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Biodegradation and biocompatibility of molybdenum as an implant material

  • Biodegradable metals have entered the implant market in recent years, but still do not show fully satisfactory degradation behaviour and mechanical properties. In contrast, it has been shown that pure molybdenum has an excellent combination of the required properties in this respect. We report on PM based screen printing of thin-walled molybdenum tubes as a processing step for medical stentBiodegradable metals have entered the implant market in recent years, but still do not show fully satisfactory degradation behaviour and mechanical properties. In contrast, it has been shown that pure molybdenum has an excellent combination of the required properties in this respect. We report on PM based screen printing of thin-walled molybdenum tubes as a processing step for medical stent manufacture. We also present data on the in vivo degradation and biocompatibility of molybdenum. The degradation of molybdenum wires implanted in the aorta of rats was evaluated by SEM and EDX. Biocompatibility was assessed by histological investigation of organs and analysis of molybdenum levels in tissue extracts and body fluids. Degradation rates of up to 13.5 μm/y were observed after 12 months. No histological changes or elevated molybdenum levels in organ tissues were observed. In summary, the results further underline that molybdenum is a highly promising biodegradable metallic material.show moreshow less

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Metadaten
Document Type:Conference Proceeding
Conference Type:Konferenzartikel
Zitierlink: https://opus.hs-offenburg.de/6648
Bibliografische Angaben
Title (English):Biodegradation and biocompatibility of molybdenum as an implant material
Conference:WorldPM 2022 Congress & Exhibition. Developing the powder metallurgy future, 9.-13. Oktober 2022, Lyon, France
Author:Georg Pöhle, Antje Schauer, Christian Redlich, Peggy Barthel, Anita Maennel, Volker Adams, Thomas Studnitzky, Thomas Weißgärber, Axel Linke, Peter QuadbeckStaff MemberORCiDGND
Year of Publication:2022
Place of publication:Chantilly, France
Publisher:European Powder Metallurgy Association EPMA
Page Number:8
Parent Title (English):WorldPM 2022 Congress & Exhibition : Proceedings
Volume:2022
ISBN:978-1-899072-55-2
URL:https://www.epma.com/publications/euro-pm-proceedings/world-pm2022-proceedings
Language:English
Inhaltliche Informationen
Institutes:Fakultät Elektrotechnik, Medizintechnik und Informatik (EMI) (ab 04/2019)
Institutes:Bibliografie
DDC classes:600 Technik, Medizin, angewandte Wissenschaften
GND Keyword:Medizintechnik
Tag:biocompatibility test; biodegradable; biomaterials; molybdenum
Funded by (textarea):Sächsisches Ministerium für Wissenschaft, Kultur und Tourismus SMWK mit der Sächsischen Aufbaubank SAB, finanziert mit European Financial Resources (EFRE)
Formale Angaben
Relevance:Konferenzbeitrag: h5-Index < 30
Open Access: Closed 
Licence (German):License LogoUrheberrechtlich geschützt