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Simulation of Electrical Fields in Cardiac Resynchronization Therapy and Temperature Spread in HF Ablation

  • Background: The electrical field (E-field) of the biventricular (BV) stimulation is important for the success of cardiac resynchronization therapy (CRT) in patients with cardiac insufficiency and widened QRS complex. The 3D modeling allows the simulation of CRT and high frequency (HF) ablation. Purpose: The aim of the study was to model different pacing and ablation electrodes and to integrateBackground: The electrical field (E-field) of the biventricular (BV) stimulation is important for the success of cardiac resynchronization therapy (CRT) in patients with cardiac insufficiency and widened QRS complex. The 3D modeling allows the simulation of CRT and high frequency (HF) ablation. Purpose: The aim of the study was to model different pacing and ablation electrodes and to integrate them into a heart model for the static and dynamic simulation of atrial and BV stimulation and high frequency (HF) ablation in atrial fibrillation (AF). Methods: The modeling and simulation was carried out using the electromagnetic simulation software CST (CST Darmstadt). Five multipolar left ventricular (LV) electrodes, one epicardial LV electrode, four bipolar right atrial (RA) electrodes, two right ventricular (RV) electrodes and one HF ablation catheter were modeled. Selected electrodes were integrated into the Offenburg heart rhythm model for the electrical field simulation. The simulation of an AV node ablation at CRT was performed with RA, RV and LV electrodes and integrated ablation catheter with an 8 mm gold tip. Results: The right atrial stimulation was performed with an amplitude of 1.5 V with a pulse width of 0.5. The far-field potentials generated by the atrial stimulation were perceived by the right and left ventricular electrode. The far-field potential at a distance of 1 mm from the right ventricular electrode tip was 36.1 mV. The far-field potential at a distance of 1 mm from the left ventricular electrode tip was measured with 37.1 mV. The RV and LV stimulation were performed simultaneously at amplitude of 3 V at the LV electrode and 1 V at the RV electrode with a pulse width of 0.5 ms each. The far-field potentials generated by the BV stimulations could be perceived by the RA electrode. The far-field potential at the RA electrode tip was 32.86 mV. AV node ablation was simulated with an applied power of 5 W at 420 kHz and 10 W at 500 kHz at the distal 8 mm ablation electrode. Conclusions: Virtual heart and electrode models as well as the simulations of electrical fields and temperature profiles allow the static and dynamic simulation of atrial synchronous BV stimulation and HF ablation at AF. The 3D simulation of the electrical field and temperature profile may be used to optimize the CRT and AF ablation.show moreshow less

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Metadaten
Author:Matthias Heinke, Reinhard Echle, Johannes Hörth, Martin Krämer
Year of Publication:2017
Date of first Publication:2017/12/23
Language:English
GND Keyword:CRT; CST; HF-Ablation
Tag:CRT; CST; HF-Ablation
Parent Title (English):SAJ Biotechnology
Volume:Scholarena Journal of Biotechnology
Issue:Volume 4, Issue 1
ISSN:ISSN: 2375-6713
First Page:1
Last Page:6
Document Type:Article (reviewed)
Institutes:Hochschule Offenburg / Bibliografie
Acces Right:Frei zugänglich
Release Date:2018/01/24
Licence (German):License LogoEs gilt das UrhG
URL:http://www.scholarena.com/journals/saj-biotechnology/articles.php?volume=3&issue=1
DOI:https://doi.org/http://article.scholarena.co/Simulation-of-Electrical-Fields-in-Cardiac-Resynchronization-Therapy-and-Temperature-Spread-in-HF-Ablation.pdf