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Institute
- Fakultät Elektrotechnik und Informationstechnik (E+I) (bis 03/2019) (234) (remove)
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In der Wertanalyse ist die Methodik TRIZ (Theorie der Lösung erfinderischer Problemstellungen) seit vielen Jahren als Werkzeug zur Kostensenkung oder zur Steigerung der Funktionalität von Produkten bekannt. Seit ihrem ersten Bekanntwerden in Westeuropa hat sich auch TRIZ weiterentwickelt. So wurden Methoden zur Modellierung von Systemen inzwischen erweitert und um Werkzeuge zur schnellen Lösungsfindung, zur Fehlervoraussage und zur Produktplanung neu entwickelt. Durch den weltweiten wissenschaftlichen Fortschritt, die Verwendung unterschiedlicher Sprachen und neue Literatur ist andererseits auch die verwendete Terminologie angewachsen und nicht mehr eindeutig. Die neue VDI-Richtlinie 4521, von deren erstem Teil nun der Gründruck vorliegt, zielt deswegen auf eine Standardisierung der Terminologie und eine vereinheitlichte Beschreibung der Methoden ab. Mit ihrer Hilfe sollen das Studium der Methodik erleichtert, die Benutzung von Literatur vereinfacht und Inhalte der TRIZ klarer darstellbar werden.
In einer Vorlesung nicht abgehängt zu werden und die vielen Ergebnisse strukturiert zu sichern, ist für Studienanfänger eine große Herausforderung. Mitschriebe sind sehr oft unvollständig, unstrukturiert oder „zerfläddert“. Mitschreib-Marathon und Mitdenken schließen sich bei vielen aus. Auch aktivierende Lehrmethoden, Medienwechsel, Lehrvideos führen oft dazu, dass eine strukturierte Sicherung der Inhalte des Lehrgesprächs noch erschwert wird.
Es wird ein Best Practice Beispiel gezeigt, Mathematik-Vorlesungen über ein Tablet-basiertes Mitmach-Skript zu gestalten. Dieses dient als Schrittmacher zwischen Input- und Verarbeitungsphasen und unterstützt die strukturierte Verschriftlichung, indem es Vorteile von Tafel, PPT und klassischem Skript vereint. Traditionelle Methoden werden mit technologischen Möglichkeiten kombiniert, um die angesprochenen Herausforderungen bewusster im Lehrstil zu berücksichtigen. Verbindungen zu Virtual Classroom und Video-gestützter Lehre werden aufgezeigt.
Der Übergang Schule-Studium wird an der Hochschule Offenburg im Vorbereitungskurs Mathematik per Smartphone bzw. Tablet unterstützt. Eine Mathe-App gibt zu den Trainingsaufgaben bei Bedarf Tipps und Teilschritte und hilft so den Studierenden, gemäß individuellem Tempo und Vorkenntnisstand zu arbeiten. Dies fördert eine Aktivierung der Kursteilnehmer auch bei großer Heterogenität. Der mobile Ansatz erlaubt, die ca. 400 Teilnehmer des Präsenz-Kurses in normalen Klassenräumen ohne PC-Ausstattung mit einem eCoach zu unterstützen und ermöglicht die Flexibilisierung von Übungszeit und –Ort über die Präsenzzeit hinaus.
Dieser für die heutige junge Generation attraktive Lernzugang entstand als Kooperationsprojekt zwischen der MassMatics UG und der Hochschule Offenburg. Durch die inhaltliche Orientierung am hochschulübergreifenden Mindestanforderungskatlog Mathematik des cosh-Arbeitskreises entstand eine Lösung, die jedem Studienanfänger zur Vorbereitung auf das Studium nutzen kann (auch ohne Präsenzkurs), die zu den Brückenkurs-Inhalten vieler Hochschulen passt und für die aktuell schon Kooperationsprojekte mit Schulen starten.
Das Projekt MINT-College TIEFE (Talente Individuell, Erfolgreich Fördern und Entwickeln) der Hochschule Offenburg wird im Rahmen des Bund-Länder-Programms Qualitätspakt Lehre aus Mitteln des Bundesministeriums für Bildung und Forschung (BMBF) unter dem Förderkennzeichen 01PL11016 gefördert. Unterstützt wird das Projekt vom Informationszentrum der Hochschule Offenburg.
Virtual-Reality-Darstellung elektromagnetischer Felder in dreidimensionalen Mikrowellenstrukturen
(2000)
Untersuchungen haben gezeigt, daß der Mensch ein Vielfaches an Informationen in Form von visuellen Eindrücken, im Gegensatz zur textuellen Darstellung, verarbeiten kann. Mit Hilfe des numerischen Feld-Simulationsprogramms F3D können Mikrowellenstrukturen auf die Wechselwirkung mit elektromagnetischen Feldern untersucht werden. Das Programm F3D2VRML stellt die Ergebnisse in einer dreidimensionalen Virtual-Reality-Darstellung (VR) dar.
Damit ist es dem Betrachter möglich, mehr Informationen aufzunehmen, da die Informationen mit Formen und Farben im dreidimensionalen Raum visualisiert werden.
Die Einhaltung der innerhalb der Designphase festgelegten Architektur eines Softwareprojektes muss w ̈ahrend der Entwicklungsphase sichergestellt werden. Dieses Papier beschreibt eine Erweiterung des Eclipse-Plugins JDepend4Eclipse, die die Verwaltung von Regels ̈atzen erlaubt und die Pr ̈ufung auf in einem Projekt vorhandene, unerlaubte Abh ̈angigkeiten auf Knopfdruck innerhalb der Entwicklungsumgebung vornimmt. Die Erweiterung des Plugins wird bereits erfolgreich in internen Projekten der Hochschule Offenburg eingesetzt und soll demn ̈achst ̈offentlich verf ̈ugbar sein.
Vergleich der hämodynamischen Reaktion auf VV-Delay Änderungen bei Sinusrhythmus und Vorhofflimmern
(2010)
Das Ausmaß der elektrischen ventrikulären Desynchronisation bei reduzierter linksventrikulärer Funktion ist von Bedeutung für den Erfolg der Resynchronisationstherapie der Herzinsuffizienz mit biventrikulärer Stimulation. Das Ziel der Untersuchung besteht in der nichtinvasiven Messung der elektrischen inter-ventrikulären Desynchronisation mit und ohne ischämische Herzerkrankung bei kardialen Resynchronisationstherapie Respondern. Bei Patienten mit 25,3 ± 7,3 % reduzierter linksventrikulärer Ejektionsfraktion und 166,9 ± 38,5 ms QRS-Dauer wurde das transösophageale linksventrikuläre EKG abgeleitet. Die QRS-Dauer korrelierte mit dem interventrikulären und links-ventrikulären Delay bei Resynchronisationstherapie Respondern mit nicht-ischämischer Herzerkrankung.
Cardiac resynchronization therapy is an established therapy for heart failure patients with sinus rhythm, reduced left ventricular ejection fraction and prolongation of QRS duration. The aim of the study was to evaluate ventricular desynchronization with electrical interventricular delay (IVD) to left ventricular delay (LVD) ratio in atrial fibrillation heart failure patients. IVD and LVD were measured by transesophageal posterior left ventricular ECG recording. In atrial fibrillation heart failure patients with prolonged QRS duration, the mean IVD-to-LVD-ratio was 0.84 +/- 0.42 with a range from 0.17 to 2.2 IVD-to-LVD-ratio. IVD-to-LVD-ratio correlated with QRS duration. IVD-to-LVD-ratio may be a useful parameter to evaluate electrical ventricular desynchronization in atrial fibrillation heart failure patients.
In this paper we propose a motion framework forbipedal robots that decouples motion definitions from stabilizingthe robot. This simplifies motion definitions yet allows dynamicmotion adaptations. Two applications, walking and stopping onone leg, demonstrate the power of the framework. We show thatour framework is able to perform walking and stopping on one legeven under extreme conditions and improves walking benchmarkssignificantly in the RoboCup 3D soccer simulation domain.
Transösophageales interventrikuläres Delay bei Vorhofflimmern und kardialer Resynchronisation
(2013)
Die transösophageale linksventrikuläre Elektrokardiographie ermöglicht die Evaluierung der elektrischen ventrikulären Desynchronisation im Rahmen der kardialen Resynchronisationstherapie der Herzinsuffizienz. Das Ziel der Untersuchung besteht in der präoperativen Abschätzung des transösophagealen interventrikulären Delays bei Vorhofflimmern und kardialer Resynchronisationstherapie. Bei Patienten mit Vorhofflimmern, Herzinsuffizienz New York Heart Association Klasse 3,0 ± 0,2 und QRS-Dauer 159,6 ± 23,9 ms wurde das fokusierte transösophageale linksventrikuläre EKG abgeleitet. Die kardiale Resynchronisationstherapie Responder QRS-Dauer korrelierte mit dem transösophagealen interventrikulären Delay bei Vorhofflimmern.
Transthoracic impedance cardiography (ICG) is a non-invasive method for determination of hemodynamic parameters. The basic principle of transthoracic ICG is the measurement of electrical conductivity of the thorax over the time. The aim of the study was the analysis of hemodynamic parameters from healthy individuals and the evaluation of various hemodynamic monitoring devices. Fourteen men (mean age 25 ± 4.59 years) and twelve women (mean age 24 ± 3.5 years) were measured during the cardiovascular engineering laboratory at Offenburg University of Applied Sciences, Offenburg, Germany. The ICG recordings were measured with the devices CardioScreen 1000, CardioScreen 2000 and TensoScreen with the corresponding Software Cardiovascular Lab 2.5 (Medis Medizinische Messtechnik GmbH, Illmenau, Germany). In order to create identical frame conditions, all measurements were recorded in the same position and for the same duration. Various positions were simulated from horizontal lying position to vertical standing position. Altogether, more than 30 hemodynamic parameters were measured.
The CAN bus still is an important fieldbus in various domains, e.g. for in-car communication or automation applications. To counter security threats and concerns in such scenarios we design, implement, and evaluate the use of an end-to-end security concept based on the Transport Layer Security protocol. It is used to establish authenticated, integrity-checked, and confidential communication channels between field devices connected via CAN. Our performance measurements show that it is possible to use TLS at least for non time-critical applications, as well as for generic embedded networks.
Wireless communication systems more and more become part of our daily live. Especially with the Internet of Things (IoT) the overall connectivity increases rapidly since everyday objects become part of the global network. For this purpose several new wireless protocols have arisen, whereas 6LoWPAN (IPv6 over Low power Wireless Personal Area Networks) can be seen as one of the most important protocols within this sector. Originally designed on top of the IEEE802.15.4 standard it is a subject to various adaptions that will allow to use 6LoWPAN over different technologies; e.g. DECT Ultra Low Energy (ULE). Although this high connectivity offers a lot of new possibilities, there are several requirements and pitfalls coming along with such new systems. With an increasing number of connected devices the interoperability between different providers is one of the biggest challenges, which makes it necessary to verify the functionality and stability of the devices and the network. Therefore testing becomes one of the key components that decides on success or failure of such a system. Although there are several protocol implementations commonly available; e.g., for IoT based systems, there is still a lack of according tools and environments as well as for functional and conformance testing. This article describes the architecture and functioning of the proposed test framework based on Testing and Test Control Notation Version 3 (TTCN-3) for 6LoWPAN over ULE networks.
Nach dem Nachweis der Funktionalität des an der Fachhochschule Offenburg entwickelten Mikroprozessorkernels FHOP (First Homemade Operational Processor), wird eine Anwendung des Kernels in einem Applikationschip beschrieben.
Der Thermologger-ASIC soll mit Hilfe eines Temperatursensors die Umgebungstemperatur bei technischen Prozessen in regelmäßigen Zeitabständen erfassen und abspeichern. Die Meßwerte werden bei Bedarf ber eine serielle Schnittstelle des Thermologger-ASICs an einen PC übertragen und ausgewertet. Zur Verringerung der Leistungsaufnahme wird zwischen zwei Temperaturmessungen in einen Power-Down-Mode geschaltet.
Der ASIC soll später in einer Chipkarte integriert werden.
Die zunehmende Anzahl von Transistoren mit immer kleineren Strukturgrößen führt zu einer zunehmenden Leistungsaufnahme in modernen Prozessoren. Das gilt insbesondere für High-End Prozessoren, die mit einer hohen Taktfrequenz betrieben werden. Die aufgenommene Leistung wird in Wärme umgewandelt, die in einer Temperaturerhöhung der Prozessoren resultiert. Hohe Betriebstemperaturen verursachen u.a. eine verringerte Rechenleistung, eine kürzere Lebensdauer des Prozessors und höhere Leckströme. Aus diesen Gründen wird aktives, dynamisches thermisches Management immer wichtiger. Dieser Beitrag stellt eine Erweiterung zu dem Standard- Linux-Scheduler in der Kernel-Version 3.0 für eingebettete Systeme vor: einen PID-Regler, der unter Angabe einer Solltemperatur eine dynamische Frequenz- und Spannungsskalierung durchführt. Die Experimente auf dem Freescale LMX6 Quadcore-Prozessor zeigen, dass der PID-Regler die Betriebstemperatur des Prozessors an die Solltemperatur regeln kann. Er ist die Grundlage für eine in Zukunft zu entwickelnde prädiktive Regelung.
This paper describes the Sweaty II humanoid adult size robot trying to qualify for the RoboCup 2018 adult size humanoid competition. Sweaty came 2nd in RoboCup 2017 adult size league. The main characteristics of Sweaty are described in the Team Description Paper 2017. The improvements that have been made or are planned to be implemented for RoboCup 2018 are described in this paper.
This paper describes the Sweaty II humanoid adult size robot trying to qualify for the RoboCup 2017 adult size humanoid competition. Sweaty came 2nd in RoboCup 2016 adult size league. The paper describes the main characteristics of Sweaty that made this success possible, and improvements that have been made or are planned to be implemented for RoboCup 2017.
This paper describes the new Sweaty II humanoid adult size robot trying to qualify for the RoboCup 2016 adult size humanoid competition. Based on experiences during RoboCup 2014, the Sweaty robot has been completely redesigned to a new robot Sweaty II. A major change is the use of linear actuators for the legs. Another characteristic is its indirect actuation by means of rods. This allows a variable transmission ratio depending on the angle of a joint.
This paper describes the new Sweaty humanoid adult size robot trying to qualify for the RoboCup 2014 adult size humanoid competition. The robot is built from scratch to eventually allow it to run. One characteristic is that to prevent the motors from overheating, water evaporation is used for cooling. The robot is literally sweating which has given it its name. Another characteristic is, that the motors are not directly connected to the frame but by means of beams. This allows a variable transmission ratio depending on the angle.
The overview of public key infrastructure based security approaches for vehicular communications
(2015)
Modern transport infrastructure becomes a full member of globally connected network. Leading vehicle manufacturers have already triggered development process, output of which will open a new horizon of possibilities for consumers and developers by providing a new communication entity - a car, thus enabling Car2X communications. Nevertheless some of available systems already provide certain possibilities for vehicles to communicate, most of them are considered not sufficiently secured. During last 15 years a number of big research projects funded by European Union and USA governments were started and concluded after which a set of standards were published prescribing a common architecture for Car2X and vehicles onboard communications. This work concentrates on combining inner and outer vehicular communications together with a use of Public Key Infrastructure (PKI).
In this TDP we describe a new tool created for testing the strategy layer of our soccer playing agents. It is a complete 2D simulator that simulates the games based on the decisions of 22 agents. With this tool, debugging the decision and strategy layer of our agents is much more efficient than before due to various interaction methods and complete control over the simulation.
In the future, the tool could also serve as a measure to run simulations of game series much faster than with the 3D simulator. This way, the impact of different play strategies could be evaluated much faster than before.
After having described many different aspects of our team software in previous years, in this paper we take the freedom to describe the magmaChallenge framework provided by the magmaOffenburg team. The framework is used as a benchmark tool to run different challenges like the running challenge in 2014 or the kick accuracy challenge in 2015. This description should serve as a documentation to simplify the maintenance by the community and to add new benchmarks in the future.
This paper describes the magmaOffenburg 3D simulation team trying to qualify for RoboCup 2013. While last year’s TDP focused on different ways how robot behavior can be defined in the magmaOffenburg framework this year we focus on how we statistically evaluate new features on distributed systems. We also show some results gained through such analysis.
This paper describes the magmaOffenburg 3D simulation team trying to qualify for RoboCup 2012. While last year’s TDP focused on the tool set created for 3D simulation and the support for heterogeneous robot models, this year we focus on the different ways how robot behavior can be defined in the magmaOffenburg framework and how those behaviors can be improved by learning.
This paper describes the magmaOffenburg 3D simulation team trying to qualify for RoboCup 2011. While last year’s TDP focused on the tool set created for 3D simulation in this year we describe the further improvement in this tools as well as some new features we implemented focusing on heterogeneous robot models which seem to be used in RoboCup 2012.
An additional tool was written to simply generate situation-dependent strategies. Furthermore some tools, described last year, are now integrated in one single GUI to easy things up.
This paper describes the magmaOffenburg 3D simulation team trying to qualify for RoboCup 2010. While last year’s TDP focused on decisions making using extended behavior networks and on its software architecture and implementation in this year we describe the tool set that was created for RoboCup 3D. It contians a GUI for agent- and world state visualization, for evaluation of localization algorithms and benchmarks in general, a visual editor for Extended Behavior Networks creation and debugging, a live movement tool to interact with the joints and finally a tool for editing behavior motor files.
This paper describes the magmaOffenburg 3D simulation team trying to qualify for RoboCup 2009. It focuses on two distinctive features of the team: decisions making using extended behavior networks and its software architecture and implementation in Java to open the simulation for the Java community.
The Internet of Things (IoT), ubiquitous computing and ubiquitous connectivity, Cyber Physical Systems (CPS), ambient intelligence, Machine-to-Machine communication (M2M) or Car-to-Car (C2C)-communication, smart metering, smart grid, telematics, telecare, telehealth – there are many buzzwords around current developments related to the Internet.
This contribution gives an overview on such IoT-applications, as they are already used today to improve the availability of information, increase efficiency, push system limits and extend the value chain. At a closer look, the economic and technical development can be separated into different phases. It is interesting that we are currently at the threshold to a new phase, with decentralized and cooperative communication and control nodes as cornerstones. Thus, embedded systems and their connectivity are in the middle of the scene.
This recent development is described along with some example projects from the author’s team which are used in industrial automation, energy supply and distribution (home automation and smart metering), traffic engineering (cooperative driver assistance systems), and in telehealth and telecare.
Security in IT systems, particularly in embedded devices like Cyber Physical Systems (CPSs), has become an important matter of concern as it is the prerequisite for ensuring privacy and safety. Among a multitude of existing security measures, the Transport Layer Security (TLS) protocol family offers mature and standardized means for establishing secure communication channels over insecure transport media. In the context of classical IT infrastructure, its security with regard to protocol and implementation attacks has been subject to extensive research. As TLS protocols find their way into embedded environments, we consider the security and robustness of implementations of these protocols specifically in the light of the peculiarities of embedded systems. We present an approach for systematically checking the security and robustness of such implementations using fuzzing techniques and differential testing. In spite of its origin in testing TLS implementations we expect our approach to likewise be applicable to implementations of other cryptographic protocols with moderate efforts.
Tagungsband zum Workshop der Multiprojekt-Chip-Gruppe Baden-Württemberg, Reutlingen, 9. Juli 2010
(2010)
Tagungsband zum Workshop der Multiprojekt-Chip-Gruppe Baden-Württemberg, Künzelsau, 6. Februar 2009
(2009)
Tagungsband zum Workshop der Multiprojekt-Chip-Gruppe Baden-Württemberg, Konstanz, 4. Juli 2008
(2008)
Tagungsband zum Workshop der Multiprojekt-Chip-Gruppe Baden-Württemberg, Karlsruhe, 10. Juli 2009
(2009)
Tagungsband zum Workshop der Multiprojekt-Chip-Gruppe Baden-Württemberg, Göppingen, 5. Februar 2010
(2010)
Gelingt den Studienanfängern eine strukturierte Ergebnissicherung der Lehrveranstaltungen? Oder sind viele allein schon mit einem vollständigen Mitschrieb überfordert? Laufen aktivierende Methoden, Medienwechsel und der Wunsch nach strukturierter Sicherung der Inhalte des Lehrgesprächs teilweise sogar auseinander? Immer mehr Studierende (möchten) auch per Tablet mitschreiben. Wie könnte man in der Lehre auf diese Aspekte stärker eingehen?
Es wird ein praktischer Ansatz gezeigt, Mathematik-Vorlesungen über ein Tablet-basiertes Mitmach-Skript zu gestalten. Dieses dient als Schrittmacher zwischen Input- und Verarbeitungsphasen und unterstützt die strukturierte Verschriftlichung, indem es Vorteile von Tafel, PPT und klassischem Skript vereint. Traditionelle Methoden werden mit technologischen Möglichkeiten kombiniert, um die angesprochenen Herausforderungen bewusster im Lehrstil zu berücksichtigen. Verbindungen zu Virtual Classroom und Video-gestützter Lehre werden aufgezeigt.
Network landscape of recent time contains many different network technologies, a wide range of end-devices with a large scale of capabilities and power, and an immense quantity of information and data represented in different formats. Research on 3D imaging, virtual reality and holographic techniques will result in new user interfaces (UI) for mobile devices, will increase their diversity and variety. In this paper software architecture has been proposed to establish device and content format independent communication including 3D imaging and virtual reality data as content. As experimental validation the concept is implemented in collaborative Language Learning Game (LLG), which is a learning tool for language acquisition.
An der Fachhochschule Offenburg wurde im Sept. 93 das Projekt eines implantierbaren 16 Bit Mikroprozessor-Kernels FHOP ins Leben gerufen. Ausgehend von dem in einem Testchip erfolgreich erprobten umstrukturierten Entwurf wurde durch gezielten Einsatz von strukturiertem Routen unter Nutzung der Fähigkeiten zum hierarchischen Arbeiten in der MENTOR-IC-Station eine erheblich verkleinerte und flächenmäßig optimierte Struktur abgeleitet, die sich mit 4 Quadratmilimetern Fläche durchaus mit kommerziellen Mikroprozessor-Kerneln vergleichen läßt.
Der Entwurf und die Realisierung gedruckter Schaltungen oder Elektronikkomponenten stellt ein intensives Thema der Forschung dar. Forschungsgruppen beschäftigen sich zunehmend mit der Entwicklung von gedruckten Energy Harvestern, weil diese kostengünstig und einfach herstellbar sind. Das Energy Harvesting (EH) oder auch das ”Mikro Energy Harvesting“ (MEH) bezeichnet die Gewinnung von elektrischer Energie aus der Umgebung, um elektronische Verbraucher zu versorgen, kontinuierliche Leistungen zu erzeugen, das System energieeffizienter zu machen, sowie die Energiespeicherung im Mikrowattbereich zu gewährleisten. Energy Harvesting-Systeme stellen eine Alternative gegenüber der Energieversorgung autarker Low-Power-Elektronik mit Batterien dar. Das Energiemanagement solcher EH-Systeme ist jedoch eine Herausforderung aufgrund der Energieverfügbarkeit und der im Zeitablauf nicht konstanten Verlustleistung. Dieser Beitrag gibt einen Überblick über die derzeit existierenden ultra low-power Energiemanagement Schaltungen für Energy Harvester. Dabei wird insbesondere der Fokus auf gedruckte Energy Harvester gelegt. Es soll aufgezeigt werden, welche Aspekte der vorgestellten Energieversorgungsschaltungen bei der Entwicklung eines Energieversorgungschips für gedruckte Energy Harvester berüucksichtigt werden sollen.
Spectral analysis of signal averaging electrocardiography in atrial and ventricular tachyarrhythmias
(2017)
Background: Targeting complex fractionated atrial electrograms detected by automated algorithms during ablation of persistent atrial fibrillation has produced conflicting outcomes in previous electrophysiological studies. The aim of the investigation was to evaluate atrial and ventricular high frequency fractionated electrical signals with signal averaging technique.
Methods: Signal averaging electrocardiography (ECG) allows high resolution ECG technique to eliminate interference noise signals in the recorded ECG. The algorithm uses automatic ECG trigger function for signal averaged transthoracic, transesophageal and intracardiac ECG signals with novel LabVIEW software (National Instruments, Austin, Texas, USA). For spectral analysis we used fast fourier transformation in combination with spectro-temporal mapping and wavelet transformation for evaluation of detailed information about the frequency and intensity of high frequency atrial and ventricular signals.
Results: Spectral-temporal mapping and wavelet transformation of the signal averaged ECG allowed the evaluation of high frequency fractionated atrial signals in patients with atrial fibrillation and high frequency ventricular signals in patients with ventricular tachycardia. The analysis in the time domain evaluated fractionated atrial signals at the end of the signal averaged P-wave and fractionated ventricular signals at the end of the QRS complex. The analysis in the frequency domain evaluated high frequency fractionated atrial signals during the P-wave and high frequency fractionated ventricular signals during QRS complex. The combination of analysis in the time and frequency domain allowed the evaluation of fractionated signals during atrial and ventricular conduction.
Conclusions: Spectral analysis of signal averaging electrocardiography with novel LabVIEW software can utilized to evaluate atrial and ventricular conduction delays in patients with atrial fibrillation and ventricular tachycardia. Complex fractionated atrial electrograms may be useful parameters to evaluate electrical cardiac arrhythmogenic signals in atrial fibrillation ablation.
The formation of secondary phases in the porous electrodes is a severe mechanism affecting the lifetime of solid oxide fuel cells (SOFC). It can occur via various chemical mechanisms and it has a significant influence on cell performance due to pore clogging and deactivation of active surfaces and triple-phase boundary (TPB). We present a modeling and simulation study of nickel oxide formation (reoxidation) and carbon formation (coking) within the SOFC anode. We use a 2D continuum model based on a multi-phase framework [Neidhardt et al., J. Electrochem. Soc., 159, 9 (2012)] that allows the introduction of arbitrary solid phases (here: Ni, YSZ, NiO, Carbon) plus gas phase. Reactions between the bulk phases are modeled via interface-adsorbed species and are described by an elementary kinetic approach. Published experimental data are used for parameterization and validation. Simulations allow the prediction of cell performance under critical operation conditions, like (i) a non-fuel operation test, where NiO formation is taking place (Figure 1a), or (ii) an open circuit voltage (OCV) stability test under hydrocarbon atmosphere, where solid carbon is formed (Figure 1b). Results are applied for enhanced interpretation of experimental data and for prediction of safe operation conditions.
ECG simulators, available on the market, imitate the electric activity of the heart in a simplified manner. Thus, they are suitable for education purposes but not really for testing algorithms to recognize complex arrhythmias needed for pacemakers and implantable defibrillators. Especially certain discrimination between various morphologies of atrial and ventricular fibrillation needs simulators providing native electrograms of different patients’ heart rhythm events. This explains the necessity to develop an ECG simulator providing high-resolution native intracardiac and surface electrograms of in-vivo rhythm events. In this paper we demonstrate an approach for an ECG simulator based on a consumer multichannel soundcard and a corresponding software application for a laptop computer. This Live-ECG Simulator is able to handle invasive electrogram recordings from electrophysiological studies and send the data to a modified external soundcard for subsequent digital to analog conversion. The hardware is completed with an electronic circuit providing level adjustment to adapt the output amplitude to the input conditions of several cardiac implants.
Smoothie: a solution for device and content independent applications including 3D imaging as content
(2014)
Network landscape of recent time contains many different network technologies, a wide range of end-devices with a large scale of capabilities and power, and an immense quantity of information represented in different data formats. Research on 3D imaging, virtual reality and holographic techniques will result in new user interfaces (UI) for mobile devices and will increase their diversity and variety. A lot of effort is being made in order to establish open, scalable and seamless integration of various technologies and content presentation for different devices including those that are mobile, considering the individual situation of the end user. Till today the research is going on in different parts of the world but the task is not completed yet. The goal of this research work is to find a way to solve the above stated problems by investigating system architectures to provide unconstrained, continuous and personalized access to the content and interactive applications everywhere and at anytime with different devices. As a Solution of the problem considered, a new architecture named “Smoothie” is proposed.
Innovative technologies and concepts will emerge as we move towards a more dynamic, service-based, market-driven infrastructure, where energy efficiency and savings can be facilitated by interactive distribution networks. A new generation of fully interactive Information and Communication Technologies (ICT) infrastructure has to be developed to support the optimal exploitation of the changing, complex business processes and to enable the efficient functioning of the deregulated energy market for the benefit of citizens and businesses. The architecture of such distributed system landscapes must be designed and validated, standards need to be created and widely supported, and comprehensive, reliable IT applications will need to be implemented. The collaboration between a smart house and a smart grid is a promising approach which, with the help of ICT can fully unleash the capabilities of the smart electricity network.
The electrical field (E-field) of the biventricular (BV) stimulation is important for the success of cardiac resynchronization therapy (CRT) in patients with cardiac insufficiency and widened QRS complex.
The aim of the study was to model different pacing and ablation electrodes and to integrate them into a heart model for the static and dynamic simulation of BV stimulation and HF ablation in atrial fibrillation (AF).
The modeling and simulation was carried out using the electromagnetic simulation software CST. Five multipolar left ventricular (LV) electrodes, four bipolar right atrial (RA) electrodes, two right ventricular (RV) electrodes and one HF ablation catheter were modelled. A selection were integrated into the heart rhythm model (Schalk, Offenburg) for the electrical field simulation. The simulation of an AV node ablation at CRT was performed with RA, RV and LV electrodes and integrated ablation catheter with an 8 mm gold tip.
The BV stimulation were performed simultaneously at amplitude of 3 V at the LV electrode and 1 V at the RV electrode with a pulse width of 0.5 ms each. The far-field potential at the RA electrode tip was 32.86 mV and 185.97 mV at a distance of 1 mm from the RA electrode tip. AV node ablation was simulated with an applied power of 5 W at 420 kHz at the distal ablation electrode. The temperature at the catheter tip was 103.87 °C after 5 s ablation time and 37.61 °C at a distance of 2 mm inside the myocardium. After 15 s, the temperature was 118.42 °C and 42.13 °C.
Virtual heart and electrode models as well as the simulations of electrical fields and temperature profiles allow the static and dynamic simulation of atrial synchronous BV stimulation and HF ablation at AF and could be used to optimize the CRT and AF ablation.
Cardiac resynchronization therapy with biventricular pacing is an established therapy for heart failure patients with electrical left ventricular desynchronization. The aim of this study was to evaluate left atrial conduction delay, intra left atrial conduction delay, left ventricular conduction delay and intra left ventricular conduction delay in heart failure patients using novel signal averaging transesophageal left heart ECG software.
Methods: 8 heart failure patients with dilated cardiomyopathy (DCM), age 68 ± 9 years, New York Heart Association (NYHA) class 2.9 ± 0.2, 24.8 ± 6.7 % left ventricular ejection fraction, 188.8 ± 15.5 ms QRS duration and 8 heart failure patients with ischaemic cardiomyopathy (ICM), age 67 ± 8 years, NYHA class 2.9 ± 0.3, 32.5 ± 7.4 % left ventricular ejection fraction and 167.6 ± 19.4 ms QRS duration were analysed with transesophageal and transthoracic ECG by Bard LabDuo EP system and novel National Intruments LabView signal averaging ECG software.
Results: The electrical left atrial conduction delay was 71.3 ± 17.6 ms in ICM versus 72.3 ± 12.4 ms in DCM, intra left atrial conduction delay 66.8 ± 8.6 ms in ICM versus 63.4 ± 10.9 ms in DCM and left cardiac AV delay 180.5 ± 32.6 ms in ICM versus 152.4 ± 30.4 ms in DCM. The electrical left ventricular conduction delay was 40.9 ± 7.5 ms in ICM versus 42.6 ± 17 ms in DCM and intra left ventricular conduction delay 105.6 ± 19.3 ms in ICM versus 128.3 ± 24.1 ms in DCM.
Conclusions: Left heart signal averaging ECG can be utilized to analyse left atrial conduction delay, intra left atrial conduction delay, left ventricular conduction delay and intra left ventricular conduction delay to improve patient selection for cardiac resynchronization therapy.
Die in dieser Arbeit vorgestellte Vorgehensweise erlaubt die Ortung von Schienenfahrzeugen in topologischen Karten allein mit Hilfe eines Wirbelstromsensorsystems (WSS). Zur Ortung primär erforderlich ist die Identifizierung des befahrenen Gleises selbst, wofür unterschiedliche in einer Karte gespeicherte Merkmale herangezogen werden sowie der zurückgelegte Weg, der durch Zählen der passierten Schwellen ermittelt wird. Diese Merkmale werden mittels eigens definierter, virtueller Sensoren aus dem Signal des WSS gewonnen und mittels einem Bayes’schen Formalismus mit den Referenzdaten aus der vorliegenden topologischen Karte abgeglichen. Diese auf virtuellen Sensoren basierende Vorgehensweise erlaubt eine Parallelisierung der Sensorsignalverarbeitung und eine flexible Einbindung von Sensoren in das Ortungssystem. Die Möglichkeit, Weichen mit einer Trefferquote von 99% zu detektieren, erlaubt die Verfolgung der Fahrzeugposition über die gesamte Fahrstrecke hinweg, unter alleiniger Verwendung der vom WSS gelieferten Messdaten.
RFID- Frontend ISO 15693
(2008)
Introduction: Radiofrequency ablation allows successful treatment of most supraventricular reentrant and focal tachycardias and an increasing number of ventricular tachycardias. Different catheter tips are used. While AV nodal reentrant tachycardias require catheters with a tip of 4mm length, an 8 mm tip electrodes will be used for atrial flutter. A pulmonary vein isolation will be performed using 4 mm irrigated tip electrodes to achieve larger and deeper lesions. The need of a tubing set and pump for saline transfusion is a disadvantage of this technique. Gold tip electrodes can alternatively be used to produce increases in lesion size. Aim of this study was to compare RF ablation catheters of exactly the same geometry with either platin-iridum or gold tip.
Methods: Gold provides an almost four-fold thermal conductivity compared with platinum-iridium. The Cerablate G flutter (Osypka AG, Rheinfelden-Herten) is a newly designed radiofrequency ablation catheter with an 8 mm gold tip. Its power delivery was compared with the Cerablate flutter of same geometry but platin-iridium tip. Therefore, in-vitro RF ablations were performed using pork meat in a 0.9% saline solution at 37°C temperature. A pulsed volume flow was generated using a pump to simulate the blood flow. Temperature controlled ablations of 60 seconds using 45, 55 and 65°C and a maximum of 70W RF power were performed.
Results: Using the Osypka HAT300smart ablator, cumulative power of 167, 474 and 672W was delivered with gold tip against 121, 227 and 310 W with platin-iridium tip. By the Stockert SmartAblate G4 ablator, 202, 546 and 1075W was delivered with gold tip against 117, 246 and 394W with platin-iridium using 45, 55 and 65°C temperature.
Conclusion: During in-vitro investigations, the gold tip electrodes allowed a in power delivery increase of 117 up to 173%. Thus, gold tips can be used to increase lesion depth and diameter without cooling equipment.
Today's network landscape consists of quite different network technologies, wide range of end-devices with large scale of capabilities and power, and immense quantity of information and data represented in different formats. Research on 3D imaging, virtual reality and holographic techniques will result in new user interfaces (UI) for mobile devices and will increase their diversity and variety. A lot of efforts are being done in order to establish open, scalable and seamless integration of various technologies and content presentation for different devices including mobile considering individual situation of the end user. This is very difficult because various kinds of devices used by different users or in different times/parallel by the same user which are not predictable and have to be recognized by the system in order to identify device capabilities. Not only the devices but also Content and User Interfaces are big issues because they could include different kinds of data format like text, image, audio, video, 3D Virtual Reality data and other upcoming formats. A very suitable and useful example of the use of such a system is mobile learning because of the large amount of varying devices with significantly different features and functionalities. This is true not only to support different learners, e.g. all learners within one learning community, but also to support the same learner using different equipment parallel and/or at different times. Those applications may be significantly enhanced by including virtual reality content presentation. Whatever the purposes are, it is impossible to develop and adapt content for all kind of devices including mobiles individually due to different capabilities of the devices, cost issues and author‘s requirement. A solution should be found to enable the automation of the content adaptation process.
In dieser Arbeit wurde eine USB-Schnittstelle für ein bestehendes Mikrocontroller System FHOP realisiert. Im aktuellen Stand funktioniert das Design zuverlässig in Low Speed Konfiguration. Im Full Speed gibt es noch einige Schwierigkeiten, denn die Kommunikation bricht nach einigen Paket-Transfers zusammen. Durch das Emulieren des Designs auf FPGA wurde die Funktion nachgewiesen. Die nächste Aufgabe wird sein, die Hardware zu optimieren, damit das USB-Modul auch im Full Speed zuverlässig funktioniert. Zusätzlich wird die Software auf der PC Seite optimiert, um höhere Übertragungsraten zu erzielen.
Environmental Monitoring is an attractive application field for Wireless Sensor Network (WSN). Water Level Monitoring helps to increase the efficiency of water distribution and management. In Pakistan, the world’s largest irrigation system covers 90.000 km of channels which needs to be monitored and managed on different levels. Especially the sensor systems for the small distribution channels need to be low energy and low cost. The distribution presents a technical solution for a communication system which is developed in a research project being co-funded by German Academic Exchange Service (DAAD). The communication module is based on IEEE-802.15.4 transceivers which are enhanced through Wake-On-Radio (WOR) to combine low-energy and real-time behavior. On higher layers, IPv6 (6LoWPAN) and corresponding routing protocols like Routing Protocol for Low power and Lossy Networks (RPL) can extend range of the network. The data are stored in a database and can be viewed online via a web interface. Of course, also automatic data analysis can be performed.
Gaps in basic math knowledge are among the biggest obstacles to a successful start in university. Students starting their studies in STEM disciplines display significant diversity, “math anxiety” is a widespread phenomenon, and the transition to a self-determined way of studying presents a huge challenge. Universities offer support measures such as preparatory courses. Over the years, Offenburg University realized that with increased diversity, traditional ways of teaching in front of the class have become inefficient. The majority of the students remained inactive and just listened to the teachers’ explanations and the few active participants’ answers.
Since 2013 our new course concept fosters a shift from teaching to active learning on a large scale, involving several hundred participants of our on-site preparatory math courses. This switch to broad active practicing, however, must go hand in hand with providing individual support for an increasingly diverse student body. Meanwhile students bring along their mobile devices, and the training App TeachMatics serves as a facilitator. The course concept has been very well received by both students and teachers.
In public transportation, the motor pool often consists of various different vehicles bought over a duration of many years. Sometimes, they even differ within one batch bought at the same time. This poses a considerable challenge in the storage and allocation of spare parts, especially in the event of damage to a vehicle. Correctly assigning these parts before the vehicle reaches the workshop could significantly reduce both the downtime and, therefore, the actual costs for companies. In order to achieve this, the current software uses a simple probability calculation. To improve the performance, the data of specific companies was analysed, preprocessed and used with several modelling techniques to classify and, therefore, predict the spare parts to be used in the event of a faulty vehicle. We summarize our experience running through the steps of the Cross Industry Standard Process for Data Mining and compare the performance to the previously used probability. Gradient Boosting Trees turned out to be the best modeling technique for this special case.
Mobile learning (m-learning) can be considered as a new paradigm of e-learning. The developed solution enables the presentation of animations and 3D virtual reality (VR) on mobile devices and is well suited for mobile learning. Difficult relations in physics as well as intricate experiments in optics can be visualised on mobile devices without need for a personal computer. By outsourcing the computational power to a server, the coverage is worldwide.
Optische Navigationssysteme weisen bisher eine eindeutige Trennung zwischen nachverfolgendem Gerät (Tool Tracker) und nachverfolgten Geräten (Tracked Tools) auf. In dieser Arbeit wird ein neues Konzept vorgestellt, dass diese Trennung aufhebt: Jedes Tracked Tool ist gleichzeitig auch Tool Tracker und besteht aus Marker-LEDs sowie mindestens einer Kamera, mit deren Hilfe andere Tracker in Lage und Orientierung nachverfolgt werden können. Bei Verwendung von nur einer Kamera geschieht dies mittels Pose Estimation, ab zwei Kameras werden die Marker-LEDs trianguliert. Diese Arbeit beinhaltet die Vorstellung des neuen Peer-To-Peer-Tracking-Konzepts, einen sehr schnellen Pose-Estimation-Algorithmus für beliebig viele Marker sowie die Klärung der Frage, ob die mit Pose Estimation erreichbare Genauigkeit vergleichbar mit der eines Stereo-Kamera-Systems ist und den Anforderungen an die chirurgische Navigation gerecht wird.
In contrast to conventional aortic valve replacement, the Transcatheter Aortic Valve Implantation (TAVI) is a new highly specialist alternative to surgical valve replacement for patients with symptomatic severe aortic stenosis and high operative risk. The procedure was performed in a minimally invasive way and was introduced at the university heart centre, Freiburg – Bad Krozingen in 2008. The results have been getting better and better over the years. The aim of the investigation is the analysis of electrocardiogram conduction time and the electrocardiography changes recorded hours and days after the procedure depending on artificial heart valve models, which may lead to pacemaker implantation, even the analysis of the effectiveness of treatment.
Special implant connection module was developed to combine full features of two commercial heart rhythm simulators, ARSI-4 and Intersim II, into a master-slave teaching system. Seven workstations were equipped with the Carelink and Homemonitoring remote patient monitoring systems. This combination enables in-vitro training of physicians, nurses and students in pace-maker and defibrillator measurements during implantation and individual programming in the follow-up. Thus, extended sets of arrhythmias and electrode problems can be used to simulate problems and their solutions in a wide range of the clinical routine.
Cardiac resynchronization therapy with atrioventricular and interventricular pacing delay optimized biventricular pacing is an established therapy for heart failure patients with sinus rhythm and reduced left ventricular ejection fraction. The aim of the study was to evaluate atrioventricular and interventricular pacing delay optimization in cardiac resynchroniza-tion therapy by transthoracic impedance cardiography in biventricular pacing with different left ventricular electrode po-sition. In biventricular pacing heart failure patients with lateral, posterolateral and anterolateral left ventricular electrode position, the mean optimal atrioventricular sening delay was 108.6 ± 20.3 ms and the mean optimal interventricular pac-ing delay -12.3 ± 25.9 ms. Transthoracic impedance cardiography may be a useful technique to optimize atrioventricular and interventricular pacing delay in biventricular pacing with different left ventricular electrode position.
Existing approaches solving multi-vehicle pickup and delivery problems with soft time windows typically use common benchmark sets to verify their performance. However, there is a gap from these benchmark sets to real world problems with respect to instance size and problem complexity. In this paper we show that a combination of existing approaches together with improved heuristics is able to deal with the instance sizes and complexity of real world problems. The cost savings potential of the heuristics is compared to human dispatching plans generated from the data of a European carrier.
Den Hauptbestandteil des Operationssystems stellt der Zugriff auf SD-Karten mit dem Dateisystem FAT16 von Microsoft dar. Für die Bedienung wurde ein Kommandozeileninterpreter implementiert. Als Ein- und Ausgabegerät dient ein PC mit einem speziellen Terminalprogramm, welcher über USB mit dem Emulationsboard des SIRIUS Softcores verbunden ist. Das System wird über die Eingabe von Befehlen am Terminal gesteuert.
Der SIRIUS Softcore kann nur vom Flash des Emulationsboards booten. Da das Betriebssystem selbst jedoch auf der SD-Karte gespeichert werden soll, ist ein Basis-Betriebssystem erforderlich, welches im Flash abgelegt ist. Das Basis-Betriebssystem lädt gleich nach dem Start das eigentliche Betriebssystem von der SD-Karte. Falls jedoch keine SD-Karte gesteckt ist, ermöglicht das Basis-Betriebssystem mit einem Kommandozeileninterpreter einige Grundfunktionen.
Cardiac resynchronization therapy (CRT) with biventricular pacing is an established therapy for heart failure (HF) patients (P) with ventricular desynchronization and reduced left ventricular (LV) ejection fraction. The aim of this study was to evaluate electrical right atrial (RA), left atrial (LA), right ventricular (RV) and LV conduction delay with novel telemetric signal averaging electrocardiography (SAECG) in implantable cardioverter defibrillator (ICD) P to better select P for CRT and to improve hemodynamics in cardiac pacing.
Methods: ICD-P (n=8, age 70.8 ± 9.0 years; 2 females, 6 males) with VVI-ICD (n=4), DDD-ICD (n=3) and CRT-ICD (n=1) (Medtronic, Inc., Minneapolis, MN, USA) were analysed with telemetric ECG recording by Medronic programmer 2090, ECG cable 2090AB, PCSU1000 oscilloscope with Pc-Lab2000 software (Velleman®) and novel National Intruments LabView SAECG software.
Results: Electrical RA conduction delay (RACD) was measured between onset and offset of RA deflection in the RAECG. Interatrial conduction delay (IACD) was measured between onset of RA deflection and onset of far-field LA deflection in the RAECG. Interventricular conduction delay (IVCD) was measured between onset of RV deflection in the RVECG and onset of LV deflection in the LVECG. Telemetric SAECG recording was possible in all ICD-P with a mean of 11.7 ± 4.4 SAECG heart beats, 97.6 ± 33.7 ms QRS duration, 81.5 ± 44.6 ms RACD, 62.8 ± 28.4 ms RV conduction delay, 143.7 ± 71.4 ms right cardiac AV delay, 41.5 ms LA conduction delay, 101.6 ms LV conduction delay, 176.8 ms left cardiac AV delay, 53.6 ms IACD and 93 ms IVCD.
Conclusions: Determination of RA, LA, RV and LV conduction delay, IACD, IVCD, right and left cardiac AV delay by telemetric SAECG recording using LabView SAECG technique may be useful parameters of atrial and ventricular desynchronization to improve P selection for CRT and hemodynamics in cardiac pacing.
About 20% of those heart failure patients receiving cardiac resynchronization therapy (CRT) are in atrial fibrillation (AF). Current guidelines apply for patients in sinus rhythm only. Recent studies have shown again, that successful resynchronization is closely linked to a pre-existent ventricular desynchronization. In those studies, the interventricular conduction delay (IVCD) was determined prior to device implantation by ultrasound in patients with sinus rhythm (SR)only. In patients with AF this method ́s use is limited.
To implement left-heart electrogram (LHE) into standard programmers and to simplify IVCD measurement in heart failure patients with AF, LHE was recorded in 11 AF patients with heart failure by Biotronik ICS3000 programmer via a15Hz Butterworth high-pass filter. Therefore, TOslim esophageal electrode (Dr. Osypka GmbH, Rheinfelden, Germany) was perorally applied and fixed in position of maximal left ventricular defection. IVCD was measured between onset of QRS in surface ECG and left ventricular defection (LV) in LHE. In addition, intra-left ventricular conduction delay (ILVCD) was measured as duration of LV in LHE.
In all of the 11 AF patients, desynchronization was quantifiable by LHE. Mean QRS of 162 ± 27ms (120-206ms) was linked with IVCD of 62ms ± 27ms (37-98ms) and ILVCD of 110 ± 20ms (80-144ms), at mean. Correlation between IVCD and QRS was 0.39 (n. s.) with IVCD/QRS ratio of 0.38 ± 0.11 (0.22-0.81).
A 15Hz high-pass filtered LHE feature of the Biotronik ICS3000 programmer is feasible to quantify ventricular dyssynchrony in heart failure patients with AF in order to clearly indicate implantation of CRT systems. As relations between QRS duration, IVCD and ILVCD considerably differ interindividually, the predictive values of IVCD, ILVCD and IVCD/QRS ratio for individual CRT response or non-response shall be identified in follow-up studies.
Non-fluoroscopic Imaging with MRT/CT Image Integration - Catheter Positioning with Double Precision
(2014)
Introduction: When antiarrhythmic drug therapy has failed, different approaches of pulmonary vein isolation are considered a reasonable option in the treatment of atrial fibrillation. It will be performed predominantly by radiofrequency catheter ablation. As the individual anatomy of left atrium and the pulmonary veins differs considerably, accurate visualization of these structures is essential during catheter positioning. Using non-fluoroscopic electroanatomic mapping system with image integration, electroanatomic mapping can be combined with highly detailed anatomical MRT or CT information on complex left atrial structures. This may facilitate catheter navigation during ablation for atrial fibrillation.
Methods: The CARTO XP electroanatomic system was used in a project during biomedical engineering study to practice image integration of anonymized real patients that underwent pulmonary vein isolation by CARTO XP and a MRT/CT procedure. Using the image integration software, MRT or CT images were imported into the CARTO XP system. The next process was segmentation of the acquired images. It involves dividing the images into different regions in order to select the structures of interest. In clinical routine, this segmentation has to be performed before catheter ablation. Then, the segmented images were aligned with the reconstructed electroanatomic maps. This consists of several steps, including selection of the left atrium, scaling of the reconstructed geometry, fusion of the structures using landmarks, and optimization of the integration by adjusting the reconstructed geometry of the left atrium.
Results: In the 3 months lasting period of the project, image integration was trained in 13 patients undergoing catheter ablation for atrial fibrillation. Within this period, time consumption for the process decreased from about 90 minutes at the beginning to about 35 minutes at the end for one patient.
Conclusion: Image integration into non-fluoroscopic electroanatomic map is a sophisticated tool in cardiac radiofrequency catheter ablation. Intensive training is necessary to control the procedure.
Hintergrund: Das elektrische interventrikuläre Delay (IVD) und die Lage der linksventrikulären (LV) Elektrode zum Ort der spätesten LV Erregung sind bei Patienten (P) mit Herzinsuffizienz (HF), reduzierter LV Funktion und breiter QRS Dauer (QRSD) von Bedeutung für den Erfolg der kardialen Resynchronisationstherapie (CRT). Die LV Elektrokardiographie ermöglicht eine Abschätzung des elektrischen IVD. Ziel der Studie besteht in der nicht-invasiven Evaluierung des elektrischen IVD bei Patienten (P) mit Vorhofflimmern (AFib) mit und ohne CRT mit biventrikulärer (BV) Stimulation.
Methoden: Bei 49 HF P mit AFib (Alter 63,9 ± 10,8 Jahre; 43 Männer und 6 Frauen) mit New York Heart Association (NYHA) Klasse 2,9 ± 0,4, LV Ejektionsfraktion 26,03 ± 7,99 % und QRS-Dauer (QRSD) 143,69 ± 35,62 ms wurde das elektrische IVD als Intervall zwischen Beginn des QRS-Komplexes im Oberflächen EKG und Beginn des LV Signals im transösophagealen LV EKG bei 31 HF P mit AFib und bei 18 HF P mit AFib und CRT präoperativ bestimmt. Das fokussierte bipolare LV EKG wurde mittels Osypka TO Sonde mit halbkugelförmigen Elektroden in Höhe des maximalen LV Signals registriert.
Ergebnisse: Bei 31 HF P mit AFib betrugen QRSD 135,48 ± 38,78 ms, IVD 49,55 ± 26,38 ms, QRSD-IVD-Verhältnis 3,12 ± 1,11 und das IVD korrelierte mit der QRSD (r=0,75, P<0,001) und dem QRSD-IVD-Verhältnis (r=-0,67, P<0,001) (Fig.). Bei 18 HF P mit AFib und CRT Defibrillator betrugen QRSD 157,83 ± 24,38 ms, IVD 61,94 ± 26,88 ms, QRSD-IVD-Verhältnis 3,12 ± 1,89 und das IVD korrelierte mit der QRSD (r=0,47, P=0,049) und dem QRSD-IVD-Verhältnis (r=-0,73, P<0,001). Bei 72,2 % CRT Responder (R) (n=13) betrugen QRSD 158,15 ± 22,4 ms, IVD 64,23 ± 24,62 ms, QRSD-IVD-Verhältnis 2,82 ± 1,32 und das IVD korrelierte mit der QRSD (r=0,57, P=0,043) und dem QRSD-IVD-Verhältnis (r=-0,76, P=0,0024). Bei 27,8 % CRT Non-Responder (NR) (n=5) betrugen QRSD 157 ± 31,94 ms, IVD 56 ± 34,52 ms, QRSD-IVD-Verhältnis 3,88 ± 2,98 und das IVD korrelierte nicht mit der QRSD (r=0,33, P=0,591) und dem QRSD-IVD-Verhältnis (r=-0,732, P=0,159). Die CRT R verbesserten sich in der NYHA Klasse von 3 ± 0,2 auf 2,2 ± 0,3 (P<0,001) während 15,3 ± 13,1 Monaten BV Stimulation. Bei 15 CRT NR kam es zu keiner Verbesserung der NYHA Klasse von 3 auf 3,3 ± 0,97 (P=0,529) während 18,8 ± 20,7 Monaten BV Stimulation.
Schlussfolgerungen: Das transösophageale LV EKG ermöglicht bei HF-P mit AFib die nichtinvasive Messung des elektrischen IVD präoperativ vor CRT. IVD und QRSD-IVD-Verhältnis sind möglicherweise einfach anwendbare Parameter zur Vorhersage von CRT R und CRT NR bei P mit AFib.
New frontiers of supraventricular tachycardia and atrial flutter evaluation and catheter ablation
(2012)
Radiofrequency catheter ablation (RFCA) has revolutionized treatment for tachyarrhythmias and has become first-line therapy for some tachycardias. Although developed in the 1980s and widely applied in the 1990s, the technique is still in development. Transesophageal atrial pacing (TAP) can used for initiation and termination of supraventricular tachycardia (SVT).
Methods: The paroxysmal SVT include a wide spectrum of disorders including, in descending order of frequency, atrial flutter, atrioventricular (AV) nodal reentry, Wolff-Parkinson-White syndrome, and atrial tachycardia. While not life-threatening in most cases, they may cause important symptoms, such as palpitations, chest discomfort, breathlessness, anxiety, and syncope, which significantly impair quality of life. Medical therapy has variable efficacy, and most patients are not rendered free of symptoms. Research over the past several decades has revealed fundamental mechanisms involved in the initiation and maintenance of all of these arrhythmias. Knowledge of mechanisms has in turn led to highly effective surgical and catheter-based treatments. The supraventricular arrhythmias and their treatment are described in this report. SVT initiation was analysed with programmed TAP in 49 patients with palpitations (age 47 ± 17 years, 24 females, 25 males).
Results: In comparison to antiarrhythmic drug therapy the radiofrequency catheter ablation in patients suffering from atrial flutter, atrioventricular nodal reentry, atrioventricular reentry and atrial tachycardia is the better choice in most cases. TAP SVT initiation was possible in 23 patients before RFCA. Atrial cycle length of SVT was 320 ± 59 ms. We initiated AV nodal reentrant tachycardia (AVNRT, n=15), atrial tachycardia (AT, n=6) and AV reentrant tachycardia with Kent pathway conduction (AVRT, n=2) before RFCA.
Conclusions: Radiofrequency catheter ablation is a successful and safe method to cure most patients with paroxysmal supraventricular tachycardias. TAP allowed initiation and termination of SVT especially in outpatients.