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Die drei großen Hersteller von Cochlea-Implantat (CI)-Systemen ermöglichen es klinischen Audiologen, die Mikrofoneigenschaften der meisten CI-Sprachprozessoren zu prüfen. Dazu können bei diesen Sprachprozessoren Monitorkopfhörer angeschlossen und das/die Mikrofon(e) inklusive eines Teils der Signalvorverarbeitung abgehört werden. Präzise Angaben dazu, mit welchen Stimuli, bei welchem Pegel und nach welchem Kriterium diese Prüfung stattfinden soll, machen die CI-Hersteller nicht. Auf Basis dieser Prüfung soll der Audiologe dann über die Funktion der Mikrofone und damit darüber entscheiden, ob der betreffende Sprachprozessor an den Hersteller eingeschickt wird oder nicht.
Zur Objektivierung der CI-Sprachprozessor-Mikrofon-Prüfung haben wir eine Testbox entwickelt, mit der alle abhörbaren aktuellen CI-Sprachprozessoren der drei großen Hersteller geprüft werden können. Die Box wurde im 3D-Druck-Verfahren hergestellt. Der zu prüfende Sprachprozessor wird in die Messbox eingehängt und über einen darin verbauten Lautsprecher mit definierten Prüfsignalen (Sinustöne unterschiedlicher Frequenz) beschallt. Das Mikrofonsignal wird über das Kabel der Monitorkopfhörer herausgeführt und mit einer Shifting- and Scaling-Schaltung in einen Spannungsbereich transformiert, der für die AD-Wandlung mit einem Mikrokontroller (ATmega1280 verbaut auf einem Arduino Mega) geeignet ist. Derselbe Mikrokontroller übernimmt über einen eigens gebauten DA-Wandler die Ausgabe der Sinustöne über den Lautsprecher. Signalaufnahme und –wiedergabe erfolgen mit jeweils 38,5 kHz Samplingrate. Der für jede Frequenz über mehrere Perioden des Prüfsignals ermittelte Effektivwert wird mit dem Effektivwert, der mit einem neuwertigen Referenzprozessor für diese Frequenz gemessen wurde, verglichen. Die Messergebnisse werden graphisch auf einem Display ausgegeben.
Derzeit läuft eine erste Datenerhebung mit in der Klinik subjektiv auffällig gewordenen CI-Sprachprozessoren, die anschließend in der Messbox untersucht werden. So sollen realistische Schwellen für kritische Abweichungen von den Referenz-Effektivwerten ermittelt werden. Im weiteren Verlauf sollen dann Hit und False Alarm-Raten der subjektiven Prüfung bestimmt werden.
The ability to detect a target signal masked by noise is improved in normal-hearing listeners when interaural phase differences (IPDs) between the ear signals exist either in the masker or in the signal. To improve binaural hearing in bilaterally implanted cochlear implant (BiCI) users, a coding strategy providing the best possible access to IPDs is highly desirable. Outcomes of a previous study (Zirn, Arndt et al. 2016) revealed that a subset of BiCI users showed improved IPD detection thresholds with the fine structure processing strategy FS4 compared to the constant rate strategy HDCIS using narrowband stimuli. In contrast, little differences between the coding strategies were found for broadband stimuli with regard to binaural speech intelligibility level differences (BILD) as an estimate of binaural unmasking. Compared to normalhearing listeners (7.5 ± 1.2 dB) BILD were small in BiCI users (around 0.5 dB with both coding strategies).
In the present work, we investigated the influence of binaural fitting parameters on BILD. In our cohort of BiCI users many were implanted with electrode arrays differing in length left versus right. Because this length difference typically corresponded to the distance of two electrode contacts the first modification of bilateral fitting was a tonotopic adjustment by deactivation of the most apical electrode contact on the side with the deeper inserted array (tonotopic approach).
The second modification was the isolation of the residual, most apical electrode contacts by deactivation of the basally adjacent electrode contact on each side (tonotopic sparse approach). Applying these modifications, BILD improved by up to 1.5 dB.
Das normalhörende auditorische System ist in der Lage, interaurale Zeit- bzw. Phasendifferenzen zur verbesserten Signaldetektion im Störgeräusch zu nutzen. Dieses Phänomen wird häufig als binaurale Entmaskierung bezeichnet und ist sowohl bei einfachen Signalen wie Sinustönen, als auch bei Sprachsignalen im Störgeräusch wirksam. Vorangegangene Studien haben gezeigt, dass binaurale Entmaskierung eingeschränkt auch bei bilateralen CI-Trägern beobachtbar ist (Zirn et al., 2016).
Aktuelle Ergebnisse zeigen, dass die binaurale Entmaskierung sensitiv gegenüber der bilateralen CI-Anpassung ist. So lässt sich der Effekt durch tonotopen Abgleich und Herausstellen eines apikalen Feinstrukturkanals modulieren. Steigerungen der binauralen Entmaskierung um bis zu 1,5 dB sind auf diese Weise gegenüber der konventionellen CI-Anpassung möglich. Allerdings variiert der Einfluss der CI-Anpassung interindividuell erheblich.
Spectral analysis of signal averaging electrocardiography in atrial and ventricular tachyarrhythmias
(2017)
Background: Targeting complex fractionated atrial electrograms detected by automated algorithms during ablation of persistent atrial fibrillation has produced conflicting outcomes in previous electrophysiological studies. The aim of the investigation was to evaluate atrial and ventricular high frequency fractionated electrical signals with signal averaging technique.
Methods: Signal averaging electrocardiography (ECG) allows high resolution ECG technique to eliminate interference noise signals in the recorded ECG. The algorithm uses automatic ECG trigger function for signal averaged transthoracic, transesophageal and intracardiac ECG signals with novel LabVIEW software (National Instruments, Austin, Texas, USA). For spectral analysis we used fast fourier transformation in combination with spectro-temporal mapping and wavelet transformation for evaluation of detailed information about the frequency and intensity of high frequency atrial and ventricular signals.
Results: Spectral-temporal mapping and wavelet transformation of the signal averaged ECG allowed the evaluation of high frequency fractionated atrial signals in patients with atrial fibrillation and high frequency ventricular signals in patients with ventricular tachycardia. The analysis in the time domain evaluated fractionated atrial signals at the end of the signal averaged P-wave and fractionated ventricular signals at the end of the QRS complex. The analysis in the frequency domain evaluated high frequency fractionated atrial signals during the P-wave and high frequency fractionated ventricular signals during QRS complex. The combination of analysis in the time and frequency domain allowed the evaluation of fractionated signals during atrial and ventricular conduction.
Conclusions: Spectral analysis of signal averaging electrocardiography with novel LabVIEW software can utilized to evaluate atrial and ventricular conduction delays in patients with atrial fibrillation and ventricular tachycardia. Complex fractionated atrial electrograms may be useful parameters to evaluate electrical cardiac arrhythmogenic signals in atrial fibrillation ablation.
eTPL: An Enhanced Version of the TLS Presentation Language Suitable for Automated Parser Generation
(2017)
The specification of the Transport Layer Security (TLS) protocol defines its own presentation language used for the purpose of semi-formally describing the structure and on-the-wire format of TLS protocol messages. This TLS Presentation Language (TPL) is more expressive and concise than natural language or tabular descriptions, but as a result of its limited objective has a number of deficiencies. We present eTPL, an enhanced version of TPL that improves its expressiveness, flexibility, and applicability to non-TLS scenarios. We first define a generic model that describes the parsing of binary data. Based on this, we propose language constructs for TPL that capture important information which would otherwise have to be picked manually from informal protocol descriptions. Finally, we briefly introduce our software tool etpl-tool which reads eTPL definitions and automatically generates corresponding message parsers in C++. We see our work as a contribution supporting sniffing, debugging, and rapid-prototyping of wired and wireless communication systems.
The low cost and small size of MEMS inertial sensors allows their combination into a multi sensor module in order to improve performance. However the different linear accelerations measured on different places on a rotating rigid body have to be considered for the proper fusion of the measurements. The errors in measurement of MEMS inertial sensors include deterministic imperfection, but also random noise. The gain in accuracy of using multiple sensors depends strongly on the correlation between these errors from the different sensors. Although for sensor fusion it usually assumed that the measurement errors of different sensors are uncorrelated, estimation theory shows that for the combination of the same type of sensors actually a negative correlation will be more beneficial. Therefore we describe some important and often neglected considerations for the combination of several sensors and also present some preliminary results with regard to the correlation of measurements from a simple multi sensor setup.
The Thread protocol is a recent development based on 6LoWPAN (IPv6 over IEEE 802.15.4), but with extensions regarding a more media independent approach, which – additionally – also promises true interoperability. To evaluate and analyse the operation of a Thread network a given open source 6LoWPAN stack for embedded devices (emb::6) has been extended in order to comply with the Thread specification. The implementation covers Mesh Link Establishment (MLE) and network layer functionality as well as 6LoWPAN mesh under routing mechanism based on MAC short addresses. The development has been verified on a virtualization platform and allows dynamical establishment of network topologies based on Thread's partitioning algorithm.
A novel approach of a test environment for embedded networking nodes has been conceptualized and implemented. Its basis is the use of virtual nodes in a PC environment, where each node executes the original embedded code. Different nodes run in parallel, connected via so-called virtual channels. The environment allows to modifying the behavior of the virtual channels as well as the overall topology during runtime to virtualize real-life networking scenarios. The presented approach is very efficient and allows a simple description of test cases without the need of a network simulator. Furthermore, it speeds up the process of developing new features as well as it supports the identification of bugs in wireless communication stacks. In combination with powerful test execution systems, it is possible to create a continuous development and integration flow.
A novel approach of a testbed for embedded networking nodes has been conceptualized and implemented. It is based on the use of virtual nodes in a PC environment, where each node executes the original embedded code. Different nodes are running in parallel and are connected via so-called virtual interfaces. The presented approach is very efficient and allows a simple description of test cases without the need of a network simulator. Furthermore, it speeds up the process of developing new features.
OPC UA (Open Platform Communications Unified Architecture) is already a well-known concept used widely in the automation industry. In the area of factory automation, OPC UA models the underlying field devices such as sensors and actuators in an OPC UA server to allow connecting OPC UA clients to access device-specific information via a standardized information model. One of the requirements of the OPC UA server to represent field device data using its information model is to have advanced knowledge about the properties of the field devices in the form of device descriptions. The international standard IEC 61804 specifies EDDL (Electronic Device Description Language) as a generic language for describing the properties of field devices. In this paper, the authors describe a possibility to dynamically map and integrate field device descriptions based on EDDL into OPCUA.
The paper describes the hardware and software architecture of the developed multi MEMS sensor prototype module, consisting of ARM Cortex M4 STM32F446 microcontroller unit, five 9-axis inertial measurement units MPU9255 (3D accelerometer, 3D gyroscope, 3D magnetometer and temperature sensor) and a BMP280 barometer. The module is also equipped with WiFi wireless interface (Espressif ESP8266 chip). The module is constructed in the form of a truncated pyramid. Inertial sensors are mounted on a special basement at different angles to each other to eliminate hardware sensors drifts and to provide the capability for self-calibration. The module fuses information obtained from all types of inertial sensors (acceleration, rotation rate, magnetic field and air pressure) in order to calculate orientation and trajectory. It might be used as an Inertial Measurement Unit, Vertical Reference Unit or Attitude and Heading Reference System.
Legacy industrial communication protocols are proved robust and functional. During the last decades, the industry has invented completely new or advanced versions of the legacy communication solutions. However, even with the high adoption rate of these new solutions, still the majority industry applications run on legacy, mostly fieldbus related technologies. Profibus is one of those technologies that still keep on growing in the market, albeit a slow in market growth in recent years. A retrofit technology that would enable these technologies to connect to the Internet of Things, utilize the ever growing potential of data analysis, predictive maintenance or cloud-based application, while at the same time not changing a running system is fundamental.
Climate change and resultant scarcity of water are becoming major challenges for countries around the world. With the advent of Wireless Sensor Networks (WSN) in the last decade and a relatively new concept of Internet of Things (IoT), embedded systems developers are now working on designing control and automation systems that are lower in cost and more sustainable than the existing telemetry systems for monitoring. The Indus river basin in Pakistan has one of the world's largest irrigation systems and it is extremely challenging to design a low-cost embedded system for monitoring and control of waterways that can last for decades. In this paper, we present a hardware design and performance evaluation of a smart water metering solution that is IEEE 802.15.4-compliant. The results show that our hardware design is as powerful as the reference design, but allows for additional flexibility both in hardware and in firmware. The indigenously designed solution has a power added efficiency (PAE) of 24.7% that is expected to last for 351 and 814 days for nodes with and without a power amplifier (PA). Similarly, the results show that a broadband communication (434 MHz) over more than 3km can be supported, which is an important stepping stone for designing a complete coverage solution of large-scale waterways.
Due to climate change and scarcity of water reservoirs, monitoring and control of irrigation systems is now becoming a major focal area for researchers in Cyber-Physical Systems (CPS). Wireless Sensor Networks (WSNs) are rapidly finding their way in the field of irrigation and play the key role as data gathering technology in the domain of IoT and CPS. They are efficient for reliable monitoring, giving farmers an edge to take precautionary measures. However, designing an energy-efficient WSN system requires a cross-layer effort and energy-aware routing protocols play a vital role in the overall energy optimization of a WSN. In this paper, we propose a new hierarchical routing protocol suitable for large area environmental monitoring such as large-scale irrigation network existing in the Punjab province of Pakistan. The proposed protocol resolves the issues faced by traditional multi-hop routing protocols such as LEACH, M-LEACH and I-LEACH, and enhances the lifespan of each WSN node that results in an increased lifespan of the whole network. We used the open-source NS3 simulator for simulation purposes and results indicate that our proposed modifications result in an average 27.8% increase in lifespan of the overall WSN when compared to the existing protocols.
With increasing flexible AC transmission system (FACTS) devices in operation, like the most versatile unified power flow controller (UPFC), the AC/DC transmission flexibility and power system stability have been suffering unprecedented challenge. This paper introduces the user-defined modeling (UDM) method into the UPFC dynamic modeling process, to deal with the challenging requirements of power system operation. This has also been verified using a leading-edge stability analysis software named DSATools TM in the IEEE-39 bus benchmark system. The characteristics of steady-state and dynamic responses are compared and analyzed under different conditions. Furthermore, simulation results prove the feasibility and effectiveness of the proposed UPFC in terms of both the independent regulation of power flow and the improvement of transient stability.
Heart rhythm model and simulation of electrophysiological studies and high-frequency ablations
(2017)
Background: Target of the study was to create an accurate anatomic CAD heart rhythm model, and to show its usefulness for cardiac electrophysiological studies and high-frequency ablations. The method is more careful for the patients’ health and has the potential to replace clinical studies due to its high efficiency regarding time and costs.
Methods: All natural heart components of the new HRM were based on MRI records, which guaranteed electronic functionality. The software CST was used for the construction, while CST’s material library assured genuine tissue properties. It should be applicable to simulate different heart rhythm diseases as well as various diffusions of electromagnetic fields, caused by electrophysiological conduction, inside the heart tissue.
Results: It was achievable to simulate sinus rhythm and fourteen different heart rhythm disturbance with different atrial and ventricular conduction delays. The simulated biological excitation of healthy and sick HRM were plotted by simulated electrodes of four polar right atrial catheter, six polar His bundle catheter, ten polar coronary sinus catheter, four polar ablation catheter and eight polar transesophageal left cardiac catheter. Accordingly, six variables were rebuilt and inserted into the anatomic HRM in order to establish heart catheters for ECG monitoring and HF ablation. The HF ablation catheters made it possible to simulate various types of heart rhythm disturbance ablations with different HF ablation catheters and also showed a functional visualisation of tissue heating. The use of tetrahedral meshing HRM made it attainable to store the results faster accompanied by a higher degree of space saving. The smart meshing function reduced unnecessary high resolutions for coarse structures.
Conclusions: The new HRM for EPS simulation may be additional useful for simulation of heart rhythm disturbance, cardiac pacing, HF ablation and for locating and identification of complex fractioned signals within the atrium during atrial fibrillation HF ablation.
Heart rhythm model and simulation of electrophysiological studies and high-frequency ablations
(2017)
Background: The simulation of complex cardiologic structures has the potential to replace clinical studies due to its high efficiency regarding time and costs. Furthermore, the method is more careful for the patients’ health than the conventional ways. The aim of the study was to create an anatomic CAD heart rhythm model (HRM) as accurate as possible, and to show its usefulness for cardiac electrophysiological studies (EPS) and high-frequency (HF) ablations.
Methods: All natural heart components of the new HRM were based on MRI records, which guaranteed electronic functionality. The software CST (Computer Simulation Technology, Darmstadt) was used for the construction, while CST’s material library assured genuine tissue properties. It should be applicable to simulate different heart rhythm diseases as well as various diffusions of electromagnetic fields, caused by electrophysiological conduction, inside the heart tissue.
Results: It was achievable to simulate normal sinus rhythm and fourteen different heart rhythm disturbance with different atrial and ventricular conduction delays. The simulated biological excitation of healthy and sick HRM were plotted by simulated electrodes of four polar right atrial catheter, six polar His bundle catheter, ten polar coronary sinus catheter, four polar ablation catheter and eight polar transesophageal left cardiac catheter (Fig.). Accordingly, six variables were rebuilt and inserted into the anatomic HRM in order to establish heart catheters for ECG monitoring and HF ablation. The HF ablation catheters made it possible to simulate various types of heart rhythm disturbance ablations with different HF ablation catheters and also showed a functional visualisation of tissue heating. The use of tetrahedral meshing HRM made it attainable to store the results faster accompanied by a higher degree of space saving. The smart meshing function reduced unnecessary high resolutions for coarse structures.
Conclusions: The new HRM for EPS simulation may be additional useful for simulation of heart rhythm disturbance, cardiac pacing, HF ablation and for locating and identification of complex fractioned signals within the atrium during atrial fibrillation HF ablation.