Refine
Document Type
- Conference Proceeding (25) (remove)
Conference Type
- Konferenzartikel (23)
- Konferenz-Abstract (1)
- Sonstiges (1)
Language
- English (25)
Has Fulltext
- no (25) (remove)
Is part of the Bibliography
- yes (25) (remove)
Keywords
- Education (3)
- Gamification (2)
- University students (2)
- VR (2)
- Astronomical optics (1)
- Augmented Reality (1)
- Augmented reality (1)
- Binary Executable (1)
- COVID (1)
- Circular polarizing filter (1)
Institute
- Fakultät Medien (M) (ab 22.04.2021) (25) (remove)
Open Access
- Closed (10)
- Open Access (9)
- Closed Access (6)
- Hybrid (4)
- Diamond (2)
- Bronze (1)
Objective: Dickkopf 3 (DKK3) has been identified as a urinary biomarker. Values above 4000 pg/mg creatinine (Cr) were linked with a higher risk of short-term decline of kidney function (J Am Soc Nephrol 29: 2722–2733). However, as of today, there is little experience with DKK3 as a risk marker in everyday clinical practice. We used algorithm-based data analysis to evaluate the potential dependence of DKK3 in a cohort from a large single center in Germany.
Method: DKK3 was measured in all CKD patients in our center October 1 st 2018 till Dec. 31 2019, together with calculated GFR (eGFR) and urinary albumin/creatinine ratio (UACR). Kidney transplant patients were excluded. Until the end of follow-up Dec 31 st 2021, repeated measurements were performed for all parameters. Data analysis was performed using MD-Explorer (BioArtProducts, Rostock, Germany) and Python with multiple libraries. Linear regression models were applied in patients for DKK3, eGFR and UACR. Comparison of the models was performed with a twosided Kolmogorov-Smirnov test.
Results: 1206 DKK3 measurements were performed in 1103 patients (621 male, age 70yrs, eGFR 29,41 ml/min/1.73qm, UACR 800 mg/g). 134 patients died during follow-up. DKK3 mean was 2905 pg/mg Cr (max. 20000, 75 % percentile 3800). 121 pts had DKK3 > 4000. At the end of follow-up 7 % of patients with DKK3 < 4000 (initial eGFR 17.6) versus 39.6 % of patients with DDK3 > 4000 (initial eGFR 15.7) underwent dialysis. Compared to eGFR and UACR at baseline, DKK3 > 4000 performed best to predict eGFR loss over the next 12 months.
Conclusion: In this cohort of CKD patients, DKK3 > 4000 at baseline predicted the eGFR slope better than eGFR or UACR at baseline. DKK3 > 4000 reflected a higher risk of progression towards ESRD in patients with similar baseline eGFR levels.
Complex tourism products with intangible service components are difficult to explain to potential customers. This research elaborates the use of virtual reality (VR) in the field of shore excursions. A theoretical research model based on the technology acceptance model was developed, and hypotheses were proposed. Cruise passengers were invited to test 360° excursion images on a landing page. Data was collected using an online questionnaire. Finally, data was analyzed using the PLS-SEM method. The results provide theoretical implications on technology acceptance model (TAM) research in the field of cruise tourism. Furthermore, the results and implications indicate the potential of virtual 360° shore excursion presentations for the cruise industry.
VR-based implementation of interactive laboratory experiments in optics and photonics education
(2022)
Within the framework of a developed blended learning concept, a lot of experience has already been gained with a mixture of theoretical lectures and hands-on activities, combined with the advantages of modern digital media. Here, visualizations using videos, animations and augmented reality have proven to be effective tools to convey learning content in a sustainable way. In the next step, ideas and concepts were developed to implement hands-on laboratory experiments in a virtual environment. The main focus is on the realization of virtual experiments and environments that give the students a deep insight into selected subfields of optics and photonics.
Redesigning a curriculum for teaching media technology is a major challenge. Up-to-date teaching and learning concepts are necessary that meet the constant technological progress and prepare students specifically for their professional life. Teaching and studying should be characterized by a student-oriented teaching and learning culture. In order to achieve this goal, consistent evaluation is essential. The aim of the evaluation concept presented here is to generate structured information regarding the quality of content-related, didactic and organizational aspects of teaching. The exchange of opinions between students and lecturers should be encouraged in order to continuously improve the teaching and learning processes.
Brand-related-user-generated-content allows companies to achieve several important objectives, such as increasing sales and creating higher user engagement. In this paper a research framework is developed that provides an overview of the necessary processes to successfully use brand-related-user-generated-content. The framework also helps managers to understand the main motives of users when posting brand-related-user-generated-content. Expert interviews were carried out to validate the research framework. The results from the interviews support the proposed framework. Brand-related-user-generated-content can increase purchase intention and the community engagement. From a user’s perspective the opportunity to interact with a brand and be featured on official brand channels could be seen as the main motivation for creating brand-related-user-generated-content.
The identification of vulnerabilities is an important element in the software development life cycle to ensure the security of software. While vulnerability identification based on the source code is a well studied field, the identification of vulnerabilities on basis of a binary executable without the corresponding source code is more challenging. Recent research [1] has shown how such detection can generally be enabled by deep learning methods, but appears to be very limited regarding the overall amount of detected vulnerabilities. We analyse to what extent we could cover the identification of a larger variety of vulnerabilities. Therefore, a supervised deep learning approach using recurrent neural networks for the application of vulnerability detection based on binary executables is used. The underlying basis is a dataset with 50,651 samples of vulnerable code in the form of a standardised LLVM Intermediate Representation. Te vectorised features of a Word2Vec model are used to train different variations of three basic architectures of recurrent neural networks (GRU, LSTM, SRNN). A binary classification was established for detecting the presence of an arbitrary vulnerability, and a multi-class model was trained for the identification of the exact vulnerability, which achieved an out-of-sample accuracy of 88% and 77%, respectively. Differences in the detection of different vulnerabilities were also observed, with non-vulnerable samples being detected with a particularly high precision of over 98%. Thus, our proposed technical approach and methodology enables an accurate detection of 23 (compared to 4 [1]) vulnerabilities.
In the field of network security, the detection of possible intrusions is an important task to prevent and analyse attacks. Machine learning has been adopted as a particular supporting technique over the last years. However, the majority of related published work uses post mortem log files and fails to address the required real-time capabilities of network data feature extraction and machine learning based analysis [1-5]. We introduce the network feature extractor library FEX, which is designed to allow real-time feature extraction of network data. This library incorporates 83 statistical features based on reassembled data flows. The introduced Cython implementation allows processing individual packets within 4.58 microseconds. Based on the features extracted by FEX, existing intrusion detection machine learning models were examined with respect to their real-time capabilities. An identified Decision-Tree Classifier model was thus further optimised by transpiling it into C Code. This reduced the prediction time of a single sample to 3.96 microseconds on average. Based on the feature extractor and the improved machine learning model an IDS system was implemented which supports a data throughput between 63.7 Mbit/s and 2.5 Gbit/s making it a suitable candidate for a real-time, machine-learning based IDS.
We consider large scale Peer-to-Peer Sensor Networks, which try to calculate and distribute the mean value of all sensor inputs. For this we design, simulate and evaluate distributed approximation algorithms which reduce the number of messages. The main difference of these algorithms is the underlying communication protocol which all use the random call model, where in discrete round model each node can call a random sensor node with uniform probability.The amount of data exchanged between sensor nodes and used in the calculation process affects the accuracy of the aggregation results leading to a trade-off situation. The key idea of our algorithms is to limit the sample size using the Finite Population Correction (FPC) method and collect the data using a distribution aggregation using Push-Pull Sampling, Pull Sampling, and Push Sampling communication protocols. It turns out that all methods show exponential improvement of Mean Squared Error (MSE) with the number of messages and rounds.
Public educational institutions are increasingly confronted with a decline in the number of applicants, which is why competition between colleges and universities is also intensifying. For this reason, it is important to position oneself as an institution in order to be perceived by the various target groups and to differentiate oneself from the competition. In this context, the brand and thus its perception and impact play a decisive role, especially in view of the desired communication of the institution's own values and its self-image, the brand identity. To this end, emotions serve as an approach to creating positive stimulation and brand loyalty.