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Mice and rats make up 95% of all animals used in medical research and drug discovery and development. Monitoring of physiological functions such as ECG, blood pressure, and body temperature over the entire period of an experiment is often required. Restraining of the animals in order to obtain this data can cause great inconvenience. The use of telemetric systems solves this problem and provides more reliable results. However, these devices are mostly equipped with batteries, which limit the time of operation or they use passive power supplies, which affects the operating range. The semi-passive telemetric implant being presented is based on RFID technology and overcomes these obstacles. The device is inductively powered using the magnetic field of a common RFID reader device underneath the cage, but is also able to operate for several hours autonomously. Being independent from the battery capacity, it is possible to use the implant over a long period of time or to re-use the device several times in different animals, thus avoiding the disadvantages of existing systems and reducing the costs of purchase and refurbishment.
A new, small, and optimized for low power processor core named SIRIUS has been developed, simulated, synthesized to a netlist and verified. From this netlist, containing only primitives like gates and flip-flops, a mapping to an ASIC - or FPGA technology can easily be done with existing synthesizer tools, allowing very complex SOC designs with several blocks. Emulation via FPGA can be done on already simple setups and cheap hardware because of the small core size. The performance is estimated 50 MIPS on Cyclone II FPGA and about 100 MIPS on a 0.35 CMOS 5M2P technology with 4197 primitives used for the core, including a 16 x 16 multiplier. An example design of the ASIC for an electronic ePille device currently in development is shown.
A new approach of continuous phase QPSK Band-Pass modulation technique is being developed as enhancement to the QPSK modulation scheme for inductive data transmission (NFC). The modulation is based on Gaussian filtering of the phase transition from one state to the other rather than discontinuity in phase shift. The carrier is based on low frequency 115 KHz suitable for human body energy penetration due to its large skin-depth and lower inductive power attenuation. The complete signal processing is done digitally, external coil and capacitor is used for transceiver interface. The telemetry assists a smart pill swallowed by human being to trigger an actuator for drug delivery, record temperature, or perform diagnostic task inside the body. The smart pill includes 32bit processor, 16 Kbyte memory, temperature sensor, telemetry unit, and additional external peripheries. The complete system is designed, embedded in one SoC, and realized on ASIC with chip-area less than 14 mm<sup>2</sup>.