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Background: Cardiac resynchronization therapy (CRT) is an established therapy for heart failure (HF) patients (P) with reduced left ventricular (LV) ejection fraction and electrical interventricular desynchronization, but not all P improved clinically. The aim of the study was to evaluate electrical interventricular delay (IVD) to LV delay (LVD) ratio in atrial fibrillation (AF) CRT responder (R) and non-responder (NR).
Methods: AF P (n = 18, age 60.6 ± 11.4 years, 1 female, 17 males) with HF New York Heart Association (NYHA) class 3.0 ± 0.2, 25.3 ± 5.9 % LV ejection fraction and 157.8 ± 24.4 ms QRS duration (QRSD) were measured by surface ECG and focused transesophageal bipolar LV ECG before implantation of CRT pacemaker (n = 2) or CRT defibrillator (n = 16). IVD was measured between onset of QRS in the surface ECG and onset of LV signal in the LV ECG. LVD was measured between onset and offset of LV signal in the LV ECG.
Results: Electrical ventricular desynchronization in AF CRT P were 61.9 ± 26.9ms IVD, 80.6 ± 24.3ms LVD, 0.85 ± 0.41 IVD-LVD-ratio (Figure), 3.12 ± 1.89 QRSD-IVD-ratio and 2.07 ± 0.47 QRSD-LVD-ratio. There were 72.2 % AF CRT R (n = 13) with 64.2 ± 24.6ms IVD and 77.8 ± 21.6ms LVD with Pearson correlation to 0.89 ± 0.39 IVD-LVD-ratio (r = 0.87, P < 0.01; r = -0.69, P < 0.01), 2.82 ± 1.32 QRSD-IVD-ratio (r = -0.76, P < 0.01; r = 0.67, P = 0.011) and 2.13 ± 0.46 QRSD-LVD-ratio (r = 0.57, P = 0.041; r = -0.85, P < 0.01). There were 27.8% AF CRT NR (n = 5) with 56.0 ± 34.5ms IVD and 87.8 ± 31.9ms LVD without correlation to 0.74 ± 0.48 IVD-LVD-ratio, 3.88 ± 2.98 QRSD-IVD-ratio and 1.90 ± 0.48 QRSD-LVD-ratio. During 15.3 ± 13.1 month CRT follow-up, the AF CRT R NYHA class improved from 3.0 ± 0.2 to 2.2 ± 0.3 (P < 0.001). During 18.8 ± 20.7 month CRT follow-up, the AF CRT NR NYHA class not improved from 3 to 3.3 ± 0.97.
The industry of the agave-derived bacanora, in the northern Mexican state of Sonora, has been growing substantially in recent years. However, this higher demand still lies under the influences of a variety of social, legal, cultural, ecological and economic elements. The governmental institutions of the state have tried to encourage a sustainable development and certain levels of standardization in the production of bacanora by applying different economical and legal strategies. However, a large portion of this alcoholic beverage is still produced in a traditional and rudimentary fashion. Beyond the quality of the beverage, the lack of proper control, by using adequate instrumental methods, might represent a health risk, as in several cases traditional-distilled beverages can contain elevated levels of harmful materials. The present article describes the qualitative spectral analysis of samples of the traditional-produced distilled beverage bacanora in the range from 0 cm−1 to 3500 cm−1 by using a Fourier Transform Raman spectrometer. This particular technique has not been previously explored for the analysis of bacanora, as in the case of other beverages, including tequila. The proposed instrumental arrangement for the spectral analysis has been built by combining conventional hardware parts (Michelson interferometer, photo-diodes, visible laser, etc.) and a set of self-developed evaluation algorithms. The resulting spectral information has been compared to those of pure samples of ethanol and to the spectra from different samples of the alcoholic beverage tequila. The proposed instrumental arrangement can be used the analysis of bacanora.
Flexible Three-dimensional Camera-based Reconstruction and Calibration of Tracked Instruments
(2016)
Navigated instruments commonly include applied parts, e.g. burrs or saw blades, that need to be calibrated with respect to the attached or integrated tracker. Since this calibration has to be very precise, it is often performed by the manufacturer. However, due to the great variety of instruments and the option to exchange the applied parts (e.g. burrs) there is a definite demand for flexible and generic calibration techniques. Furthermore, if we look into the medical field, there is also a need for calibrating sterile instruments. We propose a new and flexible camera-based calibration technique that addresses these demands by working contactlessly, precisely, and generically for a large variety of tracked instruments. This is realized using one or more tracked cameras which are calibrated with respect to an attached or integrated tracker. The tracked instrument is rotated in front of the camera(s) and its 3D geometry and surface are reconstructed from the 2D images in the coordinate system of the attached or integrated tracker. The 3D geometry of the navigated instrument was reconstructed with an accuracy of under 0.2 mm. The radius of a sphere-shaped instrument was reconstructed with an RMS deviation of 0.015mm.
Economic dispatch is a well-known optimization problem in smart grid systems which aims at minimizing the total cost of power generation among generation units while maintaining some system constraints. Recently, some distributed consensus-based approaches have been proposed to replace traditional centralized calculation. However, existing approaches fail to protect privacy of individual units like cost function parameters, generator constraints, output power levels, etc. In this paper, we show an attack against an existing consensus-based economic dispatch algorithm from [16] assuming semi-honest non-colluding adversaries. Then we propose a simple solution by combining a secure sum protocol and the consensus-based economic dispatch algorithm that guarantees data privacy under the same attacker model. Our Privacy Preserving Economic Dispatch (PPED) protocol is information-theoretically secure.
The number of impaired persons rises -- as a result of both regular degradation with age and psychological problems like burnout. Sheltered work organizations aim to reintegrate impaired persons into work environments and prepare them for the re-entry in the regular job market.
Both for elderly and for impaired persons it is crucial to quickly assess the abilities, to identify limits and potentials and thus find work processes suitable for their skill profile.
This work focuses on the analysis and comparison of software-tools that assess the abilities of persons with impairments. We describe two established generic tools (CANTAB, Cogstate), analyze a yet unknown specialized tool (Hamet) and present a new gamified tool (GATRAS).
Finally, we present a study with 20 participants with impairments, comparing the tools against a ground truth baseline generated by a real-world assembly task.
A number of design rules must be adhered to in the development and manufacturing of unmanned aerial vehicles. In this, additive manufacturing, particularly in the implementation of requirements with respect to light-weight construction and sustainability, offers several advantages compared to conventional manufacturing methods. Therefore, this article will primarily introduce and compare current concepts for sustainable design using additive manufacturing. These will, above all, consist of the production of complete fuselages and wings by means of rapid prototyping or also rapid tooling. In addition, a new concept will be introduced in which a UAV using AM can be implemented through the combination of very light components and a preferably resource-saving manufacturing method. In this process, a three-dimensional spaceframe is used in combination with a covering in the construction of the wing. Hereby, the development process for sustainable design using additive manufacturing will be analyzed and the results will be explained by means of concrete case studies. In conclusion, the results of these case studies will be compared to the latest technology regarding wing span load.
Due to its numerous application fields and benefits, virtualization has become an interesting and attractive topic in computer and mobile systems, as it promises advantages for security and cost efficiency. However, it may bring additional performance overhead. Recently, CPU virtualization has become more popular for embedded platforms, where the performance overhead is especially critical. In this article, we present the measurements of the performance overhead of the two hypervisors Xen and Jailhouse on ARM processors in the context of the heavy load “Cpuburn-a8” application and compare it to a native Linux system running on ARM processors.