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The idea of this game is to use a flashcard system to create a short story in a foreign language. The story is developed by a group of people by exchanging sentences via a flashcard system. This way, people can learn from each other without fear of making mistakes because the group members are anonymous.
A platform of an electronic capsule is being developed for multi-task medical assistant application. It includes a near field telemetry unit for bidirectional communication system of 115 KHz low carrier frequency for inductive data transmission suited for human body energy transfer. The system triggers an actuator for drug delivery in various time and release forms via wireless external control, it has the ability to record temperature, measure pH of the body (additional sensors), and retrieve data to the outside. It consists of a 32bit processor, memory, external peripheries, and detection facility. The complete system is designed to fit small-size mass medical application with low power consumption, size of 7x25mm. The system is designed, simulated and emulated on FPGA. A final layout of the complete chip design is still under progress.
Transcatheter aortiv valve implantation is a new safe strategy treatment for patients with symptomatic severe aortic stenosis and high operative risk. The aim of the study was to compare the pre-and post- muiscatheter aortiv valve implantation procedures to determine the atrioventricuktr conduction time as a potential predictor of permanent pacemaker therapy requirement after transcatheter aortiv valve implantation. The transcatheter aortiv valve implantation patients were divided into groups without pacemaker and with dual or single chamber pacemEtker with diffent atrioventrieular conduction time disturbance before and after transcatheter aortiv valve implantation. In heart failure, patients without permanent pacemaker therapy after transcatheter aortiv valve implantation, atrioventricular conduction time was prolonged after transcatheter aortiv valve implantation. In patients with permanent dual chamber pacemaker therapy after transcatheter aortiv valve implantation, atrioventricular conduction time was normalised with dual chaniber atrioventrieuku pacing mode. Atrioventricular conduction time may be a useful parameter to evaluate the risk of post-procedural atrioventricular conduction block and permanent pacemaker therapy in transcatheter north, valve implantation patients.
Do you know that for each banana bunch the complete plant must be cut as well? Only in Brazil 440 million trees are planted annually. With an average weight of 30 kg per banana plant you can estimate about 13,5 million tons of banana residues per year. Although there exist some projects to use these residues for the production of valuable products (e.g fibers for textile and paper production) most of this organic waste material is unused and left for composting on the farmland.
The basic idea of this project is to evaluate this organic waste material for converting it to a renewable and CO2 neutral fuel. Therefore, the different parts of the banana plant (heart, leaves and pseudo stem) were analyzed regarding their biogas potential (specific biogas yield and biogas production kinetics). In further studies the effect of mechanical and enzymatic pretreatments of the different parts of the plants was investigated. This examination could then be the basis for an energetic usage of this organic residue.
The biogas batch experiments were performed according to the german guideline VDI 4630 in 2-L-Batch reactors at 37°C. As biogas substrates, the heart, the leaves and the pseudo stem of the banana plant residue with and without enzymatic/mechanical pretreatment were used.
The different parts of the banana plants result in a specific biogas production yield in the range of 260-470 norm liters per kg organic dry mass.
To determine the influence of the mechanical pretreatment (particle size 1-15 mm) on the biogas production kinetics, the kinetic constants were defined and calculated. The reduction of the particle size leads to an improved biogas production kinetics. Therefore experiments will demonstrate, if the results from the batch experiments can be converted in the continuous fed biogas reactor. The experiments of the enzymatic pretreatment are still under investigation.
Flashcards are a well known and proven method to learn and memorise. Such a way of learning is perfectly suited for “learning on the way,” but carrying all the flashcards could be awkward. In this scenario, a mobile device (mobile phone) is an adequate solution. The new mobile device operating system Android from Google allows for writing multimedia-enriched applications.
Die angestrebten Klimaschutzziele erfordern, dass Erneuerbare Energien längerfristig zur Hauptenergiequelle der Energieversorgung werden. Um dieses ehrgeizige Ziel zu erreichen, ist es angebracht konventionelle und erneuerbare Energie oder noch besser nachhaltige Einzelprozesse intelligent miteinander zu verknüpfen.
Das Projekt EBIPREP wird von einer interdisziplinären Forschergruppe bestehend aus Chemikern, Prozessingenieuren und Bioprozessingenieuren sowie Physikern, die auf Sensoren und Prozesssteuerung spezialisiert sind durchgeführt. Das Ziel ist es, neue Lösungen für die Nutzungswege von Holzhackschnitzeln und den bei der mechanischen Trocknung anfallenden Holzpresssaft zu entwickeln. Neben der Hackschnitzelvergasung und der katalytischen Reinigung des Holzgases steht die Nutzung des Holzpresssafts in Biogasanlagen und bei der biotechnologischen Wertstofferzeugung, z.B. bei der Enzymherstellung, im Vordergrund.
Was wir tun?
Das EBIPREP-Projekt wird von einer interdisziplinären Forschungsgruppe durchgeführt, die sich aus Chemikern, Prozessingenieuren, Bioprozessingenieuren und Physikern zusammensetzt. Ziel ist es, neue Lösungen für den Einsatz von Hackschnitzeln und Holzpresssaft zu entwickeln, die durch ein innovatives mechanisches Trocknungsverfahren gewonnen werden. Neben der Holzvergasung und katalytischen Reinigung des Holzgases ist der Einsatz von Holzpresssaft in Biogasanlagen und in biotechnologischen Produktionsprozessen von Wertstoffen vorgesehen. Holzhackschnitzel werden thermisch vergast. Es werden Online-Sensoren entwickelt, um die relevanten Parameter der stabilisierten und optimierten Einzelprozesse auszuwerten. Die Verknüpfung von thermischen und biotechnologischer Konversionsprozessen könnte dazu beitragen, die Dimension von Biogasreaktoren erheblich zu reduzieren. Diese Tatsache wird folglich zu einer spürbaren Kostensenkung führen.
Ziele des EBIPREP-Projekts
• die Vorteile der thermischen und biologischen Umwandlung von Biomasse zu kombinieren;
• Entwicklung eines Verfahrens zur Reduzierung von Schadstoffemissionen mit innovativen Sensoren und katalytische Behandlung von Synthesegasen;
• nachhaltige Produktion biotechnologischer wertvoller Produkte
• wirtschaftliche und ökologische Analyse des Gesamtprozesses im Vergleich zu den Einzelprozessen
• Einsatz von Prozessabwässern zur Erzeugung regenerativer Energie oder biotechnologischer Wertstoffe
• Erwerb neuer Kenntnisse auf dem Gebiet der Rückgewinnungstechnik von Rückständen
• und Energieerzeugung;
• Erweiterung neuer Anwendungsfelder für innovative Sensoren und Keramik
• Schäume für Katalysatoren;
• Senkung der Kosten für die Biogasproduktion
Im geplanten Übersichtsvortrag werden die vernetzten Strukturen des Projekts EBIPREP und deren zentralen Ergebnisse vorgestellt.
Micronization of biochar (BC) may ease its application in agriculture. For example, fine biochar powders can be applied as suspensions via drip-irrigation systems or can be used to produce grnulated fertilizers. However, micronization may effect important physical biochar properties like the water holding capacity (WHC) or the porosity.
Background: A disturbed synchronization of the ventricular contraction can cause a highly developed systolic heart failure in affected patients, which can often be explained by a diseased left bundle branch block (LBBB). If medication remains unresponsive, the concerned patients will be treated with a cardiac resynchronization therapy (CRT) system. The aim of this study was to integrate His bundle pacing into the Offenburg heart rhythm model in order to visualize the electrical pacing field generated by His bundle pacing.
Methods: Modelling and electrical field simulation activities were performed with the software CST (Computer Simulation Technology) from Dessault Systèms. CRT with biventricular pacing is to be achieved by an apical right ventricular electrode and an additional left ventricular electrode, which is floated into the coronary vein sinus. This conventional type of biventricular pacing leads to a reduction of the left ventricular ejection fraction. Furthermore, the non-responder rate of the CRT therapy is about one third of the CRT patients.
Results: His bundle pacing represents a physiological alternative to conventional cardiac pacing and cardiac resynchronization. An electrode implanted in the His bundle emits a stronger electrical pacing field than the electrical pacing field of conventional cardiac pacemakers. The pacing of the His bundle was performed by the Medtronic Select Secure 3830 electrode with pacing voltage amplitudes of 3 V, 2 V and 1.5 V in combination with a pacing pulse duration of 1 ms.
Conclusions: Compared to conventional cardiac pacemaker pacing, His bundle pacing is capable of bridging LBBB conduction disorders in the left ventricle. The His bundle pacing electrical field is able to spread via the physiological pathway in the right and left ventricles for CRT with a narrow QRS-complex in the surface ECG.
Heart rhythm model and simulation of electrophysiological studies and high-frequency ablations
(2017)
Background: Target of the study was to create an accurate anatomic CAD heart rhythm model, and to show its usefulness for cardiac electrophysiological studies and high-frequency ablations. The method is more careful for the patients’ health and has the potential to replace clinical studies due to its high efficiency regarding time and costs.
Methods: All natural heart components of the new HRM were based on MRI records, which guaranteed electronic functionality. The software CST was used for the construction, while CST’s material library assured genuine tissue properties. It should be applicable to simulate different heart rhythm diseases as well as various diffusions of electromagnetic fields, caused by electrophysiological conduction, inside the heart tissue.
Results: It was achievable to simulate sinus rhythm and fourteen different heart rhythm disturbance with different atrial and ventricular conduction delays. The simulated biological excitation of healthy and sick HRM were plotted by simulated electrodes of four polar right atrial catheter, six polar His bundle catheter, ten polar coronary sinus catheter, four polar ablation catheter and eight polar transesophageal left cardiac catheter. Accordingly, six variables were rebuilt and inserted into the anatomic HRM in order to establish heart catheters for ECG monitoring and HF ablation. The HF ablation catheters made it possible to simulate various types of heart rhythm disturbance ablations with different HF ablation catheters and also showed a functional visualisation of tissue heating. The use of tetrahedral meshing HRM made it attainable to store the results faster accompanied by a higher degree of space saving. The smart meshing function reduced unnecessary high resolutions for coarse structures.
Conclusions: The new HRM for EPS simulation may be additional useful for simulation of heart rhythm disturbance, cardiac pacing, HF ablation and for locating and identification of complex fractioned signals within the atrium during atrial fibrillation HF ablation.
The ability to detect a target signal masked by noise is improved in normal-hearing listeners when interaural phase differences (IPDs) between the ear signals exist either in the masker or in the signal. To improve binaural hearing in bilaterally implanted cochlear implant (BiCI) users, a coding strategy providing the best possible access to IPDs is highly desirable. Outcomes of a previous study (Zirn, Arndt et al. 2016) revealed that a subset of BiCI users showed improved IPD detection thresholds with the fine structure processing strategy FS4 compared to the constant rate strategy HDCIS using narrowband stimuli. In contrast, little differences between the coding strategies were found for broadband stimuli with regard to binaural speech intelligibility level differences (BILD) as an estimate of binaural unmasking. Compared to normalhearing listeners (7.5 ± 1.2 dB) BILD were small in BiCI users (around 0.5 dB with both coding strategies).
In the present work, we investigated the influence of binaural fitting parameters on BILD. In our cohort of BiCI users many were implanted with electrode arrays differing in length left versus right. Because this length difference typically corresponded to the distance of two electrode contacts the first modification of bilateral fitting was a tonotopic adjustment by deactivation of the most apical electrode contact on the side with the deeper inserted array (tonotopic approach).
The second modification was the isolation of the residual, most apical electrode contacts by deactivation of the basally adjacent electrode contact on each side (tonotopic sparse approach). Applying these modifications, BILD improved by up to 1.5 dB.