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A Validated Quantification of Methadone in Liquids Using Thin-Layer Chromatography and a Flatbed Scanner

  • We present a videodensitometric quantification method for methadone in syrup, separated by thin-layer chromatography (TLC). The quantification is based on a derivation reaction with Dragendorf reagent. Measurements were carried out using a 16-bit flatbed scanner. The range of linearity covers two magnitudes of power using the Kubelka-Munk expression for data transformation. The separation methodWe present a videodensitometric quantification method for methadone in syrup, separated by thin-layer chromatography (TLC). The quantification is based on a derivation reaction with Dragendorf reagent. Measurements were carried out using a 16-bit flatbed scanner. The range of linearity covers two magnitudes of power using the Kubelka-Munk expression for data transformation. The separation method is inexpensive, fast, and reliable.show moreshow less

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Metadaten
Document Type:Article (unreviewed)
Zitierlink: https://opus.hs-offenburg.de/2162
Bibliografische Angaben
Title (English):A Validated Quantification of Methadone in Liquids Using Thin-Layer Chromatography and a Flatbed Scanner
Author:Bernd SpangenbergStaff MemberORCiDGND, Marion Weyandt-Spangenberg
Year of Publication:2016
First Page:59
Last Page:65
Parent Title (English):JPC : Journal of Planar Chromatography - Modern TLC
Volume:29
Issue:1
ISSN:1789-0993 (Online)
ISSN:0933-4173 (Print)
DOI:https://doi.org/10.1556/1006.2016.29.1.7
Language:English
Inhaltliche Informationen
Institutes:Fakultät Maschinenbau und Verfahrenstechnik (M+V)
Institutes:Bibliografie
GND Keyword:Dünnschichtchromatographie; Flüssigkeit; Methadon
Formale Angaben
Open Access: Closed Access 
Licence (German):License LogoUrheberrechtlich geschützt