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Cryoballoon model and simulation of catheter ablation for pulmonary vein isolation in atrial fibrillation

  • Pulmonary vein isolation (PVI) is a common therapy in atrial fibrillation (AF). The cryoballoon was invented to isolate the pulmonary vein in one step and in a shorter time than a point-by-point radiofrequency (RF) ablation. The aim of the study was to model two cryoballoon catheters, one RF catheter and to integrate them into a heart rhythm model for the static and dynamic simulation of PVIPulmonary vein isolation (PVI) is a common therapy in atrial fibrillation (AF). The cryoballoon was invented to isolate the pulmonary vein in one step and in a shorter time than a point-by-point radiofrequency (RF) ablation. The aim of the study was to model two cryoballoon catheters, one RF catheter and to integrate them into a heart rhythm model for the static and dynamic simulation of PVI by cryoablation and RF ablation in AF. The modeling and simulation were carried out using the electromagnetic and thermal simulation software CST (CST, Darmstadt). Two cryoballons and one RF ablation catheter were modeled based on the technical manuals of the manufacturers Medtronic and Osypka. The PVI especially the isolation of the left inferior pulmonary vein using a cryoballoon catheter was performed with a -50 °C heatsource and an exponential signal. The temperature at the balloon surface was -50 °C after 20 s ablation time, -24 °C from the balloon 0,5 mm in the myocardium, at a distance of 1 mm -3 °C, at 2 mm 18 °C and at a distance of 3mm 29 °C. PVI with RF energy was simulated with an applied power of 5 W at 420 kHz at the distal 8 mm ablation electrode. The temperature at the tip electrode was 110 °C after 15 s ablation time, 75 °C from the balloon at 0,5 mm in the myocardium, at a distance of 1 mm 58 °C, at 2 mm 45 °C and at a distance of 3 mm 38 °C. Virtual heart rhythm and catheter models as well as the simulation of the temperature allow the simulation of PVI in AF by cryo ablation and RF ablation. The 3D simulation of the temperature profile may be used to optimize RF and cryo ablation.show moreshow less

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Metadaten
Author:Robin Müssig, Matthias Heinke, Johannes Hörth
Publisher:De Gruyter
Place of publication:Berlin
Year of Publication:2018
Language:English
Tag:atrial fibrillation; cryo ablation; cryoballoon; pulmonary vein isolation; radiofrequency ablation
DDC classes:600 Technik, Medizin, angewandte Wissenschaften
Parent Title (English):Current Directions in Biomedical Engineering
Volume:4
Issue:1
ISSN:2364-5504
First Page:473
Last Page:475
Document Type:Article (reviewed)
Institutes:Hochschule Offenburg / Bibliografie
Acces Right:Frei zugänglich
Release Date:2018/12/05
Licence (German):License LogoEs gilt das UrhG
URL:https://www.degruyter.com/view/j/cdbme.2018.4.issue-1/cdbme-2018-0113/cdbme-2018-0113.xml?format=INT
DOI:https://doi.org/10.1515/cdbme-2018-0113