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Das Institut für Angewandte Forschung (IAF) der Hochschule Offenburg arbeitet seit mehreren Jahren an der Entwicklung der elektronischen Pille, mit der Medikamente im Darm telemetrisch gesteuert auf Kommando freigesetzt werden können. Das System benötigt dazu eine hochminiaturisierte Elektronik, die in Form eines integrierten Schaltkreises (ASIC) entwickelt wurde.
Das Institut für Angewandte Forschung (IAF) der Hochschule Offenburg ist seit mehr als 3 Jahren an der Entwicklung einer elektronischen Pille engagiert, die die bisher übliche chemische Freisetzung von Medikamenten im Darm durch eine gesteuerte, über Telemetrie ausgelöste Freisetzung ersetzen soll Damit lassen sich Therapien durchführen und Medikamente verwenden, die in der klassischen Form nicht möglich sind.
A new, small, and optimized for low power processor core named SIRIUS has been developed, simulated, synthesized to a netlist and verified. From this netlist, containing only primitives like gates and flip-flops, a mapping to an ASIC - or FPGA technology can easily be done with existing synthesizer tools, allowing very complex SOC designs with several blocks. Emulation via FPGA can be done on already simple setups and cheap hardware because of the small core size. The performance is estimated 50 MIPS on Cyclone II FPGA and about 100 MIPS on a 0.35 CMOS 5M2P technology with 4197 primitives used for the core, including a 16 x 16 multiplier. An example design of the ASIC for an electronic ePille device currently in development is shown.
A platform of an electronic capsule is being developed for multi-task medical assistant application. It includes a near field telemetry unit for bidirectional communication system of 115 KHz low carrier frequency for inductive data transmission suited for human body energy transfer. The system triggers an actuator for drug delivery in various time and release forms via wireless external control, it has the ability to record temperature, measure pH of the body (additional sensors), and retrieve data to the outside. It consists of a 32bit processor, memory, external peripheries, and detection facility. The complete system is designed to fit small-size mass medical application with low power consumption, size of 7x25mm. The system is designed, simulated and emulated on FPGA. A final layout of the complete chip design is still under progress.
The application relates to an electronic pill for dispensing a substance, in particular a drug, in a human or animal body in a controllable manner, said electronic pill having a housing (3) in which the substance (17) to be dispensed is accommodated and in which a dispensing opening (47) for dispensing the substance (17) is provided, wherein the substance (17) can be subjected to a predetermined pressure in order to be dispensed from the housing (3), having an electronic control unit (53, 59, 61, 63), and having a valve unit (33) which is arranged in the course of a dispensing path and can be moved from an open position to a closed position by the control unit (53, 59, 61, 63). In the housing (3), a throttle section (45) is provided in the course of the dispensing path for the substance (17) to be dispensed.