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First year Business Administration students tend to regard themselves as “non-computer scientists” and often have a lack of motivation about taking IT courses in general, either because they perceive them as too technical, too difficult or somewhat irrelevant. In an attempt to counteract this perception and increase the levels of engagement and willing attendance to class, we decided to flip the traditional lecture model and develop a new teaching and learning approach for the IT Fundamentals course using an open source Enterprise Resource Planning (ERP) system as the platform from which to draw the various underlying IT concepts and through which the relevant competences can be acquired.
This paper describes the implementation process of this new contextualized learning framework “IT via ERP” and the changes in the didactical methods to support it.
Diese Fallstudien sind im Rahmen der Vorlesung "Integrationsseminar" von Bachelorstudenten/-innen des 5. Semesters an der DHBW Mannheim erarbeitet worden. Es handelt sich bei diesen Fallstudien ausschließlich um Unternehmen, die einen Onlinehandel betreiben. Jede Fallstudie beginnt mit der Beschreibung des Beispielunternehmens, deren Entwicklung und Ausrichtung. Anschließend werden die Marktsituation, sowie die Stärken und Schwächen dargestellt. Die Handlungsempfehlung und das Fazit fassen die Schwerpunkte zusammen und die abschließenden Arbeitsfragen können für eine weitere Bearbeitung verwendet werden.
3D Bin Picking with an innovative powder filled gripper and a torque controlled collaborative robot
(2023)
A new and innovative powder filled gripper concept will be introduced to a process to pick parts out of a box without the use of a camera system which guides the robot to the part. The gripper is a combination of an inflatable skin, and a powder inside. In the unjammed condition, the powder is soft and can adjust to the geometry of the part which will be handled. By applying a vacuum to the inflatable skin, the powder gets jammed and transforms to a solid shaped form in which the gripper was brought before applying the vacuum. This physical principle is used to pick parts. The flexible skin of the gripper adjusts to all kinds of shapes, and therefore, can be used to realize 3D bin picking. With the help of a force controlled robot, the gripper can be pushed with a consistent force on flexible positions depending of the filling level of the box. A Kuka LBR iiwa with joint torque sensors in all of its seven axis’ was used to achieve a constant contact pressure. This is the basic criteria to achieve a robust picking process.
Dieser Beitrag stellt die Möglichkeiten des 3D-Druckes unter der Berücksichtigung von Mensch-Roboter-Kollaborations-Anforderungen dar. Dabei werden die Vorteile mit besonderem Fokus auf die zusätzliche Gestaltungsfreiheit erläutert. Anhand von Beispielen wird der Stand der Technik bereits eingesetzter Sensorik sowie deren Notwendigkeit in Greifsystemen erläutert. Im weiteren Verlauf dieses Beitrags werden allgemeine Verfahren für die additive Verarbeitung von leitfähigen Materialien vorgestellt. Daran angeknüpft sind Beispiele speziell zur 3D-gedruckten Sensorik. Abgerundet wird der Beitrag mit einem Ausblick bezüglich 3D-gedruckter Sensorik in MRK-Greifsystemen.
In 4D printing, an additively manufactured component is given the ability to change its shape or function in an intended and useful manner over time. The technology of 4D printing is still in an early stage of development. Nevertheless, interesting research and initial applications exist in the literature. In this work, a novel methodical approach is presented that helps transfer existing 4D printing research results and knowledge into solving application tasks systematically. Moreover, two different smart materials are analyzed, used, and combined following the presented methodical approach to solving the given task in the form of recovering an object from a poorly accessible space. This is implemented by self-positioning, grabbing, and extracting the target object. The first smart material used to realize these tasks is a shape-memory polymer, while the second is a polymer-based magnetic composite. In addition to the presentation and detailed implementation of the methodical approach, the potentials and behavior of the two smart materials are further examined and narrowed down as a result of the investigation. The results show that the developed methodical approach contributes to moving 4D printing closer toward a viable alternative to existing technologies due to its problem-oriented nature.
Diese Fallstudien sind im Rahmen der Vorlesung "Integrationsseminar" von Bachelorstudenten/-innen des 5. Semesters an der DHBW Mannheim erarbeitet worden.Es handelt sich bei diesen Fallstudien ausschließlich um Unternehmen, die einen Onlinehandel betreiben.Jede Fallstudie beginnt mit der Beschreibung des Beispielunternehmens, deren Entwicklung und Ausrichtung. Anschließend werden die Marktsituation, sowie die Stärken und Schwächen dargestellt. Das Fazit und eine Handlungsempfehlung fassen die Schwerpunkte zusammen und die abschließenden Arbeitsfragen können für eine weitere Bearbeitung verwendet werden.
A benchmark analysis of Long Range (LoRaTM) Communication at 2.45 Ghz for safety applications
(2014)
The demand of wireless solutions in industrial applications increases since the early nineties. This trend is not only ongoing, it is further pushed by developments in the area of software stacks like the latest Bluetooth Low Energy Stack. It is also pushed by new chip-designs and powerful and highly integrated electronic hardware. The acceptance of wireless technologies as a possible solution for industrial applications, has overcome the entry barrier [1]. The first step to see wireless as standard for many industrial applications is almost accomplished. Nevertheless there is nearly none acceptance of wireless technology for Safety applications. One highly challenging and demanding requirement is still unsolved: The aspect safety and robustness. Those topics have been addressed in many cases but always in a similar manner. WirelessHART as an example addresses this topic with redundant so called multiple propagation paths and frequency hopping to handle with interferences and loss of network participants. So far the pure peer to peer link is rarely investigated and there are less safety solutions available. One product called LoRa™ can be seen as one possible solution to address this lack of safety within wireless links. This paper focuses on the safety performance evaluation of a modem-chip-design. The use of diverse and redundant wireless technologies like LoRa can lead to an increase acceptance of wireless in safety applications. Many measurements in real industrial application have been carried out to be able to benchmark the new chip in terms of the safety aspects. The content of this research results can help to raise the level of confidence in wireless. In this paper, the term “safety” is used for data transmission reliability.
The need for the logistics sector to timely respond to the increasing requirements of a globalised and digitalised world relies greatly on the com- petences and skills of its labour force. It becomes therefore essential to reinforce the cooperation between universities and business partners in the logistics and supply chain management fields across the European region and to build a logistics knowledge cluster supported by a communication and collaboration platform to foster continuous learning, skill acquisition and experience sharing anytime anywhere. In this paper we focus on designing the conceptual and technical framework for a communication and collaboration platform with the aim to establish the communication pipelines between the partner institutions, facilitating user interactions and exchange, leading to the creation of new knowledge and innovation in the logistics field. This framework is based on the requirements of the three main stakeholders: students, lecturers and companies, and consists of four functional areas defined according to the platform opera- tional requirements. A working prototype of the platform was developed using the Moodle learning management system and its core tools to determine its applicability and possible enhancement requirements. In the next stages of the project some additional tools like a knowledge base and the integration of the partners’ learning management systems to form the logistics knowledge cluster will be implemented.
A novel Bluetooth Low Energy advertising scan algorithm is presented for hybrid radios that are additionally capable to measure energy on Bluetooth channels, e.g. as they would need to be compliant with IEEE 802.15.4. Scanners applying this algorithm can achieve a low latency whilst consuming only a fraction of the power that existing mechanisms can achieve at a similar latency. Furthermore, the power consumption can scale with the incoming network traffic and in contrast to the existing mechanisms, scanners can operate without any frame loss given ideal network conditions. The algorithm does not require any changes to advertisers, hence, stays compatible with existing devices. Performance evaluated via simulation and experiments on real hardware shows a 37 percent lower power consumption compared to the best existing scan setting while even achieving a slightly lower latency which proves that this algorithm can be used to improve the quality of service of connection-less Bluetooth communication or reduce the connection establishment time of connection-oriented communication.
This paper presents a streaming-based E-Learning environment where closer integration between learning and work is achieved by integrating multimedia services into manufacturing processes. It contains a comprehensive and detailed explanation of the proposed E-Learning streaming framework, especially the adaption of streaming services to mobile environments. We first analyze several scenarios where E-Learning streaming services can be integrated into manufacturing processes. To allow systematic and tailor-made integration, we develop a model and a specification language for E-Learning streaming services and apply the model using practical scenarios from real manufacturing processes. Adaption of multimedia streaming services to mobile devices is discussed based on Synchronized Multimedia Integration Language (SMIL). Last, we comment on the benefits of using E-Learning streaming services as part of manufacturing processes and analyze the acceptance of the developed system. The key components of our E-Learning environment are 1) an xml based streaming service specification language, 2) adaption of multimedia E-Learning services to mobile environments, and 3) Web Services for searching, registration, and creation of E-Learning streaming services.
This paper presents a method for supporting the application of Additive Tooling (AT)-based validation environments in integrated product development. Based on a case study, relevant process steps, activities and possible barriers in the realisation of an injection-moulded product are identified and analysed. The aim of the method is to support the target-oriented application of Additive Tooling to obtain physical prototypes at an early stage and to shorten validation cycles.
In 4D printing an additively manufactured component is given the ability to change its shape or function under the influence of an external stimulus. To achieve this, special smart materials are used that are able to react to external stimuli in a specific way. So far, a number of different stimuli have already been investigated and initial applications have been impressively demonstrated, such as self-folding bodies and simple grippers. However, a methodical specification for the selection of the stimuli and their implementation was not yet in the foreground of the development.
The focus of this work is therefore to develop a methodical approach with which the technology of 4DP can be used in a solution- and application-oriented manner. The developed approach is based on the conventional design methodology for product development to solve given problems in a structured way. This method is extended by specific approaches under consideration of the 4D printing and smart materials.
To illustrate the developed method, it is implemented in practice using a problem definition in the form of an application example. In this example, which represents the recovery of an object from a difficult-to-access environment, the individual functions of positioning, gripping and extraction are implemented using 4D printing. The material extrusion process is used for additive manufacturing of all components of the example. Finally, the functions are successfully tested. The developed approach offers an innovative and methodical approach to systematically solve technical complex problems using 4DP and smart materials.
This paper presents a system that uses a multi-stage AI analysis method for determining the condition and status of bicycle paths using machine learning methods. The approach for analyzing bicycle paths includes three stages of analysis: detection of the road surface, investigation of the condition of the bicycle paths, and identification of substrate characteristics. In this study, we focus on the first stage of the analysis. This approach employs a low-threshold data collection method using smartphone-generated video data for image recognition, in order to automatically capture and classify surface condition and status.
For the analysis convolutional neural networks (CNN) are employed. CNNs have proven to be effective in image recognition tasks and are particularly well-suited for analyzing the surface condition of bicycle paths, as they can identify patterns and features in images. By training the CNN on a large dataset of images with known surface conditions, the network can learn to identify common features and patterns and reliably classify them.
The results of the analysis are then displayed on digital maps and can be utilized in areas such as bicycle logistics, route planning, and maintenance. This can improve safety and comfort for cyclists while promoting cycling as a mode of transportation. It can also assist authorities in maintaining and optimizing bicycle paths, leading to more sustainable and efficient transportation system.
A Nonlinear FEM Model to Calculate Third-Order Harmonic and Intermodulation in TC-SAW Devices
(2018)
Nonlinearities in Temperature Compensated SAW (TC-SAW) devices in the 2 GHz range are investigated using a nonlinear finite element model by simultaneously considering both third-order intermodulation distortion (IMD3)and third harmonic (H3). In the employed perturbation approach, different contributions to the total H3, the direct and indirect contribution, are discussed. H3 and IMD3 measurements were fitted simultaneously using scaling factors for SiO 2 film and Cu electrode nonlinear material tensors in TC-SAW devices. We employ a P-Matrix simulation as intermediate step: Firstly, measurement and nonlinear P-Matrix calculations for finite devices are compared and coefficients of the P-Matrix simulation are determined. The nonlinear tensor data of the different materials involved in periodic nonlinear finite element method (FEM) computations are optimized to fit periodic P-Matrix calculations by introducing scaling factors. Thus, the contribution of different materials to the nonlinear behavior of TC-SAW devices is obtained and the role of materials is discussed.
Many sectors, like finance, medicine, manufacturing, and education, use blockchain applications to profit from the unique bundle of characteristics of this technology. Blockchain technology (BT) promises benefits in trustability, collaboration, organization, identification, credibility, and transparency. In this paper, we conduct an analysis in which we show how open science can benefit from this technology and its properties. For this, we determined the requirements of an open science ecosystem and compared them with the characteristics of BT to prove that the technology suits as an infrastructure. We also review literature and promising blockchain-based projects for open science to describe the current research situation. To this end, we examine the projects in particular for their relevance and contribution to open science and categorize them afterwards according to their primary purpose. Several of them already provide functionalities that can have a positive impact on current research workflows. So, BT offers promising possibilities for its use in science, but why is it then not used on a large-scale in that area? To answer this question, we point out various shortcomings, challenges, unanswered questions, and research potentials that we found in the literature and identified during our analysis. These topics shall serve as starting points for future research to foster the BT for open science and beyond, especially in the long-term.
A Review on Kinetic Energy Harvesting with Focus on 3D Printed Electromagnetic Vibration Harvesters
(2021)
The increasing amount of Internet of Things (IoT) devices and wearables require a reliable energy source. Energy harvesting can power these devices without changing batteries. Three-dimensional printing allows us to manufacture tailored harvesting devices in an easy and fast way. This paper presents the development of hybrid and non-hybrid 3D printed electromagnetic vibration energy harvesters. Various harvesting approaches, their utilised geometry, functional principle, power output and the applied printing processes are shown. The gathered harvesters are analysed, challenges examined and research gaps in the field identified. The advantages and challenges of 3D printing harvesters are discussed. Reported applications and strategies to improve the performance of printed harvesting devices are presented.
Background: Assistive Robotic Arms are designed to assist physically disabled people with daily activities. Existing joysticks and head controls are not applicable for severely disabled people such as people with Locked-in Syndrome. Therefore, eye tracking control is part of ongoing research. The related literature spans many disciplines, creating a heterogeneous field that makes it difficult to gain an overview.
Objectives: This work focuses on ARAs that are controlled by gaze and eye movements. By answering the research questions, this paper provides details on the design of the systems, a comparison of input modalities, methods for measuring the performance of these controls, and an outlook on research areas that gained interest in recent years.
Methods: This review was conducted as outlined in the PRISMA 2020 Statement. After identifying a wide range of approaches in use the authors decided to use the PRISMA-ScR extension for a scoping review to present the results. The identification process was carried out by screening three databases. After the screening process, a snowball search was conducted.
Results: 39 articles and 6 reviews were included in this article. Characteristics related to the system and study design were extracted and presented divided into three groups based on the use of eye tracking.
Conclusion: This paper aims to provide an overview for researchers new to the field by offering insight into eye tracking based robot controllers. We have identified open questions that need to be answered in order to provide people with severe motor function loss with systems that are highly useable and accessible.
In medical applications wireless technologies are not widely spread. Today they are mainly used in non latency-critical applications where reliability can be guaranteed through retransmission protocols and error correction mechanisms. By using retransmission protocols within the disturbed shared wireless channel latency will increase. Therefore retransmission protocols are not sufficient for removing latency-critical wired connections within operating rooms such as foot switches. Todays research aims to improve reliability through the physical characteristics of the wireless channel by using diversity methods and more robust modulation. In this paper an Architecture for building up a reliable network is presented. The Architecture offers the possibility for devices with different reliability, latency and energy consumption requirements to participate. Furthermore reliability, latency and energy consumption are scalable for every single participant.
Decentralized applications (dApp) have proliferated in recent years, but their long-term viability is a topic of debate. However, for dApps to be sustainable, and suitable for integration into a larger service networks, they need to attract users and promise reliable availability. Therefore, assessing their longevity is crucial. Analyzing the utilization trajectory of a service is, however, challenging due to several factors, such as demand spikes, noise, autocorrelation, and non-stationarity. In this study, we employ robust statistical techniques to identify trends in currently popular dApps. Our findings demonstrate that a significant proportion of dApps, across a range of categories, exhibit statistically significant positive overall trends, indicating that success in decentralized computing can be sustainable and transcends specific fields. However, there is also a substantial number of dApps showing negative trends, with a disproportionately high number from the decentralized finance (DeFi) category. Furthermore, a more detailed inspection of time series segments shows a clearly diminishing proportion of positive trends from mid-2021 to the present. In summary, we conclude that the dApp economy might have lost some momentum, and that there is a strong element of uncertainty regarding its future significance.
Voice user interfaces (VUIs) offer an intuitive, fast and convenient way for humans to interact with machines and computers. Yet, whether they’ll be truly successful and find widespread uptake in the near future depends on the user experience (UX) they offer. With this survey-based study (n = 108), we aim to identify the major annoyances German voice assistant users are facing in voice-driven human-computer interactions. The results of our questionnaire show that irritations appear in six categories: privacy issues, unwanted activation, comprehensibility, response quality, conversational design and voice characteristics. Our findings can help identify key areas of work to optimize voice user experience in order to achieve greater adaptation of the technology. In addition, they can provide valuable information for the further development and standardization of voice user experience (VUX) research.
Integrating voice / video communication into business processes can accelerate resolution time, reduce mistakes, and establish a full audit-trail of the interactions. Some VoIP service providers offer website based or plugin based solutions, which are, however, difficult to integrate with other applications. A promising approach to overcome these disadvantages is the development of appropriate Web Services to allow applications interacting with a VoIP system. We propose a generic framework for VoIP applications consisting of an XML-based service specification language and a set of reusable Web Service components. Service providers using the proposed service-oriented architecture can offer to their customers a protocol-neutral Web Service interface, thus enabling the deployment of a general and integrated VoIP solution.
… nicht nur in der Energiewirtschaft, sondern auch im positiven und wahrsten Sinne des Wortes in der Fachgruppe PM Windenergie. In über 40 Jahren GPM wurde immer wieder deutlich, dass Projekte und Programme in Wirtschaft und Gesellschaft nicht nur begleitet, sondern auch aus der GPM heraus mitgestaltet werden. Die Entwicklung und die Ergebnisse der Fachgruppe Windenergie machen dies besonders deutlich.
The paper recommends an approach to estimate effectively the probability of buffer overflow in high-speed communication networks, capable of carrying diverse traffic, including self-similar teletraffic, and supporting diverse levels of quality of service. Simulations with stochastic, long-range dependent self-similar traffic source models are conducted. A new efficient algorithm, based on a variant of the RESTART/LRE method, is developed and applied to accelerate the buffer overflow simulation in a finite buffer single server model under long-range dependent self-similar traffic load with different buffer sizes. Numerical examples and simulation results are shown
Achieving Positive Hospitality Experiences through Technology: Findings from Singapore and Malaysia
(2021)
Customers’ experience is one of the most impactful factors in the tourism industry. Only by offering customers an excellent experience is it possible to build and ensure long-term customer loyalty. In today’s world, technology plays a key role in providing customers with an excellent customer experience. This study has the objective of analyzing how a positive customer experience can be achieved, and which technologies are necessary to ensure this. Results were collected through a literature review, and qualitative interviews with managers of selected hotels, as well as of attractions in Malaysia and Singapore. The analysis of these hotels and attractions is based on a set of criteria to determine the extent of the adoption of the new standards that contribute to positive online customer experiences. As a conclusion, different perspectives are compared, and positive and negative aspects of the use of modern technologies in the tourism industry are specified and discussed.
In this paper we suggest to combine the areas of media streaming services, mobile devices, and manufacturing processes to support monitoring, controlling and supervising production processes in order to achieve high levels of efficiency and environmentally friendly production. It contains a comprehensive and detailed explanation of the proposed E-Learning streaming framework, especially the adaption of streaming services to mobile environments. The key components of our approach are 1) an XML-based streaming service specification language, 2) adaption of multimedia E-Learning services to mobile environments, and 3) a media delivery platform for searching, registration, and creation of streaming services for mobile devices.
The technique of laser ultrasonics perfectly meets the need for noncontact, noninvasive, nondestructive mechanical probing of nanometer- to millimeter-size samples. However, this technique is limited to the excitation of low-amplitude strains, below the threshold for optical damage of the sample. In the context of strain engineering of materials, alternative optical techniques enabling the excitation of high-amplitude strains in a nondestructive optical regime are needed. We introduce here a nondestructive method for laser-shock wave generation based on additive superposition of multiple laser-excited strain waves. This technique enables strain generation up to mechanical failure of a sample at pump laser fluences below optical ablation or melting thresholds. We demonstrate the ability to generate nonlinear surface acoustic waves (SAWs) in Nb-SrTiO3 substrates, with associated strains in the percent range and pressures up to 3 GPa at 1 kHz repetition rate and close to 10 GPa for several hundred shocks. This study paves the way for the investigation of a host of high-strain SAW-induced phenomena, including phase transitions in conventional and quantum materials, plasticity and a myriad of material failure modes, chemistry and other effects in bulk samples, thin layers, and two-dimensional materials.
Various rapid prototyping methods have been available for the production of physical architectural models for a few years. This paper highlights in particular the advantages of 3D printing and Fused Layer Modeling for the production of detailed architectural models. In addition, the current challenges for the creation and transfer of CAAD-data are explained. Furthermore, new methods are being developed in order to improve both the technical and economic boundary conditions for the application of 3DP und FLM. This makes the production of models with very detailed interior rooms possible. The internal details are made visible by dividing the complex overall model into individual models connected by means of an innovative plug-in system. In addition, three case studies are shown in which the developed methods are applied in order to implement detailed architectural models. Finally manufacturing time and costs of the architectural models in the three case studies are compared.
Additive manufacturing is a rapidly growing manufacturing process for which many new processes and materials are currently being developed. The biggest advantage is that almost any shape can be produced, while conventional manufacturing methods reach their limits. Furthermore, a lot of material is saved because the part is created in layers and only as much material is used as necessary. In contrast, in the case of machining processes, it is not uncommon for more than half of the material to be removed and disposed of. Recently, new additive manufacturing processes have been on the market that enables the manufacturing of components using the FDM process with fiber reinforcement. This opens up new possibilities for optimizing components in terms of their strength and at the same time increasing sustainability by reducing materials consumption and waste. Within the scope of this work, different types of test specimens are to be designed, manufactured and examined. The test specimens are tensile specimens, which are used both for standardized tensile tests and for examining a practical component from automotive engineering used in student project. This project is a vehicle designed to compete in the Shell Eco-marathon, one of the world’s largest energy efficiency competitions. The aim is to design a vehicle that covers a certain distance with as little fuel as possible. Accordingly, it is desirable to manufacture the components with the lowest possible weight, while still ensuring the required rigidity. To achieve this, the use of fiber-reinforced 3D-printed parts is particularly suitable due to the high rigidity. In particular, the joining technology for connecting conventionally and additively manufactured components is developed. As a result, the economic efficiency was assessed, and guidelines for the design of components and joining elements were created. In addition, it could be shown that the additive manufacturing of the component could be implemented faster and more sustainably than the previous conventional manufacturing.
The fast and cost-effective manufacturing of tools for thermoforming is an essential requirement to shorten the development time of products. Thus, additive processes are used increasingly in tooling for thermoforming of plastic sheets. However, a disadvantage of many additive methods is that they are highly cost-intensive, since complex systems based on laser technology and expensive metal powders are needed. Therefore, this paper examines how to work with favorable additive methods, e.g. Binder Jetting, to manufacture tools, which provide sufficient strength for thermoforming. The use of comparatively low-priced inkjet technology for the layer construction and a polymer plaster as material can be expected to result in significant cost reductions. Based on a case study using a cowling (engine bonnet) for an Unmanned Aerial Vehicle (UAV), the development of a complex tool for thermoforming is demonstrated. The object in this study is to produce a tool for a complex-shaped component in small numbers and high quality in a short time and at reasonable costs. Within the tooling process, integrated vacuum channels are implemented in additive tooling without the need for additional post-processing (for example, drilling). In addition, special technical challenges, such as the demolding of undercuts or the parting of the tool are explained. All process steps from tool design to the use of the additively manufactured tool are analyzed. Based on the manufacturing of a small series of cowlings for a UAV made of plastic sheets (ABS), it is shown, that the Binder Jetting offers sufficient mechanical and thermal strength for additive tooling. In addition, an economic evaluation of the tool manufacturing and a detailed consideration of the required manufacturing times for the different process steps are carried out. Finally, a comparison is made with conventional and alternative additive methods of tooling.
Advanced Truck Load Firm
(2008)
Financing trade and development sustainably will be crucial for Africa. Enhanced collaboration between multilateral development banks, development finance institutions and ECAs could greatly enhance intra-regional trade. Furthermore, setting up a ‘level playing field’ on the continent will allow governments to make strategic interventions for successful export credits and trade finance solutions, fostering growth through trade. African trade is already showing signs of rebounding from the coronavirus- induced recession. Through concerted, co-operative and continent-wide efforts, drawing on the knowledge and resources of all types of institutions and policy experts, Africa will continue to grow confidently and quickly into its increasingly important role as an engine of economic growth and global trade.
All you need is sleep
(2016)
In 21st century, the century when the humanity hopes to embark on interplanetary travel, we are yet to fully reach an understanding of our very own idiosyncratic terra incognita – the human sleep. Sleep is a highly conserved evolutionary process that constitutes approximately one third of our life, and the lack or inadequate sleep may lead to impairment across multiple cognitive domains (Tononi and Cirelli, 2014; Lim and Dinges, 2010). Sleep deprivation also leads to aberrant brain functioning, immunological and metabolic collapse, and if it is sufficiently prolonged it will ultimately lead to death (Tononi and Cirelli, 2014).
There is increasing evidence of central hyperexcitability in chronic whiplash-associated disorders (cWAD). However, little is known about how an apparently simple cervical spine injury can induce changes in cerebral processes. The present study was designed (1) to validate previous results showing alterations of regional cerebral blood flow (rCBF) in cWAD, (2) to test if central hyperexcitability reflects changes in rCBF upon non-painful stimulation of the neck, and (3) to verify our hypothesis that the missing link in understanding the underlying pathophysiology could be the close interaction between the neck and midbrain structures. For this purpose, alterations of rCBF were explored in a case-control study using H215O positron emission tomography, where each group was exposed to four different conditions, including rest and different levels of non-painful electrical stimulation of the neck. rCBF was found to be elevated in patients with cWAD in the posterior cingulate and precuneus, and decreased in the superior temporal, parahippocampal, and inferior frontal gyri, the thalamus and the insular cortex when compared with rCBF in healthy controls. No differences in rCBF were observed between different levels of electrical stimulation. The alterations in regions directly involved with pain perception and interoceptive processing indicate that cWAD symptoms might be the consequence of a mismatch during the integration of information in brain regions involved in pain processing.
Rubber materials are characterized by a variety of inelasticities such as softening behavior, hysteresis loops and permanent set. In order to calculate the inelastic material behavior, constitutive models, that describe rubber as a homogeneous continuum, have to make use of damping or friction elements.
On the nanoscale, there is no need to adopt such rheological models. Inelastic material behavior can be explained and simulated by a continuous rearrangement of bonds, in particular, the van der Waals interactions, and by the polymer chains transitioning between cis and trans equilibrium torsion angles. The discrete molecular dynamics simulations presented in this paper are performed in an explicit FEM environment using nonlinear but elastic force field potentials. From a structural mechanics point of view, topological changes of the polymer network can be interpreted as a sequence of local material instability problems due to negative tangential bond stiffnesses.
In order to obtain representative results within reasonable computational time, the model is optimized with respect to the number of atoms and the loading velocity. It is shown that by increasing the model size, the stress–strain curves become independent of both the atoms initial state and the strain amplitudes.
The aim of this paper is to identify indicators at country level that could prove useful in improving the effectiveness of fraud detection in European Structural and Investment Funds. We analyse data for 454 funds, belonging to the period 2014-2020, from the 28 countries that were members of the European Union in 2014. Explanatory results suggest the convenience of tracking funds, especially in countries with higher GDP and higher transparency levels, and the lesser relevance of the number of irregularities for countries with higher GDP and those receiving larger funds. Fraud and fraud detection rates in individual funds vary significantly across states. Federal states, such as the Federal Republic of Germany, are comparatively successful in detecting fraud in EU funds.