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Zeitliche Anpassung führt zu verbesserter Schalllokalisation bei bimodal versorgten CI-/HG-Trägern
(2021)
Bei bimodal versorgten Cochlea-Implantaten (CI) / Hörgerät (HG)-Trägern entsteht durch die unterschiedliche Signalverarbeitung der Geräte eine konstante interaurale Zeitverzögerung in der Größenordnung von mehreren Millisekunden. Für MED-EL CI-Systeme in Kombination mit verschiedenen HG-Typen haben wir den jeweiligen Device-Delay-Mismatch quantifiziert. In der aktuellen Studie untersuchen wir den Einfluss der Device-Delay-Mismatch bei simulierten und tatsächlichen bimodalen Hörern auf die Genauigkeit der Schalllokalisation.
Um den Device-Delay-Mismatch bei bimodal versorgten Patienten zu verringern, haben wir die CI-Stimulation um die gemessene HG-Signallaufzeit und zwei weitere Werte verzögert. Nach einer Angewöhnungsphase war der effektive Winkelfehler bei Verzögerung um die HG-Signallaufzeit hochsignifikant reduziert im Vergleich zu der Testkondition ohne CI-Verzögerung (mittlere Verbesserung: 11 % ; p < .01, Wilcoxon Signed Rank Test). Aber auch mit den beiden weiteren Verzögerungswerten wurden Verbesserungen erreicht. Anhand der Ergebnisse lässt sich der optimale patientenspezifische Verzögerungswert näher eingrenzen.
Generative convolutional deep neural networks, e.g. popular GAN architectures, are relying on convolution based up-sampling methods to produce non-scalar outputs like images or video sequences. In this paper, we show that common up-sampling methods, i.e. known as up-convolution or transposed convolution, are causing the inability of such models to reproduce spectral distributions of natural training data correctly. This effect is independent of the underlying architecture and we show that it can be used to easily detect generated data like deepfakes with up to 100% accuracy on public benchmarks. To overcome this drawback of current generative models, we propose to add a novel spectral regularization term to the training optimization objective. We show that this approach not only allows to train spectral consistent GANs that are avoiding high frequency errors. Also, we show that a correct approximation of the frequency spectrum has positive effects on the training stability and output quality of generative networks.
Background: Transesophageal left atrial (LA) pacing and transesophageal LA ECG recording are semi-invasive techniques for diagnostic and therapy of supraventricular rhythm disturbance. Cardiac resynchronization therapy (CRT) with right atrial (RA) sensed biventricular pacing is an established therapy for heart failure patients with reduced left ventricular (LV) ejection fraction, sinus rhythm and interventricular electrical desynchronization.
Purpose: The aim of the study was to evaluate electromagnetic and voltage pacing fields of the combination of RA pacing, LA pacing and biventricular pacing in patients with long interatrial and interventricular electrical desynchronization.
Methods: The modelling and electromagnetic simulations of transesophageal LA pacing in combination with RA pacing and biventricular pacing would be staged and analyzed with the CST (Computer Simulation Technology) software. Different electrodes were modelled in order to simulate different types of bipolar pacing in the 3D-CAD Offenburg heart rhythm model: The bipolar Solid S (Biotronik) electrode where modelled for RA pacing and right ventricular (RV) pacing, Attain 4194 (Medtronic) for LV pacing and TO8 (Osypka) multipolar esophageal electrode with hemispheric electrodes for LA pacing.
Results: The pacemaker amplitudes for the electromagnetic pacing simulations were performed with 3 V for RA pacing, 1.5 V for RV pacing, 50 V for LA pacing and 3V for LV pacing with pacing impulse duration of 0.5 ms for RA, RV and LV pacing and 10 ms for LA pacing. The atrioventricular pacing delay after RA pacing was 140 ms. The different pacing modes AAI, VVI, DDD, DDD0V and DDD0D were evaluated for the analysis of the electric pacing field propagation of pacemaker, CRT and LA pacing. The pacing results were compared at minimum (LOW) and maximum (HIGH) parameter settings. While the LOW setting produced fewer tetrahedral and more inaccurate results, the HIGH setting produced many tetrahedral and therefore more accurate results.
Conclusions: The simulation of the combination of transesophageal LA pacing with RA sensed biventricular pacing is possible with the Offenburg heart rhythm model. The new temporary 4-chamber pacing method may be additional useful method in CRT non-responders with long interatrial electrical delay.
Mit der Implementierung sowie einer anschließenden aussagekräftigen Evaluierung, soll das, visuelle-inertiale Kartierungs- und Lokalisierungssystem maplab analysiert werden. Hierbei basiert die Kartierung bzw. Lokalisierung auf der Detektion von Umgebungsmerkmalen. Neben der Möglichkeit der Kartenerstellung besteht ferner die Option, mehrere Karten zu fusionieren und somit weitreichende Gebiete zu kartieren sowie für weitere Datenauswertungen zu nutzen. Aufgrund der Durchführung und Bewertung der Ergebnisse in unterschiedlichen Anwendungsszenarien zeigt sich, dass maplab besonders zur Kartierung von Räumen bzw. kleinen Gebäudekomplexen geeignet ist. Die Möglichkeit der Kartenfusionierung bietet weiterhin die Option, den Informationsgehalt von Karten zu erhöhen, welches die Effektivität für eine anschließende Lokalisierung steigert. Bei wachsender Kartierungsgröße hingegen zeigt sich jedoch eine Vergrößerung geometrischer Inkonsistenzen.
Die Positionierung mobiler Systeme mit hoher Genauigkeit ist eine Voraussetzung für intelligentes autonomes Verhalten, sowohl in der Feldrobotik als auch in industriellen Umgebungen. Dieser Beitrag beschreibt den Aufbau einer Roboterplattform und ihre Verwendung für den Test und die Bewertung von Kalman-Filter-Konfigurationen. Der Aufbau wurde mit einem mobilen Roboter Husky A200 und einem LiDAR-Sensor (Light Detection and Ranging) realisiert. Zur Verifizierung des vorgeschlagenen Aufbaus wurden fünf verschiedene Szenarien ausgearbeitet. Mit denen wurden die Filter auf ihre Leistungsfähigkeit hinsichtlich der Genauigkeit der Positionsbestimmung getestet.
A method for evaluating skin cancer detection based on millimeter-wave technologies is presented. For this purpose, the relative permittivities are calculated using the effective medium theory for the benign and cancerous lesion, considering the change in water content between them. These calculated relative permittivities are further used for the simulation and evaluation of skin cancer detection using a substrate-integrated waveguide probe. A difference in the simulated scattering parameters S 11 of up to 13dB between healthy and cancerous skin can be determined in the best-case.
Convolutional neural networks (CNN) define the state-of-the-art solution on many perceptual tasks. However, current CNN approaches largely remain vulnerable against adversarial perturbations of the input that have been crafted specifically to fool the system while being quasi-imperceptible to the human eye. In recent years, various approaches have been proposed to defend CNNs against such attacks, for example by model hardening or by adding explicit defence mechanisms. Thereby, a small “detector” is included in the network and trained on the binary classification task of distinguishing genuine data from data containing adversarial perturbations. In this work, we propose a simple and light-weight detector, which leverages recent findings on the relation between networks’ local intrinsic dimensionality (LID) and adversarial attacks. Based on a re-interpretation of the LID measure and several simple adaptations, we surpass the state-of-the-art on adversarial detection by a significant m argin and reach almost perfect results in terms of F1-score for several networks and datasets. Sources available at: https://github.com/adverML/multiLID
In this study, an approach to a microwave-based radar system for the localization of objects has been proposed. This could be particularly useful in microwave imaging applications such as cardiac catheter detection. An experimental system is defined and realized with the selection of an appropriate antenna design. Hardware control functions and different imaging algorithms are implemented as well. The functionality of this measurement setup has been analyzed considering multiple testscenarios and it is proved to be capable of locating multiple objects as well as expanded objects.
As industrial networks continue to expand and connect more devices and users, they face growing security challenges such as unauthorized access and data breaches. This paper delves into the crucial role of security and trust in industrial networks and how trust management systems (TMS) can mitigate malicious access to these networks.The TMS presented in this paper leverages distributed ledger technology (blockchain) to evaluate the trustworthiness of blockchain nodes, including devices and users, and make access decisions accordingly. While this approach is applicable to blockchain, it can also be extended to other areas. This approach can help prevent malicious actors from penetrating industrial networks and causing harm. The paper also presents the results of a simulation to demonstrate the behavior of the TMS and provide insights into its effectiveness.