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The visualization of heart rhythm disturbance and atrial fibrillation therapy allow the optimization of new cardiac catheter ablations. With the simulation software CST (Computer Simulation Technology, Darmstadt) electromagnetic and thermal simulations can be carried out to analyze and optimize different heart rhythm disturbance and cardiac catheters for pulmonary vein isolation. Another form of visualization is provided by haptic, three-dimensional print models. These models can be produced using an additive manufacturing method, such as a 3D printer. The aim of the study was to produce a 3D print of the Offenburg heart rhythm model with a representation of an atrial fibrillation ablation procedure to improve the visualization of simulation of cardiac catheter ablation.
The basis of 3D printing was the Offenburg heart rhythm model and the associated simulation of cryoablation of the pulmonary vein. The thermal simulation shows the pulmonary vein isolation of the left inferior pulmonary vein with the cryoballoon catheter Arctic Front AdvanceTM from Medtronic. After running through the simulation, the thermal propagation during the procedure was shown in the form of different colors. The three-dimensional print models were constructed on the base of the described simulation in a CAD program. Four different 3D printers are available for this purpose in a rapid prototyping laboratory at the University of Applied Science Offenburg. Two different printing processes were used: 1. a binder jetting printer with polymer gypsum and 2. a multi-material printer with photopolymer. A final print model with additional representation of the esophagus and internal esophagus catheter was also prepared for printing.
With the help of the thermal simulation results and the subsequent evaluation, it was possible to make a conclusion about the propagation of the cold emanating from the catheter in the myocardium and the surrounding tissue. It could be measured that already 3 mm from the balloon surface into the myocardium the temperature drops to 25 °C. The simulation model was printed using two 3D printing methods. Both methods as well as the different printing materials offer different advantages and disadvantages. While the first model made of polymer gypsum can be produced quickly and cheaply, the second model made of photopolymer takes five times longer and was twice as expensive. On the other hand, the second model offers significantly better properties and was more durable overall. All relevant parts, especially the balloon catheter and the conduction, are realistically represented. Only the thermal propagation in the form of different colors is not shown on this model.
Three-dimensional heart rhythm models as well as virtual simulations allow a very good visualization of complex cardiac rhythm therapy and atrial fibrillation treatment methods. The printed models can be used for optimization and demonstration of cryoballoon catheter ablation in patients with atrial fibrillation.
The visualization of heart rhythm disturbance and atrial fibrillation therapy allows the optimization of new cardiac catheter ablations. With the simulation software CST (Computer Simulation Technology, Darmstadt) electromagnetic and thermal simulations can be carried out to analyze and optimize different heart rhythm disturbance and cardiac catheters for pulmonary vein isolation. Another form of visualization is provided by haptic, three-dimensional print models. These models can be produced using an additive manufacturing method, such as a 3d printer. The aim of the study was to produce a 3d print of the Offenburg heart rhythm model with a representation of an atrial fibrillation ablation procedure to improve the visualization of simulation of cardiac catheter ablation. The basis of 3d printing was the Offenburg heart rhythm model and the associated simulation of cryoablation of the pulmonary vein. The thermal simulation shows the pulmonary vein isolation of the left inferior pulmonary vein with the cryoballoon catheter Arctic Front Advance™ from Medtronic. After running through the simulation, the thermal propagation during the procedure was shown in the form of different colors. The three-dimensional print models were constructed on the base of the described simulation in a CAD program. Four different 3d printers are available for this purpose in a rapid prototyping laboratory at the University of Applied Science Offenburg. Two different printing processes were used and a final print model with additional representation of the esophagus and internal esophagus catheter was also prepared for printing. With the help of the thermal simulation results and the subsequent evaluation, it was possible to draw a conclusion about the propagation of the cold emanating from the catheter in the myocardium and the surrounding tissue. It was measured that just 3 mm from the balloon surface into the myocardium the temperature dropped to 25 °C. The simulation model was printed using two 3d printing methods. Both methods, as well as the different printing materials offer different advantages and disadvantages. All relevant parts, especially the balloon catheter and the conduction, are realistically represented. Only the thermal propagation in the form of different colors is not shown on this model. Three-dimensional heart rhythm models as well as virtual simulations allow very clear visualization of complex cardiac rhythm therapy and atrial fibrillation treatment methods. The printed models can be used for optimization and demonstration of cryoballoon catheter ablation in patients with atrial fibrillation.
The Internet of Things (IoT) application has becoming progressively in-demand, most notably for the embedded devices (ED). However, each device has its own difference in computational capabilities, memory usage, and energy resources in connecting to the Internet by using Wireless Sensor Networks (WSNs). In order for this to be achievable, the WSNs that form the bulk of the IoT implementation requires a new set of technologies and protocol that would have a defined area, in which it addresses. Thus, IPv6 Low Power Area Network (6LoWPAN) was designed by the Internet Engineering Task Force (IETF) as a standard network for ED. Nevertheless, the communication between ED and 6LoWPAN requires appropriate routing protocols for it to achieve the efficient Quality of Service (QoS). Among the protocols of 6LoWPAN network, RPL is considered to be the best protocol, however its Energy Consumption (EC) and Routing Overhead (RO) is considerably high when it is implemented in a large network. Therefore, this paper would propose the HRPL to enchance the RPL protocol in reducing the EC and RO. In this study, the researchers would present the performance of RPL and HRPL in terms of EC, Control traffic Overhead (CTO) and latency based on the simulation of the 6LoWPAN network in fixed environment using COOJA simulator. The results show HRPL protocol achieves better performance in all the tested topology in terms of EC and CTO. However, the latency of HRPL only improves in chain topology compared with RPL. We found that further research is required to study the relationship between the latency and the load of packet transmission in order to optimize the EC usage.
Inadequate mechanical compliance of orthopedic implants can result in excessive strain of the bone interface, and ultimately, aseptic loosening. It is hypothesized that a fiber-based biometal with adjustable anisotropic mechanical properties can reduce interface strain, facilitate continuous remodeling, and improve implant survival under complex loads. The biometal is based on strategically layered sintered titanium fibers. Six different topologies are manufactured. Specimens are tested under compression in three orthogonal axes under 3-point bending and torsion until failure. Biocompatibility testing involves murine osteoblasts. Osseointegration is investigated by micro-computed tomography and histomorphometry after implantation in a metaphyseal trepanation model in sheep. The material demonstrates compressive yield strengths of up to 50 MPa and anisotropy correlating closely with fiber layout. Samples with 75% porosity are both stronger and stiffer than those with 85% porosity. The highest bending modulus is found in samples with parallel fiber orientation, while the highest shear modulus is found in cross-ply layouts. Cell metabolism and morphology indicate uncompromised biocompatibility. Implants demonstrate robust circumferential osseointegration in vivo after 8 weeks. The biometal introduced in this study demonstrates anisotropic mechanical properties similar to bone, and excellent osteoconductivity and feasibility as an orthopedic implant material.
Printed electronics (PE) is a fast-growing field with promising applications in wearables, smart sensors, and smart cards, since it provides mechanical flexibility, and low-cost, on-demand, and customizable fabrication. To secure the operation of these applications, true random number generators (TRNGs) are required to generate unpredictable bits for cryptographic functions and padding. However, since the additive fabrication process of the PE circuits results in high intrinsic variations due to the random dispersion of the printed inks on the substrate, constructing a printed TRNG is challenging. In this article, we exploit the additive customizable fabrication feature of inkjet printing to design a TRNG based on electrolyte-gated field-effect transistors (EGFETs). We also propose a printed resistor tuning flow for the TRNG circuit to mitigate the overall process variation of the TRNG so that the generated bits are mostly based on the random noise in the circuit, providing a true random behavior. The simulation results show that the overall process variation of the TRNGs is mitigated by 110 times, and the generated bitstream of the tuned TRNGs passes the National Institute of Standards and Technology - Statistical Test Suite. For the proof of concept, the proposed TRNG circuit was fabricated and tuned. The characterization results of the tuned TRNGs prove that the TRNGs generate random bitstreams at the supply voltage of down to 0.5 V. Hence, the proposed TRNG design is suitable to secure low-power applications in this domain.
Seismic data has often missing traces due to technical acquisition or economical constraints. A compete dataset is crucial in several processing and inversion techniques. Deep learning algorithms, based on convolutional neural networks (CNNs), have shown alternative solutions that overcome limitation of traditional interpolation methods e.g. data regularity, linearity assumption, etc. There are two different paradigms of CNN methods for seismic interpolation. The first one, so-called deep prior interpolation (DPI), trains a CNN to map random noise to a complete seismic image using only the decimated image itself. The second one, referred as standard deep learning method, trains a CNN to map a decimated seismic image into a complete one using a dataset of complete and artificially decimated images. Within this research, we systematically compare the performance of both methods for different quantities of regular and irregular missing traces using 4 datasets. We evaluate the results of both methods using 5 well-known metrics. We found that DPI method performs better than the standard method if the percentage of missing traces is low (10%) and otherwise if the level of decimation is high (50%).
Radio frequency identification (RFID) antennas are popular for high frequency (HF) RFID, energy transfer and near field communication (NFC) applications. Particularly for wireless measurement systems the RFID/NFC technology is a good option to implement a wireless communication interface. In this context, the design of corresponding reader and transmitter antennas plays a major role for achieving suitable transmission quality. This work proves the feasibility of the rapid prototyping of a RFID/NFC antenna, which is used for the wireless communication and energy harvesting at the required frequency of 13.56 MHz. A novel and low-cost direct ink writing (DIW) technology utilizing highly viscous silver nanoparticle ink is used for this process. This paper describes the development and analysis of low-cost printed flexible RFID/NFC antennas on cost-effective substrates for a microelectronic vital parameter measurement system. Furthermore, we compare the measured technical parameters with existing copper-based counterparts on a FR4 substrate.
The monitoring of industrial environments ensures that highly automated processes run without interruption. However, even if the industrial machines themselves are monitored, the communication lines are currently not continuously monitored in todays installations. They are checked usually only during maintenance intervals or in case of error. In addition, the cables or connected machines usually have to be removed from the system for the duration of the test. To overcome these drawbacks, we have developed and implemented a cost-efficient and continuous signal monitoring of Ethernet-based industrial bus systems. Several methods have been developed to assess the quality of the cable. These methods can be classified to either passive or active. Active methods are not suitable if interruption of the communication is undesired. Passive methods, on the other hand, require oversampling, which calls for expensive hardware. In this paper, a novel passive method combined with undersampling targeting cost-efficient hardware is proposed.
The Go programming language is an increasingly popular language but some of its features lack a formal investigation. This article explains Go's resolution mechanism for overloaded methods and its support for structural subtyping by means of translation from Featherweight Go to a simple target language. The translation employs a form of dictionary passing known from type classes in Haskell and preserves the dynamic behavior of Featherweight Go programs.