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Background: Transesophageal left atrial (LA) pacing and transesophageal LA ECG recording are semi-invasive techniques for diagnostic and therapy of supraventricular rhythm disturbance. Cardiac resynchronization therapy (CRT) with right atrial (RA) sensed biventricular pacing is an established therapy for heart failure patients with reduced left ventricular (LV) ejection fraction, sinus rhythm and interventricular electrical desynchronization.
Purpose: The aim of the study was to evaluate electromagnetic and voltage pacing fields of the combination of RA pacing, LA pacing and biventricular pacing in patients with long interatrial and interventricular electrical desynchronization.
Methods: The modelling and electromagnetic simulations of transesophageal LA pacing in combination with RA pacing and biventricular pacing would be staged and analyzed with the CST (Computer Simulation Technology) software. Different electrodes were modelled in order to simulate different types of bipolar pacing in the 3D-CAD Offenburg heart rhythm model: The bipolar Solid S (Biotronik) electrode where modelled for RA pacing and right ventricular (RV) pacing, Attain 4194 (Medtronic) for LV pacing and TO8 (Osypka) multipolar esophageal electrode with hemispheric electrodes for LA pacing.
Results: The pacemaker amplitudes for the electromagnetic pacing simulations were performed with 3 V for RA pacing, 1.5 V for RV pacing, 50 V for LA pacing and 3V for LV pacing with pacing impulse duration of 0.5 ms for RA, RV and LV pacing and 10 ms for LA pacing. The atrioventricular pacing delay after RA pacing was 140 ms. The different pacing modes AAI, VVI, DDD, DDD0V and DDD0D were evaluated for the analysis of the electric pacing field propagation of pacemaker, CRT and LA pacing. The pacing results were compared at minimum (LOW) and maximum (HIGH) parameter settings. While the LOW setting produced fewer tetrahedral and more inaccurate results, the HIGH setting produced many tetrahedral and therefore more accurate results.
Conclusions: The simulation of the combination of transesophageal LA pacing with RA sensed biventricular pacing is possible with the Offenburg heart rhythm model. The new temporary 4-chamber pacing method may be additional useful method in CRT non-responders with long interatrial electrical delay.
Sweaty has already participated four times in RoboCup soccer competitions (Adult Size) and came second three times. While 2016 Sweaty needed a lot of luck to be finalist, 2017 Sweaty was a serious adversary in the preliminary rounds. In 2018 Sweaty showed up in the final with some lack of experience and room for improvements, but not without any chance. This paper describes the intended improvements of the humanoid adult size robot Sweaty in order to qualify for the RoboCup 2019 adult size competition.
Most machine learning methods require careful selection of hyper-parameters in order to train a high performing model with good generalization abilities. Hence, several automatic selection algorithms have been introduced to overcome tedious manual (try and error) tuning of these parameters. Due to its very high sample efficiency, Bayesian Optimization over a Gaussian Processes modeling of the parameter space has become the method of choice. Unfortunately, this approach suffers from a cubic compute complexity due to underlying Cholesky factorization, which makes it very hard to be scaled beyond a small number of sampling steps. In this paper, we present a novel, highly accurate approximation of the underlying Gaussian Process. Reducing its computational complexity from cubic to quadratic allows an efficient strong scaling of Bayesian Optimization while outperforming the previous approach regarding optimization accuracy. First experiments show speedups of a factor of 162 in single node and further speed up by a factor of 5 in a parallel environment.
Printed Electronics is perceived to have a major impact in the fields of smart sensors, Internet of Things and wearables. Especially low power printed technologies such as electrolyte gated field effect transistors (EGFETs) using solution-processed inorganic materials and inkjet printing are very promising in such application domains. In this paper, we discuss a modeling approach to describe the variations of printed devices. Incorporating these models and design flows into our previously developed printed design system allows for robust circuit design. Additionally, we propose a reliability-aware routing solution for printed electronics technology based on the technology constraints in printing crossovers. The proposed methodology was validated on multiple benchmark circuits and can be easily integrated with the design automation tools-set.
Narrowband IoT (NB-IoT) as a radio access technology for the cellular Internet of Things (cIoT) is getting more traction due to attractive system parameters, new proposals in the 3 rd Generation Partnership Project (3GPP) Release 14 for reduced power consumption and ongoing world-wide deployment. As per 3GPP, the low-power and wide-area use cases in 5G specification will be addressed by the early NB-IoT and Long-Term Evolution for Machines (LTE-M) based technologies. Since these cIoT networks will operate in a spatially distributed environment, there are various challenges to be addressed for tests and measurements of these networks. To meet these requirements, unified emulated and field testbeds for NB-IoT-networks were developed and used for extensive performance measurements. This paper analyses the results of these measurements with regard to RF coverage, signal quality, latency, and protocol consistency.
Low latency communication is essential to enable mission-critical machine-type communication (mMTC) use cases in cellular networks. Factory and process automation are major areas that require such low latency communication. In this paper, we investigate the potential of adopting the semi-persistent scheduling (SPS) latency reduction technique in narrowband LTE (NB-LTE) networks and provide a comprehensive performance evaluation. First, we investigate and implement SPS in an open-source network simulator (NS3). We perform simulations with a focus on LTE-M and Narrowband IoT (NB-IoT) systems and evaluate the impact of the SPS technique on the uplink latency of these narrowband systems in real industrial automation scenarios. The performance gain of adopting SPS is analyzed and the results is compared with the legacy dynamic scheduling. Our results show that SPS has the potential to reduce the latency of cellular Internet of Things (cIoT) networks. We believe that SPS can be integrated into LTE-M and NB-IoT systems to support low-latency industrial applications.
The high peak power in comparison to the average transmit power is one of the major long-standing problems in multicarrier modulation and is known as the PAPR (peak to average power ratio) problem. Many PAPR reduction methods have been devised and their comparison is usually based on the complementary cumulative distribution function (CCDF) of the PAPR. While this comparison is straightforward and easy to compute, its relationship with system performance metrics like the (uncoded) BER or the word error rate (WER) for coded systems is considerably more involved. We evaluate the impact of the PAPR on performance metrics like uncoded BER, EVM (error vector magnitude), mutual information and the WER for soft decoding. In this context, we find that system performance is not necessarily degraded by an increasing PAPR. We show that a high number of subcarriers, despite the corresponding high PAPR, is actually not a problem for the system performance and provide a simple explanation for this seemingly counter-intuitive fact.
Recent deep learning based approaches have shown remarkable success on object segmentation tasks. However, there is still room for further improvement. Inspired by generative adversarial networks, we present a generic end-to-end adversarial approach, which can be combined with a wide range of existing semantic segmentation networks to improve their segmentation performance. The key element of our method is to replace the commonly used binary adversarial loss with a high resolution pixel-wise loss. In addition, we train our generator employing stochastic weight averaging fashion, which further enhances the predicted output label maps leading to state-of-the-art results. We show, that this combination of pixel-wise adversarial training and weight averaging leads to significant and consistent gains in segmentation performance, compared to the baseline models.
One of the challenges for autonomous driving in general is to detect objects in the car's camera images. In the Audi Autonomous Driving Cup (AADC), among those objects are other cars, adult and child pedestrians and emergency vehicle lighting. We show that with recent deep learning networks we are able to detect these objects reliably on the limited Hardware of the model cars. Also, the same deep network is used to detect road features like mid lines, stop lines and even complete crossings. Best results are achieved using Faster R-CNN with Inception v2 showing an overall accuracy of 0.84 at 7 Hz.
With the surge in global data consumption with proliferation of Internet of Things (IoT), remote monitoring and control is increasingly becoming popular with a wide range of applications from emergency response in remote regions to monitoring of environmental parameters. Mesh networks are being employed to alleviate a number of issues associated with single-hop communication such as low area coverage, reliability, range and high energy consumption. Low-power Wireless Personal Area Networks (LoWPANs) are being used to help realize and permeate the applicability of IoT. In this paper, we present the design and test of IEEE 802.15.4-compliant smart IoT nodes with multi-hop routing. We first discuss the features of the software stack and design choices in hardware that resulted in high RF output power and then present field test results of different baseline network topologies in both rural and urban settings to demonstrate the deployability and scalability of our solution.
Hintergrund: Die Pulmonalvenenisolation (PVI) mit Hilfe von Kryoballonkathetern ist eine anerkannte Methode zur Behandlung von Vorhofflimmern (AF). Diese Methode bietet eine kürzere Behandlungsdauer als die klassische Therapie durch die Hochfrequenzablation (HF). Ziel dieser Studie war es, verschiedene Kryoballonkatheter, HF-Katheter und Ösophaguskatheter in ein Herzrhythmusmodell zu integrieren und mittels statischer und dynamischer Simulation elektrische und thermische Felder bei PVI unter Vorhofflimmern zu untersuchen.
Methodik: Die Modellierung und Simulation erfolgte mit der elektromagnetischen und thermischen Simulationssoftware CST (CST Darmstadt). Zwei Kryoballons, ein HF-Ablationskatheter und ein Ösophaguskatheter wurden auf der Grundlage der technischen Handbücher der Hersteller Medtronic und Osypka modelliert. Der 23 mm Kryoballon und ein kreisförmiger Mappingkatheter wurden in das Offenburger Herzrhythmusmodell integriert, insbesondere die left inferior pulmonary vein (LIPV) zur Simulation der thermischen Feldausbreitung während einer PVI. Die Simulation einer PVI mit HF-Energie wurde mit dem integrierten HF-Ablationskatheter in der Nähe der LIPV durchgeführt. Der im Herzrhythmusmodell platzierte TO8 Ösophaguskatheter ermöglichte die Ableitung linksatrialer elektrischer Felder bei AF und die Analyse thermischer Felder während PVI.
Ergebnisse: Elektrische Felder konnten bei Sinusrhythmus und AF mit einem AF-Fokus in der LIVP statisch und dynamisch im Herzen und Ösophagus simuliert werden. Bei einer simulierten 20 Sekunden Applikation eines Kryoballon-Katheters bei -50°C wurde eine Temperatur von -24°C in einer Tiefe von 0,5 mm im Myokard gemessen. In einer Tiefe von 1 mm betrug die Temperatur -3°C, bei 2 mm Tiefe 18°C und bei 3 mm Tiefe 29°C. Unter der 15 sekündigen Anwendung eines HF-Katheters mit einer 8-mm-Elektrode und einer Leistung von 5 W bei 420 kHz betrug die Temperatur an der Spitze der Elektrode 110°C. In einer Tiefe von 0,5 mm im Myokard betrug die Temperatur 75°C, in einer Tiefe von 1 mm 58°C, in einer Tiefe von 2 mm 45°C und in einer Tiefe von 3 mm 38°C. Im Ösophagus konnte bei den meisten Simulationen eine konstante Temperatur von 37°C gemessen und die Gefahr einer Ösophagus-Fistel ausgeschlossen werden. Bei Kryoablation der LIPV wurde eine Abkühlung des Ösophagus auf 30°C gemessen.
Schlussfolgerungen: Die Herzrhythmussimulation elektrischer und thermaler Felder ermöglichen mit Anwendung unterschiedlicher Herzkatheter eine statische und dynamische Simulation von PVI durch Kryoablation, HF-Ablation und Temperaturanalyse im Ösophagus. Unter Einbeziehung von MRT- oder CT-Daten können elektrische und thermale Simulationen möglicherweise zur Optimierung von PVIs genutzt werden.
Amongst all the major hazard aspects for the health of people in big conglomerates is the increase of the particulate matter concentration. Traditional systems for particulate matter (PM) monitoring have a great number of drawbacks but the main issues are economical and are related to the installation costs and never ending periodical maintenance expenses. After all there are installations of such systems but their number is limited and having in mind the growth of population, cities and industry areas, there is even a bigger need for more information on air quality because PM changes non-linearly, has a wide range and different sources. In this paper, we propose an approach, based on low-cost sensor nodes, for real-time measuring and obtaining information about the PM concentration. The adoption of that approach allows for a detailed study of the intensities of pollution and its sources. The system power supply is powered by a PV module. The power supply unit is designed using a model-based design that is a new approach to prototyping power-operated electronic devices with guaranteed performance.
This paper describes the concept and some results of the project "Menschen Lernen Maschinelles Lernen" (Humans Learn Machine Learning, ML2) of the University of Applied Sciences Offenburg. It brings together students of different courses of study and practitioners from companies on the subject of Machine Learning. A mixture of blended learning and practical projects ensures a tight coupling of machine learning theory and application. The paper details the phases of ML2 and mentions two successful example projects.
Enabling ultra-low latency is one of the major drivers for the development of future cellular networks to support delay sensitive applications including factory automation, autonomous vehicles and tactile internet. Narrowband Internet of Things (NB-IoT) is a 3 rd Generation Partnership Project (3GPP) Release 13 standardized cellular network currently optimized for massive Machine Type Communication (mMTC). To reduce the latency in cellular networks, 3GPP has proposed some latency reduction techniques that include Semi Persistent Scheduling (SPS) and short Transmission Time Interval (sTTI). In this paper, we investigate the potential of adopting both techniques in NB-IoT networks and provide a comprehensive performance evaluation. We firstly analyze these techniques and then implement them in an open-source network simulator (NS3). Simulations are performed with a focus on Cat-NB1 User Equipment (UE) category to evaluate the uplink user-plane latency. Our results show that SPS and sTTI have the potential to greatly reduce the latency in NB-IoT systems. We believe that both techniques can be integrated into NB-IoT systems to position NB-IoT as a preferred technology for low data rate Ultra-Reliable Low-Latency Communication (URLLC) applications before 5G has been fully rolled out.