGBMT Jahrestagung (45. : 16.-19. September 2012 : Jena)
Author:Daisy GebhardtStaff Member, Frauke SchmidGND, Frank Weber, Matthias HeinkeStaff MemberORCiDGND, Ina Carolin Ennker, Juraj MelichercikStaff Member, Bruno IsmerStaff MemberGND
Date of Publication (online):2012/09/06
Place of publication:Berlin, Boston
Publisher:Walter de Gruyter
First Page:384
Last Page:385
Parent Title (Multiple languages):Biomedical Engineering / Biomedizinische Technik
Volume:57
Issue:SI-1 Track-Q
ISSN:0013-5585 (Print)
ISSN:1862-278X (Online)
DOI:https://doi.org/10.1515/bmt-2012-4159
URL:https://www.researchgate.net/publication/230826826
Language:English
Inhaltliche Informationen
Institutes:Fakultät Maschinenbau und Verfahrenstechnik (M+V)
Institutes:Bibliografie
Formale Angaben
Open Access: Open Access 
Licence (German):License LogoUrheberrechtlich geschützt