The search result changed since you submitted your search request. Documents might be displayed in a different sort order.
  • search hit 13 of 58
Back to Result List

Development of a parallelizable QCM-D array for the mass spectrometric analysis of proteins

  • Quarz crystal microbalances allow the monitoring of the adsorption process of mass from a liquid to their surface. The adsorbed mass can be analysed regarding to its protein content using mass spectromety. To ensure the protein identification the results of several measurements can be combined. A high content QCM-D array was developed to allow up to ten measurements parallel. The samples can beQuarz crystal microbalances allow the monitoring of the adsorption process of mass from a liquid to their surface. The adsorbed mass can be analysed regarding to its protein content using mass spectromety. To ensure the protein identification the results of several measurements can be combined. A high content QCM-D array was developed to allow up to ten measurements parallel. The samples can be routed inside the array distributing one sample to several chips. The fluidic parts were prototyped using 3D printing. The assembled array was tight and the sample routing function could be demonstrated. A temperature controller was developed and implemented. The parameters for the PID controller were determined and the controller was shown to be able to keep the temperature constant over long time with high accuracy.show moreshow less
Metadaten
Author:Siegfried Hohmann
Place of publication:Offenburg
Year of Publication:2015
Date of first Publication:2015/06/17
Pagenumber:92
Language:English
GND Keyword:3D-Druck; Massenspektrometrie; Proteine; Temperaturregelung
Tag:3D printing; High content measurement; Mass spectrometry; QCM-D Array; Temperature control
DDC classes:600 Technik, Medizin, angewandte Wissenschaften / 620 Ingenieurwissenschaften und Maschinenbau
Advisor:Bernd Spangenberg, Gerald Brenner-Weiß
Publishing Institution:Hochschule Offenburg
Granting Institution:Hochschule Offenburg, Fakultät Maschinenbau und Verfahrenstechnik (M+V)
Date of final exam:2015/04/30
Document Type:Master's Thesis
Acces Right:Frei zugänglich
SWB-ID:165789990X
Release Date:2015/06/17
Licence (German):License LogoVeröffentlichungsvertrag für Publikationen mit Print on Demand
URN:urn:nbn:de:bsz:ofb1-opus4-9751