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Taschenbuch Digitaltechnik
(2014)
Geschichte(n) der Medizin
(2014)
Seit Menschengedenken schreibt die Medizin ihre eigene(n) Geschichte(n). Bis heute faszinieren Berichte über Krankheiten oder Todesfolgen vergangener Zivilisationen, Herrscher und Persönlichkeiten. In diesem Band werden ausgewählte Vitae aus der Zeit zwischen dem zweiten Jahrhundert vor Christus und heute exemplarisch und kurzweilig vorgestellt.
Doch nicht nur die hier wiedergegebenen Krankheitsverläufe der prominenten Protagonisten faszinieren. Mindestens genauso bemerkenswert sind die dargestellten Veränderungen von Moral-Vorstellungen innerhalb der Geschichte(n): So verbietet beispielsweise der Eid des Hippokrates das Blasenstein¬-Schneiden – doch heute ist die Entfernung von Nephrolithen immanenter Bestandteil der Urologie. Und während die Deklaration des Weltärztebundes aus dem Jahr 1948 – das sogenannte Genfer Gelöbnis – den Schwangerschaftsabbruch noch ablehnt, ist dieser heutzutage (in engen Grenzen) erlaubt.
Den renommierten Autoren des vorliegenden Bandes gelingt es mühelos und mitreißend, Geschichte(n) der Medizin in Biografien und Erzählungen lebendig werden zu lassen. Ihre historischen Betrachtungen sind gleichermaßen unterhaltsam wie lehrreich.
Geschichte(n) der Medizin
(2015)
Renommierte Autoren erzählen lebendige und mitreißende Geschichte(n) der Medizin über Krankheiten, Ärzte und Forscher.
-Wie kam es zur Entdeckung des Blutkreislaufes, wo man doch lange Zeit glaubte, die Leber produziere täglich Tausende von Litern Blut?
-Warum sind Hirnschrittmacher erst viel später als Herzschrittmacher auf der medizinischen Bühne erschienen, wo doch das Gehirn schon in der Antike trepaniert und erforscht wurde?
-Die Antworten auf diese und andere Fragen werden nicht nur wissenschaftlich exakt, sondern auch überaus unterhaltsam gegeben.
-Beachtlich, dass Friedrich II. von Preußen auch begnadeter Hobby-Arzt war.
-Bemerkenswert, wie eine Frau zu einer Zeit zielstrebig Ärztin wurde, als nur Männer Medizin studieren durften.
-Bewegend die Erlebnisse eines Arztes an der Front.
-Faszinierend, wie ein „Wunderdoktor“ reihenweise Frauen in Ohnmacht versetzte, um sie zu heilen; er wurde damit zum Mitbegründer der Psychotherapie.
-Das Buch knüpft mit diesen und weiteren Erzählungen an den großen Erfolg des ersten Bandes an und bietet in populärwissenschaftlicher Weise neues Lese- und Bildungsvergnügen.
Geschichte(n) der Medizin
(2016)
Nach dem großen Erfolg der beiden ersten Bände liegt jetzt der Abschluss der Trilogie vor. Renommierte Autorinnen und Autoren erzählen einmal mehr lebendige und mitreißende Geschichte(n) der Medizin über Krankheiten, Ärzte und Forscher. Wie kam es beispielsweise zur Entdeckung der "Perkussion"? Wer war Avicenna? Warum wurde der Name Goldberg so berühmt? Was haben Rembrandt und Schiller gemeinsam? Welchen Einfluss nahm deutsche Medizin auf den Fernen Osten? Die populärwissenschaftlich aufbereitete Welt der Medizingeschichte(n) fasziniert nicht nur, sie sorgt auch immer wieder für überraschende Erkenntnisse und Aha-Erlebnisse. Das Buch richtet sich daher gleichermaßen an medizinische Laien wie Fachleute.
PET and SPECT in Neurology
(2014)
PET and SPECT in Neurology highlights the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable to anybody in the field of neuroscience, from the neurologist and the radiologist/nuclear medicine specialist to the interested general practitioner and geriatrician. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.
PET and SPECT of Neurobiological Systems combines the expertise of renowned authors whose dedication to the development of novel probes and techniques for the investigation of neurobiological systems has achieved international recognition. Various aspects of neurotransmission in the brain are discussed, such as visualization and quantification of (more than 20 different) neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, β-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed.
Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to anyone in the field of clinical or preclinical neuroscience, from the radiochemist and radiologist/nuclear medicine specialist to the interested neurobiologist and general practitioner. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences. Other volumes focus on PET and SPECT in psychiatry and PET and SPECT in neurology".
PET and SPECT in Psychiatry
(2014)
PET and SPECT in Psychiatry showcases the combined expertise of renowned authors whose dedication to the investigation of psychiatric disease through nuclear medicine technology has achieved international recognition. The classical psychiatric disorders as well as other subjects – such as suicide, sleep, eating disorders, and autism – are discussed and the latest results in functional neuroimaging are detailed. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all who have an interest in the field of neuroscience, from the psychiatrist and the radiologist/nuclear medicine specialist to the interested general practitioner and cognitive psychologist. It is the first volume of a trilogy on PET and SPECT imaging in the neurosciences; other volumes will focus on PET and SPECT in neurology and PET and SPECT of neurobiological systems.
The excessive control signaling in Long Term Evolution networks required for dynamic scheduling impedes the deployment of ultra-reliable low latency applications. Semi-persistent scheduling was originally designed for constant bit-rate voice applications, however, very low control overhead makes it a potential latency reduction technique in Long Term Evolution. In this paper, we investigate resource scheduling in narrowband fourth generation Long Term Evolution networks through Network Simulator (NS3) simulations. The current release of NS3 does not include a semi-persistent scheduler for Long Term Evolution module. Therefore, we developed the semi-persistent scheduling feature in NS3 to evaluate and compare the performance in terms of uplink latency. We evaluate dynamic scheduling and semi-persistent scheduling in order to analyze the impact of resource scheduling methods on up-link latency.
Vehicle-to-Everything (V2X) communication promises improvements in road safety and efficiency by enabling low-latency and reliable communication services for vehicles. Besides using Mobile Broadband (MBB), there is a need to develop Ultra Reliable Low Latency Communications (URLLC) applications with cellular networks especially when safety-related driving applications are concerned. Future cellular networks are expected to support novel latencysensitive use cases. Many applications of V2X communication, like collaborative autonomous driving requires very low latency and high reliability in order to support real-time communication between vehicles and other network elements. In this paper, we classify V2X use-cases and their requirements in order to identify cellular network technologies able to support them. The bottleneck problem of the medium access in 4G Long Term Evolution(LTE) networks is random access procedure. It is evaluated through simulations to further detail the future limitations and requirements. Limitations and improvement possibilities for next generation of cellular networks are finally detailed. Moreover, the results presented in this paper provide the limits of different parameter sets with regard to the requirements of V2X-based applications. In doing this, a starting point to migrate to Narrowband IoT (NB-IoT) or 5G - solutions is given.
The next generation cellular networks are expected to improve reliability, energy efficiency, data rate, capacity and latency. Originally, Machine Type Communication (MTC) was designed for low-bandwidth high-latency applications such as, environmental sensing, smart dustbin, etc., but there is additional demand around applications with low latency requirements, like industrial automation, driver-less cars, and so on. Improvements are required in 4G Long Term Evolution (LTE) networks towards the development of next generation cellular networks for providing very low latency and high reliability. To this end, we present an in-depth analysis of parameters that contribute to the latency in 4G networks along with a description of latency reduction techniques. We implement and validate these latency reduction techniques in the open-source network simulator (NS3) for narrowband user equipment category Cat-Ml (LTE-M) to analyze the improvements. The results presented are a step towards enabling narrowband Ultra Reliable Low Latency Communication (URLLC) networks.
Integration of BACNET OPC UA-Devices Using a JAVA OPC UA SDK Server with BACNET Open Source Library
(2014)
In this paper we integrate the ideas of network coding and relays into an existing practical network architecture used in a wireless network scenario. Specifically, we use the COPE architecture to test our ideas. Since previous works have focused on the communication aspect at the physical layer level, we attempt to take it one step further by including the MAC layer. Our idea is based on information theoretic concepts developed by Shannon in order to reliably apply network coding to increase the net throughput.
The suffix-free-prefix-free hash function construction and its indifferentiability security analysis
(2012)
In this paper, we observe that in the seminal work on indifferentiability analysis of iterated hash functions by Coron et al. and in subsequent works, the initial value (IV) of hash functions is fixed. In addition, these indifferentiability results do not depend on the Merkle–Damgård (MD) strengthening in the padding functionality of the hash functions. We propose a generic n-bit-iterated hash function framework based on an n-bit compression function called suffix-free-prefix-free (SFPF) that works for arbitrary IVs and does not possess MD strengthening. We formally prove that SFPF is indifferentiable from a random oracle (RO) when the compression function is viewed as a fixed input-length random oracle (FIL-RO). We show that some hash function constructions proposed in the literature fit in the SFPF framework while others that do not fit in this framework are not indifferentiable from a RO. We also show that the SFPF hash function framework with the provision of MD strengthening generalizes any n-bit-iterated hash function based on an n-bit compression function and with an n-bit chaining value that is proven indifferentiable from a RO.
Um Simulationen schnell und kostengünstig sowie ergebnisträchtig durchzuführen, bedarf es einer sorgfältigen Vorbereitung. Der Artikel befaßt sich mit dem automatischen Ablauf einer Simulationstudie zum Materilafluß und erläutert die im Ablauf notwendigen Beiträge der Anwender. In den Einzelheiten wird über die automatische Vorgehensweise und Anwendung der Standard-Simulationsmodelle (SSM) sowie spezieller Simulationsmodule (SimDBC) berichtet. Entscheidend für eine breitere Anwendung von Simulationswerkzeugen ist die einfache Handhabung und leicht verständliche Definition der zu untersuchenden Szenarien.
Since their dawning, space communications have been among the strongest driving applications for the development of error correcting codes. Indeed, space-to-Earth telemetry (TM) links have extensively exploited advanced coding schemes, from convolutional codes to Reed-Solomon codes (also in concatenated form) and, more recently, from turbo codes to low-density parity-check (LDPC) codes. The efficiency of these schemes has been extensively proved in several papers and reports. The situation is a bit different for Earth-to-space telecommand (TC) links. Space TCs must reliably convey control information as well as software patches from Earth control centers to scientific payload instruments and engineering equipment onboard (O/B) spacecraft. The success of a mission may be compromised because of an error corrupting a TC message: a detected error causing no execution or, even worse, an undetected error causing a wrong execution. This imposes strict constraints on the maximum acceptable detected and undetected error rates.
The separation of nitrogen and methane from hydrogen-rich mixtures is systematically investigated on a recently developed binder-free zeolite 5A. For this adsorbent, the present work provides a series of experimental data on adsorption isotherms and breakthrough curves of nitrogen and methane, as well as their mixtures in hydrogen. Isotherms were measured at temperatures of 283–313 K and pressures of up to 1.0 MPa. Breakthrough curves of CH4, N2, and CH4/N2 in H2 were obtained at temperatures of 300–305 K and pressures ranging from 0.1 to 6.05 MPa with different feed concentrations. An LDF-based model was developed to predict breakthrough curves using measured and calculated data as inputs. The number of parameters and the use of correlations were restricted to focus on the importance of measured values. For the given assumptions, the results show that the model predictions agree satisfactorily with the experiments under the different operating conditions applied.
Im Rahmen einer Master Thesis wurde ausgehend von einem vorhandenen System On Chip Design, welches eingehende EKG-Datensignale verarbeitet, das bestehende System so erweitert dass es komplett über den standardisierten SPI-Bus steuerbar und auslesbar ist.
In den vergangenen Jahren ist das technische Gas Schwefelhexafluorid (SF6) immer wieder Gegenstand von Diskussionen des Klimaschutzes und der technischen Notwendigkeit für den Betrieb von Schaltanlagen gewesen und wird dies wohl auch noch für längere Zeit bleiben. Das Gas, welches sich aus einem Schwefelatom und sechs Fluoratomen zusammensetzt, wird seit Ende der sechziger 1960er Jahre in Schaltanlagen der Mittel- und Hochspannung eingesetzt. So günstig dessen Eigenschaften im technischen Einsatz auch sind, so klimaschädlich ist es beim Entweichen in die Atmosphäre. SF6 ist das Klimagas mit dem größten bekannten Treibhauspotenzial, es weist ein CO2-Äquivalent (GWP) von 23.900 und eine atmosphärische Lebensdauer von ca. 3.200 Jahren auf. Neben nur wenig verbliebenen Anwendungen in Industrie, Militär und Medizin kommt es heute hauptsächlich bei der elektrischen Energieversorgung als Isolier- und Lichtbogenlöschgas in Schaltanlagen von Übertragungs- und Verteilnetzen zum Einsatz. Grund genug die technische Notwendigkeit, mögliche Alternativen und Konsequenzen drohender Verbote zu diskutieren. In diesem Artikel werden zunächst die Grundlagen moderner SF6- Hochspannungsschaltanlagen vorgestellt, die Klimabelastung durch entweichendes SF6 evaluiert, ein Überblick über den Stand der Forschung gegeben und mögliche Konsequenzen eines Verbotes von Schwefelhexafluorid in der Energieversorgung diskutiert.
Background: Increasing awareness of the importance of evidence-based medicine is demonstrated not only by an increasing number of articles addressing it but also by a specialty-wide evidence-based medicine initiative. The authors critically analyzed the quality of reporting of randomized controlled trials published in this Journal over a 21-year period (1990 to 2010).
Methods: A hand search was conducted, including all issues of Plastic and Reconstructive Surgery from January of 1990 to December of 2010. All randomized controlled trials published during this time period were identified with the Cochrane decision tree for identification of randomized controlled trials. To assess the quality of reporting, a modification of the checklist of the Consolidated Standard of Reporting Trials Statement was used.
Results: Of 7121 original articles published from 1990 to 2010 in the Journal, 159 (2.23 percent) met the Cochrane criteria. A significant increase in the absolute number of randomized controlled trials was seen over the study period (p < 0.0001). The median quality of these trials from 1990 to 2010 was "fair," with a trend toward improved quality of reporting over time (p = 0.127).
Conclusions: A favorable trend is seen with respect to an increased number of published randomized controlled trials in Plastic and Reconstructive Surgery. Adherence to standard reporting guidelines is recommended, however, to further improve the quality of reporting. Consideration may be given to providing information regarding the quality of reporting in addition to the "level of evidence pyramid," thus facilitating critical appraisal.
Structured Innovation with TRIZ in Science and Industry - Creating Value for Customers and Society
(2016)
The design of control systems of concentrator photovoltaic power plants will be more challenging in the future. Reasons are cost pressure, the increasing size of power plants, and new applications for operation, monitoring and maintenance required by grid operators, manufacturers and plant operators. Concepts and products for fixed-mounted photovoltaic can only partly be adapted since control systems for concentrator photovoltaic are considerable more complex due to the required high accurate sun-tracking. In order to assure reliable operation during a lifetime of more than 20 years, robustness of the control system is one crucial design criteria. This work considers common engineering technics for robustness, safety and security. Potential failures of the control system are identified and their effects are analyzed. Different attack scenarios are investigated. Outcomes are design criteria that encounter both: failures of system components and malicious attacks on the control system of future concentrator photovoltaic power plants. Such design criteria are a transparent state management through all system layers, self-tests and update capabilities for security concerns. The findings enable future research to develop a more robust and secure control system for concentrator photovoltaics when implementing new functionalities in the next generation.
The communication system of a large-scale concentrator photovoltaic power plant is very challenging. Manufacturers are building power plants having thousands of sun tracking systems equipped with communication and distributed over a wide area. Research is necessary to build a scalable communication system enabling modern control strategies. This poster abstract describes the ongoing work on the development of a simulation model of such power plants in OMNeT++. The model uses the INET Framework to build a communication network based on Ethernet. First results and problems of timing and data transmission experiments are outlined. The model enables research on new communication and control approaches to improve functionality and efficiency of power plants based on concentrator photovoltaic technology.
In this paper an RFID/NFC (ISO 15693 standard) based inductively powered passive SoC (system on chip) for biomedical applications is presented. A brief overview of the system design, layout techniques and verification method is dis-cussed here. The SoC includes an integrated 32 bit microcontroller, sensor interface circuit, analog to digital converter, integrated RAM, ROM and some other peripherals required for the complete passive operation. The entire chip is realized in CMOS 0.18 μm technology with a chip area of 1.52mm x 3.24 mm.
An Ultra-Low-Power RFID/NFC Frontend IC Using 0.18 μm CMOS Technology for Passive Tag Applications
(2018)
Battery-less passive sensor tags based on RFID or NFC technology have achieved much popularity in recent times. Passive tags are widely used for various applications like inventory control or in biotelemetry. In this paper, we present a new RFID/NFC frontend IC (integrated circuit) for 13.56 MHz passive tag applications. The design of the frontend IC is compatible with the standard ISO 15693/NFC 5. The paper discusses the analog design part in details with a brief overview of the digital interface and some of the critical measured parameters. A novel approach is adopted for the demodulator design, to demodulate the 10% ASK (amplitude shift keying) signal. The demodulator circuit consists of a comparator designed with a preset offset voltage. The comparator circuit design is discussed in detail. The power consumption of the bandgap reference circuit is used as the load for the envelope detection of the ASK modulated signal. The sub-threshold operation and low-supply-voltage are used extensively in the analog design—to keep the power consumption low. The IC was fabricated using 0.18 μm CMOS technology in a die area of 1.5 mm × 1.5 mm and an effective area of 0.7 mm2. The minimum supply voltage desired is 1.2 V, for which the total power consumption is 107 μW. The analog part of the design consumes only 36 μW, which is low in comparison to other contemporary passive tags ICs. Eventually, a passive tag is developed using the frontend IC, a microcontroller, a temperature and a pressure sensor. A smart NFC device is used to readout the sensor data from the tag employing an Android-based application software. The measurement results demonstrate the full passive operational capability. The IC is suitable for low-power and low-cost industrial or biomedical battery-less sensor applications. A figure-of-merit (FOM) is proposed in this paper which is taken as a reference for comparison with other related state-of-the-art researches.
Design of a Programmable Passive SoC for Biomedical Applications Using RFID ISO 15693/NFC5 Interface
(2018)
Low power, low cost inductively powered passive biotelemetry system involving fully customized RFID/NFC interface base SoC has gained popularity in the last decades. However, most of the SoCs developed are application specific and lacks either on-chip computational or sensor readout capability. In this paper, we present design details of a programmable passive SoC in compliance with ISO 15693/NFC5 standard for biomedical applications. The integrated system consists of a 32-bit microcontroller, a sensor readout circuit, a 12-bit SAR type ADC, 16 kB RAM, 16 kB ROM and other digital peripherals. The design is implemented in a 0.18 µm CMOS technology and used a die area of 1.52 mm × 3.24 mm. The simulated maximum power consumption of the analog block is 592 µW. The number of external components required by the SoC is limited to an external memory device, sensors, antenna and some passive components. The external memory device contains the application specific firmware. Based on the application, the firmware can be modified accordingly. The SoC design is suitable for medical implants to measure physiological parameters like temperature, pressure or ECG. As an application example, the authors have proposed a bioimplant to measure arterial blood pressure for patients suffering from Peripheral Artery Disease (PAD).
In the past two decades much has been published on whiplash injury, yet both the confusion regarding the condition, and the medicolegal discussion about it have increased. In this paper, functional imaging research results are summarized using MRIcroGL3D visualization software and assembled in an image comprising regions of cerebral activation and deactivation.