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Electrical Right and Left Cardiac Atrioventricular and Left Atrial Delay in Cardiac Resynchronization Therapy Responder and Non-responder with Sinus Rhythm

  • Cardiac resynchronization therapy (CRT) with hemodynamic optimized biventricular pacing is an established therapy for heart failure patients with sinus rhythm, reduced left ventricular ejection fraction and wide QRS complex. The aim of the study was to evaluate electrical right and left cardiac atrioventricular delay and left atrial delay in CRT responder and non-responder withCardiac resynchronization therapy (CRT) with hemodynamic optimized biventricular pacing is an established therapy for heart failure patients with sinus rhythm, reduced left ventricular ejection fraction and wide QRS complex. The aim of the study was to evaluate electrical right and left cardiac atrioventricular delay and left atrial delay in CRT responder and non-responder with sinus rhythm. Methods: Heart failure patients with New York Heart Association class 3.0 ± 0.3, sinus rhythm and 27.7 ± 6.1% left ventricular ejection fraction were measured by surface ECG and transesophageal bipolar left atrial and left ventricular ECG before implantation of CRT devices. Electrical right cardiac atrioventricular delay was measured between onset of P wave and onset of QRS complex in the surface ECG, left cardiac atrioventricular delay between onset of left atrial signal and onset of left ventricular signal in the transesophageal ECG and left atrial delay between onset and offset of left atrial signal in the transesophageal ECG. Results: Electrical atrioventricular and left atrial delay were 196.9 ± 38.7 ms right and 194.5 ± 44.9 ms left cardiac atrioventricular delay, and 47.7 ± 13.9 ms left atrial delay. There were positive correlation between right and left cardiac atrioventricular delay (r = 0.803 P < 0.001) and negative correlation between left atrial delay and left ventricular ejection fraction (r = −0.694 P = 0.026) with 67% CRT responder. Conclusions: Transesophageal electrical left cardiac atrioventricular delay and left atrial delay may be useful preoperative atrial desynchronization parameters to improve CRT optimization.show moreshow less

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Metadaten
Author:Gudrun Dannberg, Tobias Heinke, Helmut Kühnert, Matthias Heinke
Editor:Lenka Lhotska
Creating Corporation:The International Federation for Medical and Biological Engineering, IFMBE
Publisher:Springer
Place of publication:Singapore
Year of Publication:2018
Pagenumber:4
ISBN:978-981-10-9038-7
Language:English
Tag:Cardiac resynchronization therapy, Biventricular pacing, Left atrial ECG, Transesophageal electrocardiography, Left atrial delay, Atrioventricular delay,Left cardiac ECG
Parent Title (English):World Congress on Medical Physics and Biomedical Engineering 2018, IFMBE Proceedings
ISSN:1433-9277
First Page:139
Last Page:142
Document Type:Conference Proceeding
Institutes:Hochschule Offenburg / Bibliografie
Release Date:2019/01/07
Licence (German):License LogoEs gilt das UrhG
DOI:https://doi.org/10.1007/978-981-10-9038-7_25