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Special implant connection module was developed to combine full features of two commercial heart rhythm simulators, ARSI-4 and Intersim II, into a master-slave teaching system. Seven workstations were equipped with the Carelink and Homemonitoring remote patient monitoring systems. This combination enables in-vitro training of physicians, nurses and students in pace-maker and defibrillator measurements during implantation and individual programming in the follow-up. Thus, extended sets of arrhythmias and electrode problems can be used to simulate problems and their solutions in a wide range of the clinical routine.
In the brain-cell microenvironment, diffusion plays an important role: apart from delivering glucose and oxygen from the vascular system to brain cells, it also moves informational substances between cells. The brain is an extremely complex structure of interwoven, intercommunicating cells, but recent theoretical and experimental works showed that the classical laws of diffusion, cast in the framework of porous media theory, can deliver an accurate quantitative description of the way molecules are transported through this tissue. The mathematical modeling and the numerical simulations are successfully applied in the investigation of diffusion processes in tissues, replacing the costly laboratory investigations. Nevertheless, modeling must rely on highly accurate information regarding the main parameters (tortuosity, volume fraction) which characterize the tissue, obtained by structural and functional imaging. The usual techniques to measure the diffusion mechanism in brain tissue are the radiotracer method, the real time iontophoretic method and integrative optical imaging using fluorescence microscopy. A promising technique for obtaining the values for characteristic parameters of the transport equation is the direct optical investigation using optical fibers. The analysis of these parameters also reveals how the local geometry of the brain changes with time or under pathological conditions. This paper presents a set of computations concerning the mass transport inside the brain tissue, for different types of cells. By measuring the time evolution of the concentration profile of an injected substance and using suitable fitting procedures, the main parameters characterizing the tissue can be determined. This type of analysis could be an important tool in understanding the functional mechanisms of effective drug delivery in complex structures such as the brain tissue. It also offers possibilities to realize optical imaging methods for in vitro and in vivo measurements using optical fibers. The model also may help in radiotracer biomarker models for the understanding of the mechanism of action of new chemical entities.
Various Rapid Prototyping methods have been available for the production of physical architectural models for a few years. This paper highlights in particular the advantages of 3D printing for the production of detailed architectural models. In addition, the current challenges for the creation and transfer of data are explained. Furthermore, new methods are being developed in order to improve both the technical and economic boundary conditions for the application of 3DP. This makes the production of models with very detailed interior rooms possible. The internal details are made visible by dividing the complex overall model into individual models connected by means of an innovative plug-in system. Finally, two case studies are shown in which the developed methods are applied in order to implement detailed architectural models. Additional information about manufacturing time and costs of the architectural models in the two case studies is given.
Für langfaserverstärkte Thermoplaste (LFT) wird ein repräsentatives Volumenelement (RVE) für FEM-Simulationen generiert. Dies geschieht unter Berücksichtigung von mikrostrukturellen Kenngrößen wie Faserorientierungsverteilung, -volumengehalt und -längenverteilung, die für einen charakteristischen Werkstoffzustand experimentell ermittelt wurden. Mittels Mikrostruktursimulationen wird das Kriechverhalten von LFT untersucht. Das viskoelastische Verhalten der Matrix wird experimentell an Substanzproben aus Polypropylen ermittelt und in die RVE-Simulationen mit einem modifizierten Burgers-Modell implementiert. Schließlich werden die Rechnungen mit verschiedenen, fiktiven sowie experimentell ermittelten Faserlängenverteilungen mit Kriechversuchen am LFT verglichen. Es zeigt sich eine starke Abhängigkeit des Kriechverhaltens von der Faserlänge und eine hohe Prognosegüte der Simulationen, die die experimentell ermittelte Längenverteilung berücksichtigen.
Die Lehre auf dem Gebiet der rechnerunterstützten Methoden in der Produktentwicklung verkörpert einen zentralen Schwerpunkt der Ingenieursausbildung. Dies bedingt eine kontinuierliche Weiterentwicklung der Inhalte und der didaktischen Unterrichtsmethoden. In diesem Artikel wird die Entwicklung eines didaktischen Konzepts für die Konstruktionsausbildung zur Verbesserung der Präsentationskompetenz und Teamfähigkeit der Studierenden beschrieben und über erste Erfahrungen aus der Umsetzung in die Lehrveranstaltung „CAD/CAE“ berichtet. Die Studierenden erarbeiten in nach der Rundlitzenseilmethode strukturierten Gruppen numerische Lösungen zu Variantenrechnungen einer FEM-Aufgabe, nämlich „Berechnung der Formzahlen an Profilwellen mit Entlastungskerben“. Sie stellen ihre Ergebnisse in Form von 100-Sekunden-Vorträgen dar. Die Bewertung dieser Leistungen erfolgt nach dem Ampelschema. Eine detaillierte statistisch-psychologische Evaluation dieses didaktischen Konzepts ist Ziel weiterführender Untersuchungen.
In this paper the fatigue life of three cast iron materials, namely EN-GJS-700, EN-GJV-450 and EN-GJL-250, is predicted for combined thermomechanical fatigue and high cycle fatigue loading. To this end, a mechanism-based model is used, which is based on microcrack growth. The model considers crack growth due to low frequency loading (thermomechanical and low cycle fatigue) and due to high cycle fatigue. To determine the model parameters for the cast iron materials, fatigue tests are performed under combined loading and crack growth is measured at room temperature using the replica technique. Superimposed high cycle fatigue leads to an accelerated crack growth as soon as a critical crack length and thus the threshold stress intensity factor is exceeded. The model takes this effect into account and predicts the fatigue lives of all cast iron materials investigated under combined loadings very well.
Not only is the number of new devices constantly increasing, but so is their application complexity and power. Most of their applications are in optics, photonics, acoustic and mobile devices. Working speed and functionality is achieved in most of media devices by strategic use of digital signal processors and microcontrollers of the new generation. Considering all these premises of media development dynamics, the authors present how to integrate microcontrollers and digital signal processors in the curricula of media technology lectures by using adequate content. This also includes interdisciplinary content that consists of using the acquired knowledge in media software. These entries offer a deeper understanding of photonics, acoustics and media engineering.
The communication technologies for automatic meter reading (smart metering) and for energy production and distribution networks (smart grid) have the potential to be one of the first really highly scaled machine-to-machine-M2M-applications. During the last years, two very promising developments around the wireless part of the smart grid communication were initialized, which possibly could have an impact on the network architectures and the markets far beyond Germany and far beyond energy automation. Besides the specification of the OMS Group of a security extension to the Wireless M-Bus protocol (EN13757-4), the German Federal Office for Information Security (Bundesamt für Sicherheit in der Informationstechnik, BSI) has designed a Protection Profile (PP) and a Technical Directive (TR) for the communication unit of an intelligent measurement system (Smart Meter Gateway), which were released in March 2013. This design uses state of the art technologies and prescribes their implementation in real-life systems. At first, the proposed paper will present the most important characteristics of this architecture. It will then give an insight into the implementation of the OMS security protocols, which imply the usage of a mutually authenticated SSL protocol also in the Local Metrological Network. This is achieved with the help of an additional Authentication and Fragmentation Layer (AFL). This secure communication will be terminated in a BSI conformant secure smart meter gateway, which is developed in a different project and described in the second step. Finally, the contribution will discuss the integration of such a metering network into an overall telecommunication network and PKI infrastructure.
Durch eine stetige Preissteigerung der fossilen Energieträger werden auch im Bereich der mobilen Arbeitsmaschinen neben einer hohen Zuverlässig u.a. Forderungen nach steigenden Gesamtwirkungsgraden, mit der hierdurch einhergehenden Energieeffizienz, forciert. Auch bei mobilen Arbeitsmaschinen ist der häufig eingeschränkt zur Verfügung stehende Bauraum für Traktionsantriebe eine Herausforderung. Ziel dieser Veröffentlichung ist ein allgemeingültiger Vergleich verschiedener elektrischer Antriebsarten als Traktionsantrieb für mobile Arbeitsmaschinen.
Android is an operating system which was developed for use in smart mobile phones and is the current leader in this market. A lot of efforts are being spent to make Android available to the embedded world, as well. Many embedded systems do not have a local GUI and are therefore called headless devices. This paper presents the results of an analysis of the general suitability of Anroid in headless embedded systems and ponders the advantages and disadvantages. It focuses on the hardware related issues, i.e. to what extent Android supports hardware peripherals normally used in embedded systems.
Decrease of non-responder rate is the main chal-lenge in cardiac resynchronization therapy. The problem could be solved, partly, in the follow-up by consequent indi-vidualization of hemodynamic pacing parameters. The eso-phageal electrogram feature of the Biotronik ICS 3000 programmer was used in the follow-up of 20 heart failure patients carrying implants for cardiac resynchronization therapy. Adverse hemodynamic programming of the sensed and paced AV delay could be easily observed and replaced by the individual optimal duration in 3 patients (15%) VDD and DDD operation.This result proves the value of esophageal electrogram recording CRT follow-up.