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Soccer simulation league is one of the founding leagues of RoboCup. In this paper we discuss the past, present and planned future achievements and changes. Also we summarize the connections and inter-league achievements of this league and provide an overview of the community contributions that made this league successful.
The excessive control signaling in Long Term Evolution networks required for dynamic scheduling impedes the deployment of ultra-reliable low latency applications. Semi-persistent scheduling was originally designed for constant bit-rate voice applications, however, very low control overhead makes it a potential latency reduction technique in Long Term Evolution. In this paper, we investigate resource scheduling in narrowband fourth generation Long Term Evolution networks through Network Simulator (NS3) simulations. The current release of NS3 does not include a semi-persistent scheduler for Long Term Evolution module. Therefore, we developed the semi-persistent scheduling feature in NS3 to evaluate and compare the performance in terms of uplink latency. We evaluate dynamic scheduling and semi-persistent scheduling in order to analyze the impact of resource scheduling methods on up-link latency.
Vehicle-to-Everything (V2X) communication promises improvements in road safety and efficiency by enabling low-latency and reliable communication services for vehicles. Besides using Mobile Broadband (MBB), there is a need to develop Ultra Reliable Low Latency Communications (URLLC) applications with cellular networks especially when safety-related driving applications are concerned. Future cellular networks are expected to support novel latencysensitive use cases. Many applications of V2X communication, like collaborative autonomous driving requires very low latency and high reliability in order to support real-time communication between vehicles and other network elements. In this paper, we classify V2X use-cases and their requirements in order to identify cellular network technologies able to support them. The bottleneck problem of the medium access in 4G Long Term Evolution(LTE) networks is random access procedure. It is evaluated through simulations to further detail the future limitations and requirements. Limitations and improvement possibilities for next generation of cellular networks are finally detailed. Moreover, the results presented in this paper provide the limits of different parameter sets with regard to the requirements of V2X-based applications. In doing this, a starting point to migrate to Narrowband IoT (NB-IoT) or 5G - solutions is given.
The next generation cellular networks are expected to improve reliability, energy efficiency, data rate, capacity and latency. Originally, Machine Type Communication (MTC) was designed for low-bandwidth high-latency applications such as, environmental sensing, smart dustbin, etc., but there is additional demand around applications with low latency requirements, like industrial automation, driver-less cars, and so on. Improvements are required in 4G Long Term Evolution (LTE) networks towards the development of next generation cellular networks for providing very low latency and high reliability. To this end, we present an in-depth analysis of parameters that contribute to the latency in 4G networks along with a description of latency reduction techniques. We implement and validate these latency reduction techniques in the open-source network simulator (NS3) for narrowband user equipment category Cat-Ml (LTE-M) to analyze the improvements. The results presented are a step towards enabling narrowband Ultra Reliable Low Latency Communication (URLLC) networks.
In this paper we integrate the ideas of network coding and relays into an existing practical network architecture used in a wireless network scenario. Specifically, we use the COPE architecture to test our ideas. Since previous works have focused on the communication aspect at the physical layer level, we attempt to take it one step further by including the MAC layer. Our idea is based on information theoretic concepts developed by Shannon in order to reliably apply network coding to increase the net throughput.
Since their dawning, space communications have been among the strongest driving applications for the development of error correcting codes. Indeed, space-to-Earth telemetry (TM) links have extensively exploited advanced coding schemes, from convolutional codes to Reed-Solomon codes (also in concatenated form) and, more recently, from turbo codes to low-density parity-check (LDPC) codes. The efficiency of these schemes has been extensively proved in several papers and reports. The situation is a bit different for Earth-to-space telecommand (TC) links. Space TCs must reliably convey control information as well as software patches from Earth control centers to scientific payload instruments and engineering equipment onboard (O/B) spacecraft. The success of a mission may be compromised because of an error corrupting a TC message: a detected error causing no execution or, even worse, an undetected error causing a wrong execution. This imposes strict constraints on the maximum acceptable detected and undetected error rates.
NEXCODE is a project promoted by the European Space Agency aimed at research design development and demonstration of a receiver chain for telecomm and links in space missions including the presence of new short low-density parity-check codes for error correction. These codes have excellent performance from the error rate viewpoint but also put new challenges as regards synchronization issues and implementation. In this paper after a short review of the results obtained through numerical simulations we present an overview of the breadboard designed for practical testing and the test-plan proposed for the verification of the breadboard and the validation of the new codes and novel synchronization techniques under relevant operation conditions.
Durch den digitalen Wandel, sowie durch die an Benutzerfreundlichkeit und Leistung zunehmenden technischen Geräte im Endbenutzer-Bereich beginnt die Bedeutung von Augmented-Reality Applikationen zu wachsen. Daher ist das Ziel dieser Arbeit die Entwicklung einer Engine auf iOS Basis, zur Dastellung von Augmented-Reality Inhalten. Die Engine wurde nach dem Vorbild von Komponenten-basierten Game Engines entworfen, da diese beinahe identische Anforderungen besitzen. Die, im Rahmen dieser Arbeit erstellte Engine wurde mit Unterstützung der 5d lab Gmb entwickelt. Durch die Verwendung des, nach Erfahrungswerten, schnellsten Mobile Augmented Reality SDK und einer gelungenen Engine-Architektur konnte ein Produkt entwickelt werden, dass mit bestehenden Applikationen konkurrenzfähig ist.
The separation of nitrogen and methane from hydrogen-rich mixtures is systematically investigated on a recently developed binder-free zeolite 5A. For this adsorbent, the present work provides a series of experimental data on adsorption isotherms and breakthrough curves of nitrogen and methane, as well as their mixtures in hydrogen. Isotherms were measured at temperatures of 283–313 K and pressures of up to 1.0 MPa. Breakthrough curves of CH4, N2, and CH4/N2 in H2 were obtained at temperatures of 300–305 K and pressures ranging from 0.1 to 6.05 MPa with different feed concentrations. An LDF-based model was developed to predict breakthrough curves using measured and calculated data as inputs. The number of parameters and the use of correlations were restricted to focus on the importance of measured values. For the given assumptions, the results show that the model predictions agree satisfactorily with the experiments under the different operating conditions applied.
The objective of this thesis is the conceptual design of a battery management system for the first prototype of the UWC (University of the Western Cape) Modular Battery System. The battery system is a lithium-ion battery that aims to be used in renewable energy systems and for niche electric vehicles such as golf carts.
The concept that is introduced in this thesis comprises the parameter monitoring, the safety management and has its main focus on an accurate state of charge estimation.
Another battery system that was already implemented is used as base for the parameter monitoring and the safety management for the new battery management system. In contrast to that, the concept for the state of charge estimation must be developed completely.
Different methods for the state of charge estimation which are based on the measured voltage, current and temperature are discussed, evaluated and the chosen method is conceived in this thesis. The method used for the state of charge estimation is different for the time when the battery is active than when it is inactive. During charge and discharge Coulomb counting is used and when the cell is inactive voltage versus state of charge lookup tables are used to update the estimation.
To have an accurate estimation when the cell is inactive only for a short time, a model of the voltage relaxation is used to predict the voltage when the cells are in equilibrium. This allows the algorithm to reset the state of charge that is estimated by Coulomb counting – which tends to have a growing error over time – frequently.
To evaluate the accuracy of the voltage prediction, cell tests were executed where the voltage relaxation was sampled. The recursive least square method to predict the end voltage was tested with a MATLAB programme. With the help of voltage versus state of charge lookup tables it was possible to determine the state of charge accuracy with the accuracy of the voltage prediction.
Background: Increasing awareness of the importance of evidence-based medicine is demonstrated not only by an increasing number of articles addressing it but also by a specialty-wide evidence-based medicine initiative. The authors critically analyzed the quality of reporting of randomized controlled trials published in this Journal over a 21-year period (1990 to 2010).
Methods: A hand search was conducted, including all issues of Plastic and Reconstructive Surgery from January of 1990 to December of 2010. All randomized controlled trials published during this time period were identified with the Cochrane decision tree for identification of randomized controlled trials. To assess the quality of reporting, a modification of the checklist of the Consolidated Standard of Reporting Trials Statement was used.
Results: Of 7121 original articles published from 1990 to 2010 in the Journal, 159 (2.23 percent) met the Cochrane criteria. A significant increase in the absolute number of randomized controlled trials was seen over the study period (p < 0.0001). The median quality of these trials from 1990 to 2010 was "fair," with a trend toward improved quality of reporting over time (p = 0.127).
Conclusions: A favorable trend is seen with respect to an increased number of published randomized controlled trials in Plastic and Reconstructive Surgery. Adherence to standard reporting guidelines is recommended, however, to further improve the quality of reporting. Consideration may be given to providing information regarding the quality of reporting in addition to the "level of evidence pyramid," thus facilitating critical appraisal.
The design of control systems of concentrator photovoltaic power plants will be more challenging in the future. Reasons are cost pressure, the increasing size of power plants, and new applications for operation, monitoring and maintenance required by grid operators, manufacturers and plant operators. Concepts and products for fixed-mounted photovoltaic can only partly be adapted since control systems for concentrator photovoltaic are considerable more complex due to the required high accurate sun-tracking. In order to assure reliable operation during a lifetime of more than 20 years, robustness of the control system is one crucial design criteria. This work considers common engineering technics for robustness, safety and security. Potential failures of the control system are identified and their effects are analyzed. Different attack scenarios are investigated. Outcomes are design criteria that encounter both: failures of system components and malicious attacks on the control system of future concentrator photovoltaic power plants. Such design criteria are a transparent state management through all system layers, self-tests and update capabilities for security concerns. The findings enable future research to develop a more robust and secure control system for concentrator photovoltaics when implementing new functionalities in the next generation.
The communication system of a large-scale concentrator photovoltaic power plant is very challenging. Manufacturers are building power plants having thousands of sun tracking systems equipped with communication and distributed over a wide area. Research is necessary to build a scalable communication system enabling modern control strategies. This poster abstract describes the ongoing work on the development of a simulation model of such power plants in OMNeT++. The model uses the INET Framework to build a communication network based on Ethernet. First results and problems of timing and data transmission experiments are outlined. The model enables research on new communication and control approaches to improve functionality and efficiency of power plants based on concentrator photovoltaic technology.
How can manufacturers or service companies provide better services with connected products, without having acquired a powerful IT infrastructure nor the competences for software development?
Today companies can appeal to a relocated-IT-infrastructure provider, which is called Cloud.
Consequently, they do not have to manage and take care of the safety/security aspect, the updates and the breakdown of the infrastructure internally, as those are all managed by the provider.
It is possible to outsource the development of the software of the connected product to an external company. However, the question now is how fast this company can juggle from one Cloud to another in order to fulfil their clients wishes?
neverMind offers a solution based on a multi-protocols-platform linking the different connected products to a multitude of Clouds without having to redesign the whole communication stack/building block for each change in the Cloud-solution. This is the object of my thesis.
The development follows the V-Model, the first steps to understand the complexity of the project were the realisation of the product technical and architectural specifications. The last step before the Implementation was to design in details the progress and the process of every parts of the platform.
The outcome of the requirements analysis led me to divide the project in two parts:
• a “General Interface” acting as a gateway between the Client-application and “Cloud-modules”
• the “Cloud-modules” themselves.
So far, the specifications are drown up; the General Interface and a client example are coded, as well as a first Cloud-module template.
Zum aktuellen Zeitpunkt sind alle Sensoren einer Herz-Lungen-Maschine des Unternehmens Getinge kabelgebunden. Dadurch besteht das Risiko, dass sich während einer OP Keime auf den Kabeln sammeln, die Kabel steigern den Zeitaufwand beim Reinigen und Konnektieren und lassen das Gesamtsystem unübersichtlich wirken.
Das Ziel dieser Arbeit ist es, ein Konzept zu entwickeln, wie die Datenübertragung von einem Sensor zu einer Herz-Lungen-Maschine drahtlos erfolgen kann. Dazu wurden elf gewichtete Anforderungen an einen Funkstandard für eine drahtlose Datenübertragung definiert. Bezüglich dieser Anforderungen wurden 15 Funkstandards anhand einer Literaturrecherche analysiert. Es stellte sich heraus, dass sich ZigBee, IEEE 802.15.6, Z-Wave und EnOcean für diese Anwendung eignen, wobei ZigBee im Vergleich zu den anderen Funkstandards als am besten geeignet bewertet wurde.
Um die Eigenschaften von ZigBee bezüglich der definierten Anforderungen zu verifizieren, wurde ein ZigBee-Prototyp implementiert und getestet. Für die Bereitstellung der Mess-Funktionalität für die Tests wurde ein Programm in C++ geschrieben. Mit Hilfe dieser Tests konnte die Erfüllung der Anforderungen von ZigBee bestätigt werden.
Auf dieser Grundlage ist es möglich, die drahtlose Datenübertragung zwischen Sensor und Herz-Lungen-Maschine auf Basis des ZigBee-Funkstandards zu entwickeln. Ausblickend ist es für die Entwicklung von drahtlosen Sensoren einer Herz-Lungen-Maschine ratsam, die Akzeptanz der Anwender zu erfragen und die regulatorischen Anforderungen für Funk bei Medizinprodukten zu erläutern.
Elektrische Antriebssysteme sind in der modernen Welt überall zu finden und sind aus dem Alltag nicht mehr wegzudenken. In vielen industriellen Anwendungen wandeln sie elektrische Energie in mechanische Energie um, womit das Antriebssystem als Motor fungiert. Im umgekehrten Fall, wenn demnach mechanische Energie in elektrische Energie umgewandelt wird, arbeitet das Antriebssystem als Generator. Die dabei umgewandelte Energie soll bei einer Einspeisung in das Versorgungsnetz möglichst sinusförmig verlaufen, damit überwiegend Grundschwingungsleistung fließt. Zusätzlich ist ein geringer Blindanteil wünschenswert, weil diese Stromkomponente dafür sorgt, dass die Versorgungsleitungen unnötig belastet werden.
In dieser Bachelorthesis werden auf die für das Verständnis wichtigen theoretischen Grundlagen der Raumzeiger eingegangen. Bei der Regelung des Netz- oder Ausgangsstroms und der Zwischenkreisspannung werden auf diese Grundlagen zurückgegriffen, weil die Beschreibung von zeitveränderlichen, sinusförmig verteilten dreiphasigen Größen durch Transformationen in andere Bezugssysteme als besonders zweckmäßig erscheint. Damit weitere elektrische Geräte, die am selben Netzanschlusspunkt angeschlossen sind, möglichst wenig beeinflusst werden, sollte der ins Versorgungsnetz zurückgespeiste Strom geringe Oberschwingungen enthalten und somit einen weitestgehend sinusförmigen Verlauf annehmen.
Oberschwingungen sind ganzzahlige Vielfache der Grundschwingung der Netzfrequenz von 50 Hz. Aus regelungstechnischer Sicht ist es daher zweckmäßig, ein nahezu exaktes Modell der Regelung des Netzstroms und der Zwischenkreisspannung zu erstellen. Eine hochdynamische Regelung ist dann gewährleistet.
Entwicklung und Implementierung einer Methode zur Funktions- und Verschleißprüfung von Sägeanlagen
(2019)
Die Firma KASTO Maschinenbau produziert Lagersysteme und Sägemaschinen und möchte in Zukunft mit Hilfe von prädiktiver Wartung einen Mehrwert für den Kunden, die firmeneigenen Servicetechniker und die Inbetriebnehmer generieren. Für diesen Weg in Richtung prädiktive Wartung werden in der vorliegenden Arbeit, zunächst mittels Recherche, Grundlagen definiert. Die anschließende Analyse verschiedener Bauteile und Baugruppen in der Lagertechnik und im Sägemaschinenbau führt zur Konkretisierung der Umsetzungsmöglichkeiten.
Im weiteren Verlauf der Arbeit werden die verschleißkritischen Bauteile eines KASTOwin-Bandsägeautomats behandelt. Durch die Analyse der einzelnen Verschleißformen und -erscheinungen an dessen Komponenten können Parameter zur Verschleiß-überwachung ermittelt werden. Die Überwachung dieser Prozesse soll dabei mit bestehender Sensorik durchgeführt werden und beschränkt sich deshalb hauptsächlich auf die Messeinrichtung der Frequenzumformer. Für die Komponenten Sägebandantrieb, Sägevorschubantrieb, Materialvorschubantrieb, Bandverlaufsensor, sowie das Hydrauliksystem werden entsprechende Methoden zur Funktions- und Verschleiß-prüfung ausgearbeitet.
Auf Basis dieser Methoden wird dann die Implementierung in Form eines SPS-Programms und einer dazu passenden, grafischen Benutzeroberfläche durchgeführt. Das bestehende SPS-Programm und die Benutzeroberfläche werden durch zusätzliche Programmteile ergänzt. Sämtliche Ergänzungen sind portabel und modular ausgelegt, sodass diese problemlos auch in anderen Sägemaschinen ergänzt werden können. Um kritische Verschleißsituationen nach deren Eintritt zu analysieren und daraus Schlüsse im Sinne der prädiktiven Wartung zu ziehen, ist die Sicherung aller Langzeitdaten von enormer Bedeutung. Da der remanente Speicher der SPS jedoch begrenzt ist, werden sämtliche Daten über die Visualisierung gesichert. Alle aufgenommen Daten werden sowohl grafisch als auch in Form von Werten visualisiert und können dem Kunden und Servicetechniker, sowie dem Inbetriebnehmer Aufschluss über den Zustand der Komponenten geben.
Letztlich werden die implementierten Abläufe an einer Vorführmaschine getestet. Es kann dabei die Funktion sämtlicher Prüfungen bestätigt werden
Im Rahmen dieser Arbeit wurde ein Telepräsenzsystem entwickelt, bei dem ein Teleroboter mit beweglicher Kamera zum Einsatz kommt, der seine Ausrichtung über ein Head-mounted Display synchronisiert. Der Anwender des Systems sieht auf dem Display das Abbild der Umgebung des Teleroboters. Jede Kopfbewegung des Anwenders wird in Echtzeit auf die Kamerabewegung umgesetzt. Der Anwender kann sozusagen seinen Sehsinn temporär auf den Roboter auslagern, der ihn in einer entfernten Umgebung repräsentiert.
Electrolyte-Gated Field-Effect Transistors Based on Oxide Semiconductors: Fabrication and Modeling
(2017)
Printed electronics offers certain technological advantages over its silicon based counterparts, such as mechanical flexibility, low process temperatures, maskless and additive manufacturing process, leading to extremely low cost manufacturing. However, to be exploited in applications such as smart sensors, Internet of Things and wearables, it is essential that the printed devices operate at low supply voltages. Electrolyte gated field effect transistors (EGFETs) using solution-processed inorganic materials which are fully printed using inkjet printers at low temperatures are very promising candidates to provide such solutions. In this paper, we discuss the technology, process, modeling, fabrication, and design aspect of circuits based on EGFETs. We show how the measurements performed in the lab can accurately be modeled in order to be integrated in the design automation tool flow in the form of a Process Design Kit (PDK). We also review some of the remaining challenges in this technology and discuss our future directions to address them.
Design of next-generation cdma using orthogonal complementary codes and offset stacked spreading
(2007)
This article presents an innovative code-division multiple access system architecture that is based on orthogonal complementary spreading codes and time-frequency domain spreading. The architecture has several advantages compared to conventional CDMA systems. Specifically, it offers multiple-access-interference-free operation in AWGN channels, reduces co-channel interference significantly, and has the potential for higher capacity and spectral efficiency than conventional CDMA systems. This is accomplished by using an "offset stacked" spreading modulation technique followed by quadrature amplitude modulation, which optimizes performance in a fading environment. This new spreading modulation scheme also simplifies the rate matching algorithms relevant for multimedia services and IP-based applications.
This paper presents an overview of the coding aspects of a GNSS receiver. Coding allows detection and correction of channel-induced errors at the receiver, here the focus is on the mitigation of threats from malicious interferences. Although the effects of interference at different stages of GNSS baseband processing has been deeply analyzed in the literature, little attention was devoted to its impact on the navigation message decoding stage. Theis paper provides an introduction to the various coding schemes employed by current GNSS signals, discussing their performance in the presence of noise in terms of block-error rate. Additionally, the benefits of soft-decoding schemes for navigation message decoding are highlighted when jamming interferences are present. The proposed scheme requires estimating the noise plus interference power, yielding to enhanced decoding performances under severe jamming conditions. Finally, cryptographic schemes as a means of providing anti-spoofing for geosecurity location-based services, and their potential vulnerability are discussed, with particular emphasis on the dependence on the dependence of the scheme on successful navigation message decoding
In the brain-cell microenvironment, diffusion plays an important role: apart from delivering glucose and oxygen from the vascular system to brain cells, it also moves informational substances between cells. The brain is an extremely complex structure of interwoven, intercommunicating cells, but recent theoretical and experimental works showed that the classical laws of diffusion, cast in the framework of porous media theory, can deliver an accurate quantitative description of the way molecules are transported through this tissue. The mathematical modeling and the numerical simulations are successfully applied in the investigation of diffusion processes in tissues, replacing the costly laboratory investigations. Nevertheless, modeling must rely on highly accurate information regarding the main parameters (tortuosity, volume fraction) which characterize the tissue, obtained by structural and functional imaging. The usual techniques to measure the diffusion mechanism in brain tissue are the radiotracer method, the real time iontophoretic method and integrative optical imaging using fluorescence microscopy. A promising technique for obtaining the values for characteristic parameters of the transport equation is the direct optical investigation using optical fibers. The analysis of these parameters also reveals how the local geometry of the brain changes with time or under pathological conditions. This paper presents a set of computations concerning the mass transport inside the brain tissue, for different types of cells. By measuring the time evolution of the concentration profile of an injected substance and using suitable fitting procedures, the main parameters characterizing the tissue can be determined. This type of analysis could be an important tool in understanding the functional mechanisms of effective drug delivery in complex structures such as the brain tissue. It also offers possibilities to realize optical imaging methods for in vitro and in vivo measurements using optical fibers. The model also may help in radiotracer biomarker models for the understanding of the mechanism of action of new chemical entities.
Im Rahmen des Kontinentalen Tiefbohrprogramms der Bundesrepublik Deutschland (KTB) wurde im September 1987 in der Oberpfalz bei Windischeschenbach mit der Vorbohrung begonnen, die im Frühjahr des letzten Jahres bei einer Tiefe von 4000m erfolgreich abgeschlossen wurde. Mit der in diesem Jahr beginnenden Hauptbohrung will man 10 bis 12km tief in das Erdinnere vorstoßen. Nicht nur anhand von Gesteins- und Flüssigkeitsproben, sondern auch mit Hilfe von Meßsonden werden umfangreiche geophysikalische Daten gewonnen. Der Aufsatz beschreibt, wie die magnetische Suszeptibilität von Gesteinen bis ca. 300°C Umgebungstemperatur und einem Druck von 2kbar gemessen wird und die Daten über ein 14km langes Bohrlochkabel von der Sonde zum Steuerrechner übertragen werden.
Cardiac resynchronization therapy (CRT) with hemodynamic optimized biventricular pacing is an established therapy for heart failure patients with sinus rhythm, reduced left ventricular ejection fraction and wide QRS complex. The aim of the study was to evaluate electrical right and left cardiac atrioventricular delay and left atrial delay in CRT responder and non-responder with sinus rhythm.
Methods: Heart failure patients with New York Heart Association class 3.0 ± 0.3, sinus rhythm and 27.7 ± 6.1% left ventricular ejection fraction were measured by surface ECG and transesophageal bipolar left atrial and left ventricular ECG before implantation of CRT devices. Electrical right cardiac atrioventricular delay was measured between onset of P wave and onset of QRS complex in the surface ECG, left cardiac atrioventricular delay between onset of left atrial signal and onset of left ventricular signal in the transesophageal ECG and left atrial delay between onset and offset of left atrial signal in the transesophageal ECG.
Results: Electrical atrioventricular and left atrial delay were 196.9 ± 38.7 ms right and 194.5 ± 44.9 ms left cardiac atrioventricular delay, and 47.7 ± 13.9 ms left atrial delay. There were positive correlation between right and left cardiac atrioventricular delay (r = 0.803 P < 0.001) and negative correlation between left atrial delay and left ventricular ejection fraction (r = −0.694 P = 0.026) with 67% CRT responder.
Conclusions: Transesophageal electrical left cardiac atrioventricular delay and left atrial delay may be useful preoperative atrial desynchronization parameters to improve CRT optimization.
Private households constitute a considerable share of Europe's electricity consumption. The current electricity distribution system treats them as effectively passive individual units. In the future, however, users of the electricity grid will be involved more actively in the grid operation and can become part of intelligent networked collaborations. They can then contribute the demand and supply flexibility that they dispose of and, as a result, help to better integrate renewable energy in-feed into the distribution grids.
Experimental and theoretical investigations of the time of equalization of the concentration of an impurity in a rectangular flow‐type chamber have been carried out. It has been shown that the process of equalization of the concentration with time is exponential in character. The characteristic equalization time has been computed using the theory of turbulent diffusion. Theoretical results describe experimental regularities with an accuracy of about 10%. The value of the coefficient of turbulent diffusion for different configurations of flows in the chamber has been obtained from a comparison of experimental and calculated results.
In their famous work on prospect theory Kahneman and Tversky have presented a couple of examples where human decision making deviates from rational decision making as defined by decision theory. This paper describes the use of extended behavior networks to model human decision making in the sense of prospect theory. We show that the experimental findings of non-rational decision making described by Kahneman and Tversky can be reproduced using a slight variation of extended behavior networks.
In previous work we [1] and other authors (e.g. [2]) have shown that agent-based systems are successful in optimizing delivery plans of single logistics companies and are meanwhile successfully productive in industry. In this paper we show that agent-based systems are particularly useful to also optimize transport across logistics companies. In intercompany optimization, privacy is of major importance between the otherwise competing companies. Some data has to be treated strictly private like the cost model or the constraint model. Other data like order information has to be shared. However, typically the amount of orders released to other companies has also to be limited. We show that our agent-based approach can be easily fine tuned to trade off privacy against the benefit of cooperation.
Introduction: Cardiac resynchronization therapy (CRT) with biventricular (BV) pacing is an established therapy for heart failure (HF) patients with ventricular desynchronization and reduced left ventricular (LV) ejection fraction. The aim of this study was to evaluate electrical ventricular desynchronization with transthoracic and transesophageal signal averaging electrocardiography in HF, to better select patients for CRT.
Methods: 13 HF patients (age 68 ± 10 years; 2 females, 11 males) with New York Heart Association (NYHA) class 2.8 ± 0.5, 28.6 ± 12.6 % LV ejection fraction and 155 ± 24 ms QRS duration (QRSD) were analysed with transthoracic and transesophageal electrocardiogram recording and novel National Intruments LabView 2009 signal averaging software. Esophageal TO Osypka catheter was perorally applied to the esophagus and placed in the position of maximum LV de-flection. The 0.05-Hz high-pass filtered surface electrocardiogram and the 10-Hz high-pass filtered bipolar transesophageal electrocardiogram were recorded with Bard EP-System and 1000-Hz sampling rate.
Results: Transesophageal LV electrogram recording was possible in all HF patients (n=13). Transesophageal interventricular conduction delay (IVCD) was 51 ± 19 ms and measured between the earliest onset of QRS in the 12-channel surface electrocardiogram and the onset of the LV deflection in the transesophageal electrocardiogram. Transesophageal intra-left ventricular delay (LVCD) was 90 ± 16 ms and measured between the onset and offset of the LV deflection in the transesophageal electrocardiogram. QRSD to transesophageal IVCD ratio was 3.43 ± 1.31 ms, QRSD to transesophageal LVCD ratio was 1.75 ± 0.28 ms and QRSD was evaluated between onset and offset of QRS signal in the 12-channel surface electrocardiogram.
Conclusion: Determination of IVCD, LVCD, QRSD-to-IVCD-ratio and QRSD-to-LVCD-ratio by transesophageal LV electrogram recording with LabView 2009 signal averaging technique may be useful parameters of ventricular desynchronisation to improve patient selection for CRT.
IPv6 over resource-constrained devices (6Lo) emerged as a de-facto standard for the Internet of Things (IoT) applications especially in home and building automation systems. We provide results of an investigation of the applicability of 6LoWPAN with RPL mesh networks for home and building automation use cases. The proper selection of Trickle parameters and neighbor reachable time-outs is important in the RPL protocol suite to respond efficiently to any path failure. These parameters were analyzed in the context of energy consumption w.r.t the number of control packets. The measurements were performed in an Automated Physical Testbeds (APTB). The results match the recommendation by RFC 7733 for selecting various parameters of RPL protocol suite. This paper shows the relationship between various RPL parameters and control traffic overhead during network rebuild. Comparative measurement results with Bluetooth Low Energy (BLE) in this work showed that 6Lo with RPL outperformed BLE in this use case with less control traffic overheads.
Background: R-wave synchronised atrial pacing is an effective temporary pacing
therapy in infants with postoperative junctional ectopic tachycardia. In the technique
currently used, adverse short or long intervals between atrial pacing and ventricular
sensing (AP–VS) may be observed during routine clinical practice.
Objectives: The aim of the study was to analyse outcomes of R-wave synchronised
atrial pacing and the relationship between maximum tracking rates and AP–VS
intervals.
Methods: Calculated AP–VS intervals were compared with those predicted by experienced
pediatric cardiologist.
Results: A maximum tracking rate (MTR) set 10 bpm higher than the heart rate (HR)
may result in undesirable short AP–VS intervals (minimum 83 ms). A MTR set 20 bpm
above the HR is the hemodynamically better choice (minimum 96 ms). Effects of either
setting on the AP–VS interval could not be predicted by experienced observers. In our
newly proposed technique the AP–VS interval approaches 95 ms for HR > 210 bpm
and 130 ms for HR < 130 bpm. The progression is linear and decreases strictly
(− 0.4 ms/bpm) between the two extreme levels.
Conclusions: Adjusting the AP–VS interval in the currently used technique is complex
and may imply unfavorable pacemaker settings. A new pacemaker design is advisable
to allow direct control of the AP–VS interval.
Das Buch führt in das umfangreiche Gebiet der digitalen Bildverarbeitung ein. Neben der Hardware wie u.a. Beleuchtung, Kamera und Frame Grabber werden auch Algorithmen und Methoden beschrieben, z.B. zur Rauschunterdrückung, Bildverbesserung, Kantenextraktion und Objekterkennung usw. Die oft anspruchsvollen mathematischen Sachverhalte werden anhand von Bildbeispielen erklärt.
Orthogonal Frequency Division Multiplexing (OFDM) ist ein modernes Mehrträgermodulationsverfahren, das sich gut an die besonderen Eigenschaften eines Mobilfunkkanals mit zeitvarianter Mehrwegeausbreitung anpassen kann. Es eignet sich aufgrund seines Aufbaus vor allem für Breitbandübertragungen und wird in vielen aktuellen Funksystemen wie LTE, WLAN, DVB-T usw. eingesetzt. In DSL wird die Basisbandvariante von OFDM eingesetzt, die „Discrete Multitone Transmission (DMT)“ genannt wird. Viele Aussagen über OFDM lassen sich auch auf DMT übertragen.
Moduliert wird mit Hilfe der inversen Fouriertransformation, die viele Unterträger parallel verarbeitet und am Schluss aufsummiert. Dies hat den Nachteil einer hohen Signalfluktuation, die bei Verstärkern zu Problemen führt.
Reale Verstärker haben eine nichtlineare Verstärkungskennlinie mit einer maximalen Ausgangsamplitude. Wird diese überschritten, wird das Signal abgeschnitten (geclippt). Dies hat sowohl vermehrte Bitfehler aufgrund des Orthogonalitätsverlustets der Unterträgersignale zueinander zur Folge, als auch eine erhöhte Außerbandabstrahlung.
Eine mögliche Lösung besteht darin, die Aussteuerung des Verstärkers klein zu halten. Daraus resultieren jedoch erhöhte Kosten und eine verringerte Energieeffizienz. Man ist daher bemüht die Signalfluktuation möglichst gering zu halten. Eine Maßzahl für die Amplitudenschwankungen ist das Peak-to-Average-Power-Ratio (PAPR).
Um das PAPR zu senken, gibt es eine ganze Reihe unterschiedlicher Verfahren. In dieser Arbeit werden die gängigsten davon vorgestellt und das Interleavingverfahren, die Tone Reservations (TR) und das Active Constellation Expanding (ACE) genauer untersucht.
Printed Electronics (PE) is a promising technology that provides mechanical flexibility and low-cost fabrication. These features make PE the key enabler for emerging applications, such as smart sensors, wearables, and Internet of Things (IoTs). Since these applications need secure communication and/or authentication, it is vital to utilize security primitives for cryptographic key and identification. Physical Unclonable Functions (PUF) have been adopted widely to provide the secure keys. In this work, we present a weak PUF based on Electrolyte-gated FETs using inorganic inkjet printed electronics. A comprehensive analysis framework including Monte Carlo simulations based on real device measurements is developed to evaluate the proposed PE-PUF. Moreover, a multi-bit PE-PUF design is proposed to optimize area usage. The analysis results show that the PE-PUF has ideal uniqueness, good reliability, and can operates at low voltage which is critical for low-power PE applications. In addition, the proposed multi-bit PE-PUF reduces the area usage around 30%.
In letzter Zeit sind einige neue, hochintegrierte Einchip-Radarsensoren auf den Markt gekommen. Die enormen Fortschritte im Bereich des autonomen Fahrens hat diese Sensoren hervorgebracht. Mit ihnen lassen sich diverse Anwendungen, wie zum Beispiel eine Abstandsmessung, Kollisionserkennung oder Geschwindigkeitserfassung realisieren.
Für die Nutzung eines solchen modernen Radarsensors spricht viel, jedoch besitzen alle eine differenzielle Ausgangsschnittstelle, die nicht mit den üblichen Mikrocontrollersystemen eingelesen werden kann. Darum war das Ziel der Arbeit, die Entwicklung eines Schnittstellenwandlers auf einem Low-Power-FPGA, zur Anbindung eines Radarchips an einen klassischen Mikrocontroller.
Der Lösungsweg war demnach schon vorgegeben, es folgte die konkrete Umsetzung mit der Modellierung der Hardware in VHDL. Der FPGA liest die differenzielle Schnittstelle ein, parallelisiert die Daten und speichert sie zwischen. Sobald die Messdaten vollständig sind, können sie über die serielle SPI-Schnittstelle angefordert werden. Als Gegenstelle kommt ein Mikrocontroller zum Einsatz, der die Messdaten wiederum gemäß eines definierten Protokolls zur Auswertung an einen Computer weiterleitet.
Die Machbarkeit dieser Anwendung wurde kontrolliert, indem die Messdaten vom Radarchip, übermittelt durch den FPGA und Mikrocontroller, auf dem Computer mithilfe eines Analyseprogramms bewertet wurden. Die Auswertung der Messergebnisse entspricht in vollem Umfang den Erwartungen. Der Ressourcenverbrauch im FPGA wurde hierbei ebenfalls als kritisch betrachtet, was sich im Nachhinein jedoch nicht bestätigte. Es ist sogar das Gegenteil der Fall, mit den übrigen freien Ressourcen steht einer möglichen Signalverarbeitung nichts im Wege.
A new approach of continuous phase QPSK Band-Pass modulation technique is being developed as enhancement to the QPSK modulation scheme for inductive data transmission (NFC). The modulation is based on Gaussian filtering of the phase transition from one state to the other rather than discontinuity in phase shift. The carrier is based on low frequency 115 KHz suitable for human body energy penetration due to its large skin-depth and lower inductive power attenuation. The complete signal processing is done digitally, external coil and capacitor is used for transceiver interface. The telemetry assists a smart pill swallowed by human being to trigger an actuator for drug delivery, record temperature, or perform diagnostic task inside the body. The smart pill includes 32bit processor, 16 Kbyte memory, temperature sensor, telemetry unit, and additional external peripheries. The complete system is designed, embedded in one SoC, and realized on ASIC with chip-area less than 14 mm<sup>2</sup>.
Nowadays the processing power of mobile phones, smartphones and PDAs is increasing as well as the transmission bandwidth. Nevertheless there is still the need to reduce the content and the need of processing the data. We discuss the proposals and solutions for dynamic reduction of the transmitted content. For that, device specific properties are taken into account, as much as for the aim to reduce the need of processing power at the client side to be able to display the 3D (virtual reality) data. Therefore, well known technologies, e.g. data compression are combined with new developed ideas to reach the goal of adaptive content transmission. To achieve a device dependant reduction of processing power the data have to be preprocessed at the server side or the server even has to take over functionality of weak mobile devices.
Das Team "magmaOffenburg" nimmt seit 2009 an der 3D-Simulationsliga des RoboCups teil. Wie gut das Laufen auf zwei Beinen in der verwendeten Simulationsumgebung "SimSpark" funktioniert ist einer der zentralen Faktoren für ein erfolgreiches Abschneiden. Bisher wird für das Laufen ausschließlich eine inverskinematische Walk-Engine verwendet.
In dieser Arbeit wird mit genetischen Algorithmen und einer modellfreien Parametrisierung Laufen komplett "from scratch" gelernt. Derselbe Ansatz wurde zuvor bereits erfolgreich für das Lernen von Kicks eingesetzt. Gegenüber der alten Walk-Engine zeichnet diesen Ansatz besonders aus, dass zum ersten Mal die Zehengelenke genutzt werden, welche eines der verfügbaren Robotermodelle besitzt. Dies ermöglicht einen natürlicheren und schnelleren Gang. Zwar ist die Stabilität des gelernten Laufens noch nicht vergleichbar mit dem bisherigen (der Spieler fällt etwa 26% häufiger hin), aber beispielsweise beim Vorwärtslaufen konnten mit einer Geschwindigkeit von 1.3 m/s statt 1 m/s Steigerungen von 30% erzielt werden.
Darüber hinaus wurde untersucht, wie dem Agenten im Anschluss an das gelernte Laufen wieder ein Übergang zur alten Walk-Engine gelingen kann. Der erfolgreichste Ansatz basiert ebenfalls wieder auf einer mit genetischen Algorithmen trainierten Bewegung. Er ist in etwa der Hälfte der Fälle erfolgreich.
This paper treats the interaction between acoustic modes and light (Brillouin scattering) in a single mode optical fibre. Different observed spectra of the Brillouin backscattering in several fibres have been already reported. In order to have a clear idea of the process, we made a simulation to be able to `draw' the theoretical Brillouin spectrum of an optical fibre and to identify the origin of the observed backscattered lines.
First, the model and the computation method used in our simulation are described. Second, the experimentally observed spectra of two real fibres are compared with their computed spectra. Real spectra and simulated spectra are in good agreement.
Our work provides an interesting tool to investigate the changes in the Brillouin spectrum when the input parameters (characteristics of an optical fibre) vary. This should give useful indications to people working on systems which use Brillouin backscattering.
Diese Bachelorarbeit untersucht die Möglichkeiten der Persistierung und anschließenden Analyse verschiedener Messwerte in einer geeigneten Software-Architektur. Zunächst wird dazu die genaue Aufgabenstellung betrachtet. Im Anschluss soll die geplante Software-Architektur und die vorgesehene Kommunikationsart erklärt werden. Um das entwickelte Produkt einfach zur Verfügung stellen zu können, sollen die Tools Vagrant, Puppet und Docker gemeinsam genutzt werden. Nachdem im Anschluss auf die eingesetzte Servertechnologie eingegangen wurde, beschäftigt sich die Arbeit mit der Persistierung der Messdaten. Hierzu werden die verschiedenen Arten verfügbarer Datenbanktechnologien erläutert und darauf aufbauend eine Auswahl getroffen. Als letzten Teil der Anwendung wird auf die Demonstrationsapplikation eingegangen. Hier werden wieder die nötigen Anforderungen erörtert und die Umsetzung beschrieben.
Anhand der gewonnenen Erkenntnisse wird abschließend ein Fazit der verwendeten Technologien und der Architektur verfasst. Hier soll die Eignung der verwendeten Technologien zur Lösung des Problems überprüft und bewertet werden.
Abschließend wird noch ein Ausblick auf die zukünftige Entwicklung in diesem Bereich gegeben.
The instability of ultra-thin films of an electrolyte bordering a dielectric gas in an external tangential electric field is scrutinized. The solid wall is assumed to be either a conducting or charged dielectric surface. The problem has a steady one-dimensional solution. The theoretical results for a plug-like velocity profile are successfully compared with available experimental data. The linear stability of the steady-state flow is investigated analytically and numerically. Asymptotic long-wave expansion has a triple-zero singularity for a dielectric wall and a quadruple-zero singularity for a conducting wall, and four (for a conducting wall) or three (for a charged dielectric wall) different eigenfunctions. For infinitely small wave numbers, these eigenfunctions have a clear physical meaning: perturbations of the film thickness, of the surface charge, of the bulk conductivity, and of the bulk charge. The numerical analysis provides an important result: the appearance of a strong short-wave instability. At increasing Debye numbers, the short-wave instability region becomes isolated and eventually disappears. For infinitely large Weber numbers, the long-wave instability disappears, while the short-wave instability persists. The linear stability analysis is complemented by a nonlinear direct numerical simulation. The perturbations evolve into coherent structures; for a relatively small external electric field, these are large-amplitude surface solitary pulses, while for a sufficiently strong electric field, these are short-wave inner coherent structures, which do not disturb the surface.
This thesis deals with the creation of a cross-platform application using Xamarin.Forms. The cross-platform application will cover three different platforms android, iOS, and UWP.
The application is the first concept of a possible feature for a companion application for LS telcom. There, the user can identify cell antennas using a map-view and a camera-view making the application an augmented reality application. Thus, the user can search for a specific cell and access various information that he would not be able to see with his eyes like for example the frequency of the transmitting cells.
The cell data is generated from three different sources, Cartoradio, OpenCelliD, and the LS telcom databrowser. Eventually, the decision was taken, that the main source should be the LS telcom databrowser which has multiple advantages over the other cell sources.
The cells on the map-view are placed using the extracted coordinates from the source data. However, the cells on the camera-view are placed with complex calculations using different formulas like the Haversine formula to calculate the distance between the cell and the user and the bearing to calculate the angle between the cell and the user. Various settings will allow the user to personalize the application according to his wishes.
Oxide semiconductors are highly promising candidates for the most awaited, next-generation electronics, namely, printed electronics. As a fabrication route for the solution-processed/printed oxide semiconductors, photonic curing is becoming increasingly popular, as compared to the conventional thermal curing method; the former offers numerous advantages over the latter, such as low process temperatures and short exposure time and thereby, high throughput compatibility. Here, using dissimilar photonic curing concepts (UV–visible light and UV-laser), we demonstrate facile fabrication of high performance In2O3 field-effect transistors (FETs). Beside the processing related issues (temperature, time etc.), the other known limitation of oxide electronics is the lack of high performance p-type semiconductors, which can be bypassed using unipolar logics from high mobility n-type semiconductors alone. Interestingly, here we have found that our chosen distinct photonic curing methods can offer a large variation in threshold voltage, when they are fabricated from the same precursor ink. Consequently, both depletion and enhancement-mode devices have been achieved which can be used as the pull-up and pull-down transistors in unipolar inverters. The present device fabrication recipe demonstrates fast processing of low operation voltage, high performance FETs with large threshold voltage tunability.
Die Funkschnittstelle nach dem Bluetooth Standard ist heutzutage nicht mehr aus dem Consumer-Markt wegzudenken. Auch durch die zukünftige Weiterentwicklung des Prinzips von IoT (Internet of Things) wird vor allem die Bluetooth Low Energy Technologie für Unternehmen bei der Entwicklung von Geräten mehr an Bedeutung gewinnen. Um die Studierenden im Bereich der Kommunikationstechnik auf das Thema Bluetooth vorzubereiten, wird der Versuch „Kurzstreckenkommunikation nach dem Bluetooth Standard“ im Telekommunikations-Labor an der Hochschule Offenburg angeboten. Der Versuch wurde im Rahmen dieser Bachelor-Thesis an die heutigen Anforderungen angepasst.
Die nachfolgende Bachelor-Thesis beinhaltet die gesamte Laboranleitung des Versuchs, welche in die drei Teile: Theoretische Grundlagen, vorbereitende Aufgaben und der Versuchsdurchführung aufgeteilt wird. Der Versuchsanleitung folgt ein Teil mit weiteren Anmerkungen für die akademischen Mitarbeiter, welche den Versuch betreuen. Hier wird sichergestellt, dass auch in Zukunft der Versuch problemlos weiter durchgeführt werden kann. Im Anhang befinden sich die Musterlösungen für die vorbereitentenden Aufgaben und der Versuchsdurchführung.
Das Ziel der vorliegenden Bachelorarbeit war es, ein Anforderungsprofil für den Aufbau eines Messsystems im Hochspannungsnetz der DB Energie zu entwickeln. Dieses soll als Basis für den künftigen Aufbau des Systems dienen und die Besonderheiten des 110 kV, 16,7 Hz Netzes berücksichtigen. Die Ziele des Messsystems sind es, Aussagen über den Betriebszustand des Netzes mit resonanter Sternpunkterdung, hinsichtlich der Netzstabilität, der Erdschlusslöschfähigkeit und dem Erzeugerverhalten, treffen zu können.
Dazu wurden Experteninterviews durchgeführt, die die Anforderungen an das Messkonzept definieren. Darauf aufbauend wurden die geforderten Messungen und Auswertungen hinsichtlich der Umsetzbarkeit im Netz der DB Energie überprüft. Besonderes Augenmerk lag auf den verbauten Strom- und Spannungswandler im Netz, an denen die entsprechenden Messgrößen abgegriffen werden sollen. Deren Abbildungstreue, in Bezug auf die Genauigkeit des Messwerts und das Transferverhalten bei unterschiedlichen Frequenzen, wurde eingehender betrachtet.
Ebenfalls wurde die bei den Messungen aufkommenden Datenmengen näher betrachtet. Die Art der Messung und Auswertung der Daten sind hier ausschlaggebend, um die Daten klein zu halten. Die Empfehlung ist ein Kompromiss aus zwei gleichzeitig ablaufenden Auswertungen, um die anfallenden Datenmengen gut und schnell analysieren zu können.
This paper investigates the maximum torque capability and torque ripple reduction using the asymmetric stator teeth for interior permanence magnet (IPM) synchronous machines. Traditional electric machines have the identical width for all stator teeth and the winding function is fixed. Using different widths for different stator teeth changes the winding function, therefore, the torque ripple components. The mathematical modeling of interior permanent magnet (IPM) synchronous machine torque ripple and finite element analysis simulation results for the characteristic properties of electric machines are presented. Compared with a similar rating IPM machine, certain combinations of the teeth widths can reduce the torque ripple by 80% with less than 4% average torque decline.
This paper discusses a technological solution to real-time road transportation optimization using a commercial multi-agent based system, LS/ATN, which has been proven through real-world deployment to reduce transportation costs for both small and large fleets in the full and part load business. Subsequent to describing the real-time optimization approach, we discuss how the platform is currently evolving to accept live data from vehicles in the fleet in order to improve optimization accuracy. A selection of the predominant pervasive technologies available today for enhancing intelligent route optimization is described.
Im ersten Teil der vorliegenden Master-Thesis geht es um die Entwicklung einer Low-Power Wireless-Lichtschranke. Der Hardware-Aufbau wird ausführlich beschrieben und Besonderheiten für die Low-Power-Auslegung, wie beispielsweise Power-Management, werden vorgestellt. Optische Einheiten, Power-Management-Einheiten, System-On-Chip und Funkstufe werden ausführlich angesprochen. Die interrupt-gesteuerte und zeitlich optimierte Programmierung wird im Anschluss an den Hardware-Aufbau vorgestellt. Auch hier werden Low-Power-Eigenschaften diskutiert. Die Anbindung der Lichtschranke an einen Hub im 868 MHz ISM Band (engl.: Industrial, Scientific and Medical Band) und die Datenübertragung mittels Bluetooth an einen Computer, sowie die Programmierung einer Anzeige-GUI zur Visualisierung der Funkdaten mit LabVIEW werden weiterführend behandelt. Ergänzend hierzu wird die entwickelte Hardware vermessen und charakterisiert. Die Messergebnisse werden ausgewertet und vorgestellt.
Im zweiten Teil der Master-Thesis geht es um die Entwicklung eines Schulungskonzepts. In der Sick AG halten sich alle Abteilungen (Divisions) beim Entwickeln eines Produktes an einen vorgegebenen Produktentstehungsprozess. Division 1 hat im Rahmen dieses Produktentstehungsprozesses eine Konkretisierung vorgenommen: den Masterplan. Für die Einführung des Masterplans wurde ein teilnehmerorientiertes Schulungskonzept entwickelt. Es wird zuerst auf die Inhalte eingegangen. Im Anschluss werden die Teilnehmer untersucht und Motive und Lernvoraussetzungen charakterisiert. Nachdem diese und weitere Rahmenbedingungen geklärt sind, wird ein didaktisch durchdachtes Schulungskonzept entwickelt, ausführlich vorgestellt und diskutiert.
Lithium-oxygen cells with organic electrolyte suffer high overpotentials during charge, indicating asymmetric charge/discharge reaction mechanisms. We present a multi-physics dynamic modeling and simulation study of the Li/O2 cell cycling behavior. We present three different multi-step mechanisms of the 2 Li + O2 ⇄ Li2O2 cell reaction, (A) a reversible 5-step mechanism, (B) a partially irreversible 6-step mechanism, and (C) a partially irreversible 8-step mechanism that includes reactions of a redox mediator. Model predictions are compared to experimental galvanostatic cycling data of Swagelok cells without and with 2,2,6,6-tetramethylpiperidinyloxyl (TEMPO) as redox mediator. All mechanisms are able to predict the discharge behavior in good agreement to the experimental results. The experimentally observed high charge overpotentials as well as their reduction by using a redox mediator can be qualitatively reproduced with the irreversible reaction mechanisms. However, the particular shape of the experimental charge curve with continuously increasing charge overpotential cannot be reproduced with the present mechanisms.
Ziel dieser Bachelorarbeit war es, die Motoren einer parallelen Kinematik in Form eines Tripods anzusteuern, um den Endeffektor präzise an bestimmte Positionen zu bewegen. Dadurch wurde getestet, ob sich die Steuerung eines chirurgischen Instrumentes über eine parallele Kinematik prinzipiell für den Einsatz in der klinischen Umgebung eignen würde. Der Tripod umfasst drei Linearachsen, deren Längen und Winkel durch die Motoren geändert werden können. Alle drei Linearachsen sind über Kugelgelenke an den Endeffektor gekoppelt. Für die Ansteuerung der Motoren musste sowohl eine Elektronik, als auch eine Software entwickelt werden, die die Kommunikation zwischen den Motoren und einem Computer ermöglichen. Für die Entwicklung der Software wurde die objektorientierte Programmiersprache C++ genutzt. Durch das implementierte C++-Programm können beliebige Positionen an die Motoren gesendet werden, zu denen der Endeffektor daraufhin bewegt wird. Zudem ermöglicht das Programm die individuelle Echtzeit-Steuerung des Endeffektors über eine 3D-Maus mit sechs Freiheitsgraden. Für die Umrechnung der räumlichen Daten der 3D-Maus in die einzelnen Zielpositionen für die Motoren wurde eine Klasse, speziell für diesen Tripod, implementiert. Aufgrund dieser Klasse und der Optimierung von Geschwindigkeit und Beschleunigung der Motoren lässt sich der Endeffektor präzise und flüssig steuern. Die sensitive Steuerung eines chirurgischen Instrumentes wird dadurch ermöglicht, für den Einsatz in einer klinischen Umgebung ist der Tripod aufgrund der Größe und Handhabung jedoch nicht geeignet. Dafür wäre eine Miniaturisierung dieser parallelen Kinematik erforderlich.
Introduction: Cardiac resynchronization therapy (CRT) with biventricular (BV) pacing is an established therapy for heart failure (HF) patients with ventricular desynchronisation and reduced left ventricular (LV) function. The aim of this study was to evaluate preejection period (PEP) and left ventricular ejection time (LVET) with transthoracic signal averaging impedance and electrocardiography in HF patients with and without BV pacing.
Methods: 10 HF patients (age 68.9 ± 8 years; 2 females, 9 males) with New York Heart Association (NYHA) class 2,9 ± 0.5, 30.9 ± 10.5 % LV ejection fraction and 159.4 ± 22.9 ms QRS duration were analysed with transthoracic impedance and electrocardiography (Cardioscreen Medis, Ilmenau, Germany) and novel National Intruments LabView 2009 signal averaging software. One day after BV pacing device implantation, AV and VV delays were optimized by transthoracic impedance cardiography and stroke volume (SV) and cardiac output (CO) were gained by Cardioscreen.
Results: Transthoracic impedance and electrocardiography AV and VV delay opimization was possible in all HF patients with BV pacing devices (n= 10). PEP was 154 ± 24ms without BV pacing and measured between onset of QRS in the surface electrocardiogram and onset of ventricular deflection in the impedance cardiogram. LVET was 342 ± 65ms without BV pacing and measured between onset and offset of ventricular deflection in the impedance cardiogram. The use of optimal AV and VV delay BV pacing resulted in improvement of SV from 64.1 ± 26.5 ml to 94.1 ± 33.96 ml (P < 0.05) and CO from 4.05 ± 1.36 l/min to 6.44 ± 1.56 l/min (P < 0.05).
Conclusion: PEP and LVET may be useful parameters of ventricular Desynchronisation. AV and VV delay optimized BV pacing improve SV and CO. Impedance and electrocardiography with LabView 2009 signal averaging may be a simple and useful technique to optimize CRT.
Introduction: Cardiac resynchronization therapy (CRT) with biventricular pacing is an established therapy for heart failure (HF) patients with sinus rhythm and ventricular desynchronisation. The aim of this study was to evaluate interventricular conduction delay (IVCD) and interatrial conduction delay (IACD) before and after premature ventricular contractions (PVC) in HF patients.
Methods: 13 HF patients (age 68 ± 10 years; 2 females, 11 males) with New York Heart Association functional class 2,8 ± 0.5, left ventricular (LV) ejection fraction 28,6 ± 12,6 %, 154 ± 25 ms QRS duration and PVC were analysed with bipolar transesophageal LV and left atrial electrogram recording and National Instruments LabView 2009 software. The level of significance of the t-test is 0,005.
Results: QRS duration increases during PVC (188 ± 32 ms) in comparison to the beat before (154 ± 25 ms, P = ) and after PVC (152 ± 25 ms,). IVCD increases during PVC up to 65 ± 33 ms (51 ± 19 ms in the beat before PVC, P=0.18, 49 ± 19 ms after PVC, P = 0.12). Intra-LV delay of 90 ± 16 ms is not different in the beat before PVC, 90 ± 14 ms during PVC (P = 0.99) and 94 ± 16 ms in the beat after PVC (P = 0.38). IACD is not significantly PVC influenced (67 ± 12 ms before PVC and 65 ± 13 ms after PVC, P = 0.71). Intra-left atrial conduction delay is not significant longer during PVC (57 ± 28 ms) than in the beat before PVC (54 ± 13 ms, P = 0.51) or after PVC (54 ± 8 ms, P = 0.45). PQ duration increases significantly after PVC (224 ± 95 ms) in comparison to the beat before PVC (176± 29 ms, P =...).
Conclusion: Transesophageal left cardiac electrocardiography with LabView 2009 software can improve evaluation of IVCD and IACD before, during and after PVC in HF patient selection for CRT.
Data Mining of the Edge
(2016)
Kleine, intelligente Systeme prägen zunehmend unsere Umwelt, dass sogenannte Internet of Things wird immer mehr Teil unseres Alltages. Diese Geräte sind immer mehr dazu in der Lage Daten aufzunehmen und zu verarbeiten. Doch wie jede Technische Revolution, führt auch der Ausbau des IoT zu neuen Herausforderungen. Das Ziel dieser Arbeit ist die Bewertung der Qualität von verschiedenen Data Mining Frameworks im Edge Bereich, die Erstellung mehrere Demonstatoren eines Edge Szenario Aufbaus sowie deren Evaluation.
Pressure dynamics in metal-oxygen (metal-air) batteries: a case study on sodium superoxide cells
(2014)
Electrochemical reactions in metal–oxygen batteries come along with the consumption or release of gaseous oxygen. We present a novel methodology for investigating electrode reactions and transport phenomena in metal–oxygen batteries by measuring the pressure dynamics in an enclosed gas reservoir above the oxygen electrode. The methodology is exemplified by a room-temperature sodium–oxygen battery forming sodium superoxide (NaO2) in an electrolyte of diethylene glycol dimethyl ether (diglyme) and sodium trifluoromethanesulfonate (NaOSO2CF3, NaOTf). The experiments are supported by microkinetic simulations with a one-dimensional multiphysics continuum model. During galvanostatic cycling over 30 cycles, a constant oxygen consumption/release rate is observed upon discharge/charge. The number of transferred electrons per oxygen molecule is calculated to 1.01 ± 0.02 and 1.03 ± 0.02 for discharge and charge, respectively, confirming the nature of the oxygen reaction product as superoxide O2–. The same ratio is observed in cyclic voltammetry experiments with low scan rate (<1 mV/s). However, at higher scan rates, the ratio increases as a result of oxygen transport limitations in the electrolyte. We introduce electrochemical pressure impedance spectroscopy (EPIS) for simultaneously analyzing current, voltage, and pressure of electrochemical cells. Pressure recording significantly increases the sensitivity of impedance toward oxygen transport properties of the porous electrode systems. In addition, we report experimental data on the diffusion coefficient and solubility of oxygen in electrolyte solutions as important parameters for the microkinetic models.
Die Mismatch Negativity (MMN) bezeichnet eine Komponente reizkorrelierter Potentiale. Die MMN ist ein negativer Potentialkomplex, der ungefähr 100 bis 300 ms nach Stimuluspräsentation auftritt, wenn ein neuer Stimulus im Vergleich zu zuvor präsen-tierten, gleichartigen Stimuli ausreichend bzgl. Frequenz, Dauer, Ort oder Intensität abweicht. Der MMN zu Grunde liegen Messungen der späten akustisch evozierten Po-tentiale (SAEP). Die von beiden Stimuli hervorgerufenen SAEP werden separat gemittelt. Bei ausreichender Differenz der Stimuli und geeigneter Stimulusabfolge ist eine Potentialdifferenz zwischen den beiden gemittelten Antworten ableitbar, die MMN.
In dieser Arbeit wurde die Ableitung der MMN mit dem Registriersystem Eclipse EP-25 der Firma Interacoustics in Bezug auf zwei Stimulustypen, Tone-Bursts und Sprach-laute, evaluiert.
Der stetige technische Fortschritt in der Strahlentherapie stellt eine erhöhte Herausforderung bei der Bestimmung von dosimetrischen Parametern dar, die besonders in kleinen Bestrahlungsfeldern einen hohen Grad an Unsicherheit aufweisen. Es wurden die Tiefendosiskurve sowie Dosisquerprofile unterschiedlicher Dosimeter in dosimeterabhängigen Ausrichtungen bei Photonenstrahlung von 6 MV gemessen. Parameter wie die relative Oberflächendosis, das Tiefendosismaximum, die relative Dosis in 5 und 10 cm Tiefe sowie die Penumbrabreite verschiedener Dosimeter wurden miteinander verglichen. Die Messungen erfolgten je Dosimeter bei 10, 6, 4, 3, 2, 1 und 0,6 cm Kantenlänge bei quadratischen Bestrahlungsfeldern.
Beim Dosisquerprofil der Semiflex Typ 31013 mit 0,3 cm³ Messvolumen ergeben die Messwerte nicht ausreichend genaue Ergebnisse. Unter denselben Messbedingun-gen mit der Dosimeter-Diode E ergibt die relative Dosis innerhalb des Strahlenfeldes ausreichend genaue Messwerte, die zur Auswertung bereitstehen. Die Penumbrabreite verringert sich mit geringerem Messvolumen sowie auch im kleineren Bestrahlungsfeld. Die relative Dosis in der Tiefe nimmt mit kleiner werdendem Bestrahlungsfeld und ebenso mit entsprechend kleinen Messvolumina ab. Die Überreaktion der PinPoint auf niederenergetische Photonen muss berücksichtigt werden, um ausreichend genaue Messergebnisse zu erhalten. Wird dieser Dosimeter radial bestrahlt, zeigen die Dosisquerprofile aufgrund des Kabeleffekts eine schlechtere Symmetrie der quadratischen Bestrahlungsfläche auf.
Die Wasserenergiedosis weist in kleinen Bestrahlungsfeldern deutliche Unterschiede bei den unterschiedlichen Dosimetern auf. Zwischen dem Dosimeter mit dem größten Messvolumen und dem mit dem kleinsten besteht ein Messwertunterschied von 0,5 Gy.
Cardiac resynchronization therapy (CRT) is an established class I level A biventricular pacing therapy in chronic heart failure patients with left bundle branch block and reduced left ventricular ejection fraction, but not all patients improved clinically. Purpose of the study was to evaluate electrical interatrial conduction delay (IACD) to interventricular conduction delay (IVCD) ratio with focused transesophageal left atrial and left ventricular electrocardiography.
Methods: Thirty eight chronic heart failure patients (age 63.4±10.2 years; 3 females, 35 males) with New York Heart Association (NYHA) functional class 3.0±0.2 and 171.71±36.17ms QRS duration were analysed using posterior left atrial and left ventricular transesophageal electrocardiography with hemispherical electrodes before CRT. Electrical IACD was measured between onset of P-wave in the surface ECG and onset of left atrial signal. Electrical IVCD was measured between onset of QRS complex in the surface ECG and onset of left ventricular signal.
Results: Electrical IACD and IVCD could be evaluated by transesophageal left atrial and left ventricular electrocardiography in all heart failure patients with correlation to 1.18±0.92 IACD-IVCD-ratio (r=-0.57, P<0.001; r=0.66, P<0.001). There were 32 CRT responder with reduction of NYHA class from 3.0±0.22 to 1.97±0.31 (P<0.001) during 16.5±18.9 month CRT with 75.19±33.49ms IACD, 78.91±24.73ms IVCD, 1.04±0.66 IACD-IVCD-ratio and correlation between IACD and IACDIVCD- ratio (r=0.84, P<0.001). There were 6 CRT nonresponder with no reduction of NYHA class from 3.0±0.3 to 2.9±0.5 during 14.3±13.7 month biventricular pacing, 50.0±28.26ms IVCD (P=0.014), 1.92±1.65 IACD-IVCD-ratio (P=0,029) and correlation between 67.0±24.9ms IACD and IACD-IVCD-ratio (r=0.85, P=0.031).
Conclusions: Focused transesophageal left atrial and left ventricular electrocardiography can be utilized to analyse electrical IACD and IVCD in heart failure patients. IACDIVDC- ratio may be a useful parameter to evaluate electrical left cardiac desynchronization in heart failure patients.
Cardiac resynchronization therapy (CRT) with biventricular pacing (BV) is an established therapy for heart failure (HF) patients with inter- and intraventricular conduction delay. The aim of this pilot study was to test the feasibility of both transesophageal measurement of left ventricular (LV) electrical delay and transesophageal LV pacing prior to implantation, to better select patients for CRT.
Introduction: Cardiac resynchronization therapy (CRT) with biventricular pacing (BV) is an established therapy for heart failure (HF) patients (P) with ventricular desynchronisation, but not all patients improved clinically. Aim of this study was to evaluate electrical intra-left ventricular conduction delay (LVCD) and interventricular conduction delay (IVCD), to better select patients for CRT.
Methods: 65 HF patients (age 63.4 ± 10.6 years; 7 females, 58 males) with New York Heart Association (NYHA) class 3 ± 0.2, 24.4 ± 6.7 % left ventricular (LV) ejection fraction and 167.4 ± 35.6 ms QRSD were included. Esophageal TO Osypka focused hemispherical electrodes catheter was perorally applied in position of maximum LV deflection to measure LVCD between onset and offset of LV deflection and IVCD between earliest onset of QRS in the 12-channel surface ECG and onset of LV deflection in the focused bipolar transesophageal LV electrogram.
Results: There were 50 responders with LVCD of 76.5 ± 20.4 ms, IVCD of 80.5 ± 26.1 ms (P=0.34) and QRSD of 171 ± 37.7 ms. 15 non-responders had longer LVCD of 90 ± 28.5 ms (P = 0.045), shorter IVCD of 50.1 ± 29.1 ms (P < 0.001) and QRSD of 155.3 ± 25 ms (P=0.14). During 21.3 ± 20.3 month BV pacing follow-up, the responder`s NYHA classes improved from 3 ± 0.2 to 2. ± 0.3 (P < 0.001) whereas the non-responders NYHA classes did not improve from 3 ± 0.2 to 2.9 ± 0.3 (P = 0.43) during 15.7 ± 13.9 month BV pacing follow-up (53 Boston, 10 Medtronic and 2 St. Jude CRT devices).
Conclusion: Determination of electrical LVCD and IVCD by focused bipolar transesophageal LV electrogram recording may be an additional useful technique to improve patient selection for CRT.
Introduction: Cardiac resynchronisation therapy (CRT) with atrioventricular (AV) and interventricular (VV) optimized biventricular pacing (BV) is an established therapy for heart failure (HF) patients. The aim of the study was to compare AV and VV delay optimization with cardiac output (CO), cardiac index (CI), contractility index (IC) and acceleration index (ACI) impedance cardiographic (ICG) methods in CRT.
Methods: 15 HF patients (age 66 ± 10 years; 2 females, 13 males) in New York Heart Association (NYHA) class 3.1 ± 0.4, left ventricular (LV) ejection fraction 21.3 ± 7.8 % and QRS duration 176.1 ± 31.7 ms underwent AV and VV delay optimization with CO, CI, IC and ACI (Cardioscreen ®, Medis GmbH, Ilmenau, Germany) at different AV and VV delay BV pacing settings versus right ventricular (RV) pacing one day after implantation of a CRT device.
Results: Optimal AV delay after atrial sensing was 108.6 ± 20.3 ms (n=14) and optimal AV delay after atrial pacing 190 ± 14.1 ms (n=2) with AV delay range from 80 ms to 200 ms. Optimal VV delay was -12.3 ± 25.9 ms left ventricular before RV pacing. RV versus BV pacing mode resulted in improvement of CO from 3.4 ± 1.2 l/min to 4.4 ± 1.4 l/min (p<0.001), CI from 1.8 ± 0.64 l/min/m² to 2.4 ± 0.78 l/min/m² (p<0.001), IC from 0.028 ± 0.011 1/s to 0.036 ± 0.013 1/s (p<0.001) and ACI from 0.667 ± 0.227 1/s² to 0.834 ± 0.282 1/s² (p<0.002). During 34 ± 26 month BV pacing, the NYHA class improved from 3.1 ± 0.4 to 2.1 ± 0.4 (p<0.001).
Conclusion: AV and VV delay optimized BV pacing acutely improve hemodynamic parameters of transthoracic ICG and their NYHA class during long-term follow-up. ICG may be a simple and useful technique to optimize AV and VV delay in CRT.
Introduction: Cardiac resynchronisation therapy (CRT) with atrioventricular (AV) and interventricular (VV) optimized biventricular pacing (BV) is an established therapy for heart failure (HF) patients with electrical interventricular conduction delay (IVCD). The aim of the study was to compare AV and VV delay optimization with cardiac output (CO) and acceleration index (ACI) impedance cardiographic (ICG) methods.
Methods: HF patients with IVCD 86.8 ± 33 ms (n=15, age 66 ± 10 years; 2 females, 13 males), New York Heart Association (NYHA) functional class 3.1 ± 0.4, left ventricular (LV) ejection fraction 21.3 ± 7.8 % and QRS duration 176.1 ± 31.7 ms underwent AV and VV delay optimization with CO and ACI methods (Cardioscreen, Medis GmbH, Ilmenau, Germany). After evaluation of optimal AV delay, we evaluated optimal VV delay during simultaneous LV and right ventricular (RV) pacing (LV=RV), LV before RV pacing (LV-RV) and RV before LV pacing (RV-LV).
Results: Optimal VV delay was -12.3 ± 25.9 ms LV-RV pacing with VV delay range from -80 ms LV-RV pacing to +20 ms RV-LV pacing and RV=LV pacing. Optimal AV delay after atrial sensing was 108.6 ± 20.3 ms (n=14) and optimal AV delay after atrial pacing 190 ± 14.1 ms (n=2) with AV delay range from 80 ms to 200 ms. RV versus BV pacing mode resulted in improvement of CO from 3.4 ± 1.2 l/min to 4.4 ± 1.4 l/min (p<0.001) and ACI from 0.667 ± 0.227 1/s² to 0.834 ± 0.282 1/s² (p<0.002). During 34 ± 26 month BV pacing, the NYHA class improved from 3.1 ± 0.4 to 2.1 ± 0.4 (p<0.001).
Conclusion: AV and VV delay optimized BV pacing acutely improve ICG CO and ACI and their NYHA class during long-term follow-up. ICG may be a simple and useful technique to optimize AV and VV delay in CRT.
Introduction: Cardiac resynchronization therapy (CRT) with left ventricular (LV) pacing is an established therapy for heart failure (HF) patients (P) with ventricular desynchronisation and reduced LV ejection fraction (EF). The aim of this study was to test the utilization of the transesophageal approach to measure arterial pulse pressure (PP) during LV pacing and electrical interventricular conduction delay (IVCD), to better select patients for CRT.
Methods: 32 HF patients (age 64 ± 10 years; 5 females, 27 males) with New York Heart Association (NYHA) class 2.8 ± 0.6, 27 ± 11 % LV EF and 155 ± 35 ms QRS duration were analysed with semi-invasive left cardiac pacing and electrocardiography. Esophageal TO8 Osypka catheter of 10.5 F diameter was perorally applied to the esophagus and placed in the position of maximum left atrial (LA) deflection and maximum LV deflection to measure PP with VAT or D00 pacing modes.
Results: Temporary transesophageal LV pacing was possible with VAT mode (n=16) and D00 mode (n=16) in all patients. In 15 Δ-PP-responders, PP was higher during LV pacing on than LV pacing off (78.3 ± 26.6 versus 65.9 ± 23.7 mmHg, P < 0.001) and NYHA class improved from 3.1 ± 0.35 to 2.1 ± 0.35 (P < 0.001) during 29 ± 26 month biventricular (BV) pacing follow-up (6 Medtronic and 9 Boston BV pacing devices). In 17 Δ-PP-non-responders, PP was not higher during LV pacing on than LV pacing off (61.5 ± 23.9 versus 60.9 ± 23.5 mmHg, P = 0.066). IVCD was significant longer in Δ-PP-responders than in Δ-PP-non-responders (87 ± 33 ms versus 37± 29 ms, P < 0.001).
Conclusion: Semi-invasive transesophageale LA and LV pacing with D00 and VAT mode and LV electrogram recording may be useful techniques to predict CRT improvement.
Background: Cardiac resynchronization therapy (CRT) is an established therapy for heart failure (HF) patients (P) with reduced left ventricular (LV) ejection fraction and electrical interventricular desynchronization, but not all P improved clinically. The aim of the study was to evaluate electrical interventricular delay (IVD) to LV delay (LVD) ratio in atrial fibrillation (AF) CRT responder (R) and non-responder (NR).
Methods: AF P (n = 18, age 60.6 ± 11.4 years, 1 female, 17 males) with HF New York Heart Association (NYHA) class 3.0 ± 0.2, 25.3 ± 5.9 % LV ejection fraction and 157.8 ± 24.4 ms QRS duration (QRSD) were measured by surface ECG and focused transesophageal bipolar LV ECG before implantation of CRT pacemaker (n = 2) or CRT defibrillator (n = 16). IVD was measured between onset of QRS in the surface ECG and onset of LV signal in the LV ECG. LVD was measured between onset and offset of LV signal in the LV ECG.
Results: Electrical ventricular desynchronization in AF CRT P were 61.9 ± 26.9ms IVD, 80.6 ± 24.3ms LVD, 0.85 ± 0.41 IVD-LVD-ratio (Figure), 3.12 ± 1.89 QRSD-IVD-ratio and 2.07 ± 0.47 QRSD-LVD-ratio. There were 72.2 % AF CRT R (n = 13) with 64.2 ± 24.6ms IVD and 77.8 ± 21.6ms LVD with Pearson correlation to 0.89 ± 0.39 IVD-LVD-ratio (r = 0.87, P < 0.01; r = -0.69, P < 0.01), 2.82 ± 1.32 QRSD-IVD-ratio (r = -0.76, P < 0.01; r = 0.67, P = 0.011) and 2.13 ± 0.46 QRSD-LVD-ratio (r = 0.57, P = 0.041; r = -0.85, P < 0.01). There were 27.8% AF CRT NR (n = 5) with 56.0 ± 34.5ms IVD and 87.8 ± 31.9ms LVD without correlation to 0.74 ± 0.48 IVD-LVD-ratio, 3.88 ± 2.98 QRSD-IVD-ratio and 1.90 ± 0.48 QRSD-LVD-ratio. During 15.3 ± 13.1 month CRT follow-up, the AF CRT R NYHA class improved from 3.0 ± 0.2 to 2.2 ± 0.3 (P < 0.001). During 18.8 ± 20.7 month CRT follow-up, the AF CRT NR NYHA class not improved from 3 to 3.3 ± 0.97.
Cardiac resynchronization therapy (CRT) is an established biventricular pacing therapy in heart failure patients with left bundle branch block and reduced left ventricular ejection fraction, but not all patients improved clinically as CRT responder. Purpose of the study was to evaluate electrical left atrial conduction delay (LACD) with focused transesophageal electrocardiography in CRT responder and CRT non-responder.
Methods: Twenty heart failure patients (age 66.6±8.2 years; 2 females, 18 males) with New York Heart Association functional class 3.0±0.3 and 174.2±40.2ms QRS duration were analysed using posterior left atrial transesophageal electrocardiography with hemispherical electrodes. Electrical LACD was measured between onset and offset of transesophageal left atrial signal before implantation of CRT devices.
Results: Electrical LACD could be evaluated by bipolar transesophageal left atrial electrocardiography using TO Osypka electrode in all heart failure patients with negative correlation between 54.7±18.1ms LACD and 24.9±6.4% left ventricular ejection fraction (r=-0.65, P=0.002). There were 16 CRT responders with reduction of New York Heart Association functional class from 3.0±0.29 to 2.1±0.2 (r=0.522, P=0.038) during 9.41±10.96 month biventricular pacing and negative correlation between 49.6±14.2ms LACD and 26.0±6.2% left ventricular ejection fraction (r=-0.533, P=0.034). There were 4 CRT non-responders with no reduction of New York Heart Association functional class from 3.0±0.4 to 2.8±0.5 (r=0.816, P=0.184) during with 13.88±16.39 month biventricular pacing and no correlation between 75.25±19.17ms LACD and 20.75±6.4% left ventricular ejection fraction (r=-0.831, P=0.169).
Conclusions: Focused transesophageal left atrial electrocardiography can be utilized to analyse electrical LACD in heart failure patients. LACD correlated negative with left ventricular ejection fraction in CRT responders. LACD may be a useful parameter to evaluate electrical left atrial desynchronization in heart failure patients.
Oesophageal Electrode Probe and Device for Cardiological Treatment and/or Diagnosis (EP3706626A1)
(2020)
The invention relates to an oesophageal electrode probe (10) for bioimpedance measurement and/or for neurostimulation; a device (100) for transoesophageal cardiological treatment and/or cardiological diagnosis; and a method for the open-loop or closed-loop control of a cardiac catheter ablation device and/or a cardiac, circulatory and/or respiratory support device. The oesophageal electrode probe comprises a bioimpedance measuring device for measuring the bioimpedance of at least one part of the tissue surrounding the oesophageal electrode probe. The bioimpedance device comprises at least one first and one second electrode, wherein the at least one first electrode (12A) is arranged on a side (14) of the oesophageal electrode probe facing towards the heart and the at least one second electrode (12B) is arranged on a side (16) of the oesophageal electrode probe facing away from the heart. The device (100) comprises the oesophageal electrode probe (10) and a control and/or evaluation device (30), which is configured for receiving a first bioimpedance measurement signal from the at least one first electrode (12A) and a second bioimpedance measurement signal from the at least one second electrode (12B), and comparing same, and generating a control signal on the basis of the comparison. The control signal can be a signal for the open-loop or closed-loop control of a cardiac catheter ablation device and/or a cardiac, circulatory and/or respiratory support device.
Targeting complex fractionated atrial electrocardiograms by automated algorithms during ablation of persistent atrial fibrillation has produced conflicting outcomes in previous electrophysiological studies and catheter ablation of atrial fibrillation and ventricular tachycardia. The aim of the investigation was to evaluate atrial and ventricular high frequency fractionated electrical signals with signal averaging technique.
Methods: Signal averaging electrocardigraphy allows high resolution ECG technique to eliminate interference noise signals in the recorded ECG. The algorithm use automatic ECG trigger function for signal averaged transthoracic, transesophageal and intra-cardiac ECG signals with novel LabVIEW software.
Results: The analysis in the time domain evaluated fractionated atrial signals at the end of the signal averaged P-wave and fractionated ventricular signals at the end of the QRS complex. We evaluated atrial flutter in the time domain with two-to-one atrioventricular conduction, 212.0 ± 4.1 ms atrial cycle length, 426.0 ± 8.2 ms ventricular cycle length, 58.2 ± 1.8 ms P-wave duration, 119.6 ± 6.4 ms PQ duration, 103.0 ± 2.4 ms QRS duration and 296.4 ± 6.8 ms QT duration. The analysis in the frequency domain evaluated high frequency fractionated atrial signals during the P-wave and high frequency fractionated ventricular signals during QRS complex.
Conclusions: Spectral analysis of signal averaging electrocardiography with novel LabVIEW software can be utilized to evaluate atrial and ventricular conduction delays in patients with atrial fibrillation and ventricular tachycardia. Complex fractionated atrial and ventricular electrocardiograms may be useful parameters to evaluate electrical cardiac bradycardia and tachycardia signals in atrial fibrillation and ventricular tachycardia ablation.
Solar irradiance prediction is vital for the power management and the cost reduction when integrating solar energy. The study is towards a ground image based solar irradiance prediction which is highly dependent on the cloud coverage. The sky images are collected by using ground based sky imager (fisheye lens). In this work, different algorithms for cloud detection being a preparation step for their segmentation are compared.
The need to measure basic aerosol parameters has increased dramatically in the last decade. This is due mainly to their harmful effect on the environment and on public health. Legislation requires that particle emissions and ambient levels, workplace particle concentrations and exposure to them are measured to confirm that the defined limits are met and the public is not exposed to harmful concentrations of aerosols.
The fisheye camera has been widely studied in the field of ground based sky imagery and robot vision since it can capture a wide view of the scene at one time. However, serious image distortion is a major drawback hindering its wider use. To remedy this, this paperproposes a lens calibration and distortion correction method for detecting clouds and forecasting solar radiation. Finally, the radial distortion of the fisheye image can be corrected by incorporating the estimated calibration parameters. Experimental results validate the effectiveness of the proposed method.
This paper deals with the detection and segmentation of clouds on high-dynamic-range (HDR) images of the sky as well as the calculation of the position of the sun at any time of the year. In order to predict the movement of clouds and the radiation of the sun for a short period of time, the clouds thickness and position have to be known as precisely as possible. Consequently, the segmentation algorithm has to provide satisfactory results regardless of different weather, illumination and climatic conditions. The principle of the segmentation is based on the classification of each pixel as a cloud or as a sky. This classification is usually based on threshold methods, since these are relatively fast to implement and show a low computational burden. In order to predict if and when the sun will be covered by clouds, the position of the sun on the images has to be determined. For this purpose, the zenith and azimuth angles of the sun are determined and converted into XY coordinates.
The characteristic features and applications of linear and nonlinear guided elastic waves propagating along surfaces (2D) and wedges (1D) are discussed. Laser-based excitation, detection, or contact-free analysis of these guided waves with pump–probe methods are reviewed. Determination of material parameters by broadband surface acoustic waves (SAWs) and other applications in nondestructive evaluation (NDE) are considered. The realization of nonlinear SAWs in the form of solitary waves and as shock waves, used for the determination of the fracture strength, is described. The unique properties of dispersion-free wedge waves (WWs) propagating along homogeneous wedges and of dispersive wedge waves observed in the presence of wedge modifications such as tip truncation or coatings are outlined. Theoretical and experimental results on nonlinear wedge waves in isotropic and anisotropic solids are presented.
Lithium–sulfur (Li/S) cells are promising candidates for a next generation of safe and cost-effective high energy density batteries for mobile and stationary applications. At present, most Li/S cells still suffer from relatively poor cyclability, capacity loss under moderate current densities and self-discharge. Furthermore, the underlying chemical mechanisms of the general discharge/charge behavior as well as Li/S-specific phenomena like the polysulfide shuttle are not yet fully understood. Here we present a thermodynamically consistent, fully reversible continuum model of a Li/S cell with simplified four-step electrochemistry, including a simple description of the polysulfide shuttle effect. The model is parameterized using experimental discharge curves obtained from literature and reproduces behavior at various current densities with fairly high accuracy. While being instructively simple, the presented model can still reproduce distinct macroscopic Li/S-cell features caused by the shuttle effect, e.g., seemingly infinite charging at low charge current densities, and suboptimal coulombic efficiency. The irreversible transport of active material from the cathode to the anode results in a voltage drop and capacity loss during cycling, which can also be observed experimentally.
Die Verwendung von Kameras als Messmittel für medizinische Anwendungen setzt deren präzise Kalibrierung voraus. Gängige Verfahren modellieren die Abbildungseigenschaften einer Kamera mittels perspektivischer Projektion und parametrisierter Funktionen zur Beschreibung von Linsenverzerrung. In den Randbereichen des Kamerabildes sind diese Modelle oft unzureichend. Außerdem bedingt die Verwendung starrer Kalibriermuster eine in der Regel kleine Anzahl an nicht gleichmäßig verteilten Punktkorrespondenzen zur Bestimmung der Modellparameter. In der vorliegenden Arbeit wird ein vollkommen neues und nicht auf Modellen basierendes Kalibrierverfahren vorgestellt, bei dem jedes Kamerapixel unabhängig von jedem anderen kalibriert wird.
In this paper we present a model of the discharge of a lithium–oxygen battery with aqueous electrolyte. Lithium–oxygen batteries (Li–O2) have recently received great attention due to their large theoretical specific energy. Advantages of the aqueous design include the stability of the electrolyte, the long experience with gas diffusion electrodes (GDEs), and the solubility of the reaction product lithium hydroxide. However, competitive specific energies can only be obtained if the product is allowed to precipitate. Here we present a dynamic one-dimensional model of a Li–O2 battery including a GDE and precipitation of lithium hydroxide. The model is parameterized using experimental data from the literature. We demonstrate that GDEs remove power limitations due to slow oxygen transport in solutions and that lithium hydroxide tends to precipitate on the anode side. We discuss the system architecture to engineer where nucleation and growth predominantly occurs and to optimize for discharge capacity.
Distribution of esophageal interventricular conduction delays in CRT patients and healthy subjects
(2015)
Semi-invasive electromechanical target interval to guide left ventricular electrode placement
(2011)
Electrical velocimetry to optimize VV delay in biventricular VVIR and DDD pacing for heart failure
(2011)
Introduction: VV delay (VVD) is the only parameter to hemodynamically optimize cardiac resynchronization therapy (CRT) for patients with atrial fibrillation (AF). Electrical velocimetry (EV) has been established to monitor thoracic electrical conductivity and to calculate hemodynamic surrogate parameters. We compared the response of this method to hemodynamic parameter changes between CRT patients with sinus rhythm (SR) and patients with AF.
Methods: VVD was individualized in 17 CRT patients in SR (12m, 5f, 67.0±7.2yrs.) after echo AV delay optimization and in 11 CRT patients in AF (10m, 1f, 69.8±9.6yrs.) using the Aesculon Cardiovascular Monitor (Osypka Medical, Berlin, Germany). Serial 30s EV recordings were accomplished, decreasing the VVD stepwise by 10ms from +60ms to -60ms between right and left ventricular stimulus. Optimal VVD was determined by the maximum of at least two of the three averaged parameters stroke volume (SV), cardiac output (CO) and cardiac index (CI). The response of SV, CO and CI was tested comparing their values in optimal VVD and suboptimal VVD. Suboptimal VVD was defined by optimal VVD±20ms.
Results: In all 28 patients in SR and AF, EV recordings resulted in optimal VVD. Between suboptimal and optimal mean VVD of 18.6±30.8ms between left and right ventricular stimulus, SV increased by 7.2±6.8%, CO by 7.8±7.2% and CI by 10.0±13.3% (all p<0.02). In the SR group with VVD of 18.8± 29.6ms, SV increased by 4.6±2.9%, CO by 5.0±2.9% and CI by 4.9±2.9% (all p<0.02). In the AF group with VVD of 18.2±4.0ms, SV increased by 10.4±8.9%, CO by 11.3±9.5% and CI by 16.4±18.2% (all p<0.02). Significant differences were not found between optimal VVD in SR and AF patients.
Conclusion: EV is a feasible serial method to individualize VVD in DDD and VVIR pacing for heart failure. Its response to hemodynamic changes demonstrates the value of EV for VVD fine-tuning.
Significance of new electrocardiographic parameters to improve cardiac resynchronization therapy
(2011)
Introduction: Oesophageal left heart electrogram (LHE) is a valuable tool providing electrocardiographic parameters for cardiac resynchronization therapy (CRT). It can be utilized to measure left ventricular (LVCD) and intra-leftventricular conduction delays (ILVCD) in heart failure patients to justify implantation of CRT systems. In the follow-up, LHE enables measurement of implant-related interatrial conduction times (IACT) which are the key intervals defining the hemodynamically optimal AV delay (AVD).
Methods: By TOSlim oesophageal electrode and Rostockfilter (Osypka AG, Rheinfelden, Germany), LHE was recorded in 39 heart failure patients (10f, 29m, 65±8yrs., QRS=163±21ms) after implantation of CRT systems according to guidelines. In position of maximal left ventricular deflection, LVCD and ILVCD were measured and compared with QRS width. In position of maximal left atrial deflection (LA), IACT was determined in VDD and DDD operation as interval As-LA and Ap-LA between atrial sense event (As) or stimulus (Ap), resp., and onset of LA. AVD was individualized using SAV =As-LA + 50ms for VDD and PAV=Ap-LA + 50ms for DDD operation.
Results: The CRT patients were characterized by minimal transoesophageal LVCD of 40ms but 73±20ms, at mean, ILVCD of 90±24ms and QRS/LVCD ratio of 2.4±0.6. The measured As-LA of 39±24ms and Ap-LA of 124±26ms resulted into SAV of 89±24ms and PAV of 174±26ms. In case of empirical AVD programming using 120ms for SAV and 180ms for PAV, the LHE revealed inverse sequences of LA and Vp in 4 patients (10%) during VDD and 13 patients (33%) in DDD pacing. In these patients, Vp preceded LA as IACT exceeded the programmed AVD.
Conclusion: Guideline indication of CRT systems is associated with LVCD of 40ms or more. Therefore, individual LVCD offers the minimal target interval that should be reached during left ventricular electrode placement to increase responder rate. Postoperatively, AV delay optimization respecting implant-related IACTs excludes adverse hemodynamic effects.
Using guideline parameters for indication of cardiac resynchronization therapy (CRT), only about two thirds of the patients improve clinically. Unfortunately both, surface ECG and echo are uncertain to predict CRT response. To better characterize cardiac desynchronization in heart failure, interventricular (IVCD) and intra-leftventricular conduction delays (ILVCD) were measured by esophageal left ventricular electrogram (LVE). Recordings in 43 CRT patients (34m, 9f, age: 64.7 ± 9.5yrs) evidenced only weak correlation between IVCD and QRS of 0.53 and between ILVCD and QRS of 0.33. This demonstrated that QRS duration is not a reliable indicator of desynchronization. Therefore, the study resulted into development of LVE feature for a programmer with implant support device. It can be used interoperatively to guide the left ventricular electrode location in order to increase responder rate in CRT.
AV delay (AVD) optimization can improve hemodynamics and avoid nonresponding to cardiac resynchronization therapy (CRT). AVD can be approximated by the sum of the individual implant-related interatrial conduction interval and a mean electromechanical interval of about 50ms. We searched for methods to facilitate automatic, implant-based AV delay optimization. In 25 patients (19m, 6f, age: 65±8yrs.) with Medtronic Insync III Marquis CRT-D series systems and left ventricular electrode at lateral or posterolateral wall, we determined interatrial conduction intervals by telemetric left ventricular tip versus superior vena cava coil electrogram (LVCE). Compared with esophageal measurements, the duration of optimal AV delay by LVCE showed good correlation (k=0.98, p=0.01) with a difference of 1.5±4.9ms, only. Therefore, LVCE is feasible to determine interatrial conduction intervals in order to automate AV delay optimization in CRT-D pacing promising increased accuracy compared to other algorithms.
Proton Exchange Membrane Fuel Cells (PEMFC) are energy efficient and environmentally friendly alternatives to conventional energy conversion systems in many yet emerging applications. In order to enable prediction of their performance and durability, it is crucial to gain a deeper understanding of the relevant operation phenomena, e.g., electrochemistry, transport phenomena, thermodynamics as well as the mechanisms leading to the degradation of cell components. Achieving the goal of providing predictive tools to model PEMFC performance, durability and degradation is a challenging task requiring the development of detailed and realistic models reaching from the atomic/molecular scale over the meso scale of structures and materials up to components, stack and system level. In addition an appropriate way of coupling the different scales is required.
This review provides a comprehensive overview of the state of the art in modeling of PEMFC, covering all relevant scales from atomistic up to system level as well as the coupling between these scales. Furthermore, it focuses on the modeling of PEMFC degradation mechanisms and on the coupling between performance and degradation models.