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Semi-invasive determination of interventricular and intraleftventricular conduction delay in CRT patients

  • Using guideline parameters for indication of cardiac resynchronization therapy (CRT), only about two thirds of the patients improve clinically. Unfortunately both, surface ECG and echo are uncertain to predict CRT response. To better characterize cardiac desynchronization in heart failure, interventricular (IVCD) and intra-leftventricular conduction delays (ILVCD) were measured by esophageal leftUsing guideline parameters for indication of cardiac resynchronization therapy (CRT), only about two thirds of the patients improve clinically. Unfortunately both, surface ECG and echo are uncertain to predict CRT response. To better characterize cardiac desynchronization in heart failure, interventricular (IVCD) and intra-leftventricular conduction delays (ILVCD) were measured by esophageal left ventricular electrogram (LVE). Recordings in 43 CRT patients (34m, 9f, age: 64.7 ± 9.5yrs) evidenced only weak correlation between IVCD and QRS of 0.53 and between ILVCD and QRS of 0.33. This demonstrated that QRS duration is not a reliable indicator of desynchronization. Therefore, the study resulted into development of LVE feature for a programmer with implant support device. It can be used interoperatively to guide the left ventricular electrode location in order to increase responder rate in CRT.show moreshow less

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Author:Bruno IsmerGND, Kirsten-Maria Rotter, Matthias HeinkeGND, Ibrahim Akin, Katharina Kroll, Stephanie Schell-Dieckel, Ulrich Trautwein, Wolfgang Voß, Christoph Melzer, Frank Weber, Ralf Peters, Christoph A. Nienaber
Publisher:Walter de Gruyter
Place of publication:Berlin, Boston
Date of Publication (online):2010/10/26
Language:English
Parent Title (Multiple languages):Biomedizinische Technik = Biomedical engineering
Volume:55
Issue:S1
ISSN:0013-5585 (Print)
ISSN:1862-278X (Online)
First Page:141
Last Page:143
Document Type:Conference Proceeding
Institutes:Hochschule Offenburg / Bibliografie
Release Date:2015/02/16
Licence (German):License LogoEs gilt das UrhG
Note:
Proceedings BMT 2010, 44. DGBMT Jahrestagung, Freiburg, 3-Länder-Tagung D-A-CH, Rostock, 6.-9.10.2010
DOI:https://doi.org/10.1515/bmt.2010.709