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Analysing-software for impedance and electrocardiography – what is currently possible?

  • Introduction: Cardiac resynchronization therapy (CRT) with biventricular (BV) pacing is an established therapy for heart failure (HF) patients with ventricular desynchronisation and reduced left ventricular (LV) function. The aim of this study was to evaluate preejection period (PEP) and left ventricular ejection time (LVET) with transthoracic signal averaging impedance and electrocardiography inIntroduction: Cardiac resynchronization therapy (CRT) with biventricular (BV) pacing is an established therapy for heart failure (HF) patients with ventricular desynchronisation and reduced left ventricular (LV) function. The aim of this study was to evaluate preejection period (PEP) and left ventricular ejection time (LVET) with transthoracic signal averaging impedance and electrocardiography in HF patients with and without BV pacing. Methods: 10 HF patients (age 68.9 ± 8 years; 2 females, 9 males) with New York Heart Association (NYHA) class 2,9 ± 0.5, 30.9 ± 10.5 % LV ejection fraction and 159.4 ± 22.9 ms QRS duration were analysed with transthoracic impedance and electrocardiography (Cardioscreen Medis, Ilmenau, Germany) and novel National Intruments LabView 2009 signal averaging software. One day after BV pacing device implantation, AV and VV delays were optimized by transthoracic impedance cardiography and stroke volume (SV) and cardiac output (CO) were gained by Cardioscreen. Results: Transthoracic impedance and electrocardiography AV and VV delay opimization was possible in all HF patients with BV pacing devices (n= 10). PEP was 154 ± 24ms without BV pacing and measured between onset of QRS in the surface electrocardiogram and onset of ventricular deflection in the impedance cardiogram. LVET was 342 ± 65ms without BV pacing and measured between onset and offset of ventricular deflection in the impedance cardiogram. The use of optimal AV and VV delay BV pacing resulted in improvement of SV from 64.1 ± 26.5 ml to 94.1 ± 33.96 ml (P < 0.05) and CO from 4.05 ± 1.36 l/min to 6.44 ± 1.56 l/min (P < 0.05). Conclusion: PEP and LVET may be useful parameters of ventricular Desynchronisation. AV and VV delay optimized BV pacing improve SV and CO. Impedance and electrocardiography with LabView 2009 signal averaging may be a simple and useful technique to optimize CRT.show moreshow less

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Metadaten
Author:Anna Haltenberger, Daniela Eisenträger, Bruno IsmerGND, Olaf Solbrig, Jürgen Querengässer, Andreas Winkler, Jakob Allmann, Anja Töpfer, Hans Reiner Figulla, Matthias HeinkeGND
Publisher:Walter de Gruyter
Place of publication:Berlin, Boston
Date of Publication (online):2011/09/30
Edition:56
Pagenumber:1
Language:English
Parent Title (Multiple languages):Biomedical Engineering / Biomedizinische Technik
Issue:S1
ISSN:0013-5585 (Print)
ISSN:1862-278X (Online)
First Page:8
Document Type:Conference Proceeding
Institutes:Hochschule Offenburg / Bibliografie
Release Date:2014/10/27
Licence (German):License LogoEs gilt das UrhG
Note:
Proceedings BMT 2011, 45. DGBMT Jahrestagung, Freiburg, 27.-30. September 2011
DOI:https://doi.org/10.1515/bmt.2011.856