Open Access

This Book of Abstracts of the ModVal 2025 symposium offers detailed insights into current research trends in the field of modeling and experimental validation of electrochemical energy technologies. The symposium program featured two plenary lectures, four keynote addresses, 36 contributed oral presentations in two parallel sessions, and more than 100 posters.

Although there do exist a few aeroacoustic studies on harmful artificial phenomena related to the usage of non-uniform Cartesian grids in lattice Boltzmann methods (LBM), a thorough quantitative comparison between different categories of grid arrangement is still missing in the literature. In this paper, several established schemes for hierarchical grid refinement in lattice Boltzmann simulations are analyzed with respect to spurious aeroacoustic emissions using a weakly compressible model based on a D3Q19 athermal velocity set. In order to distinguish between various sources of spurious phenomena, we deploy both the classical Bhatnagar–Gross–Krook and other more recent collision models like the hybrid recursive-regularization operator, the latter of which is able to filter out detrimental non-hydrodynamic mode contributions, inherently present in the LBM dynamics. We show by means of various benchmark simulations that a cell-centered approach, either with a linear or uniform explosion procedure, as well as a vertex-centered direct-coupling method, proves to be the most suitable with regards to aeroacoustics, as they produce the least amount of spurious noise. Furthermore, it is demonstrated how simple modifications in the selection of distribution functions to be reconstructed during the communication step between fine and coarse grids affect spurious aeroacoustic artifacts in vertex-centered schemes and can thus be leveraged to positively influence stability and accuracy.

Aircraft ad hoc networks simplify airplane-to-airplane or airplane-to-service station communication. It evolved from MANET and VANET ad-hoc networks. MANET connects mobile networks and VANET for cars. Adhoc networks are popular because they can be built without routers or access points when no network exists. Flights are self-organizing nodes in AANET. This dynamic network requires only two nodes and no specific infrastructure. This method is important for GPS navigation, aircraft–ship communications, and navy signaling. These Ad Hoc networks let aircraft interact with the grounds and service stations to decrease traffic between aircraft. It can also connect with a network radar aircraft to avoid collisions. Planes ad-hoc networks connect planes spontaneously. It is versatile and simple. The aircraft adapts to the situation to make connections; thus, routers or networks are unnecessary. Planes’ fast mobility accelerates network evolution. No infrastructure is needed for aircraft to transmit and relay data. AANET optimizes performance despite restricted bandwidth, power, and processing. This paper describes the AANET network and the recommended solutions to improve airplane performance. It also covers existing methodologies, benefits and cons, and various scholars’ work on the AANET.

In the quest for effective lung cancer treatments, the potential of 3,6-diaminoacridine-9-carbonitrile (DAC) has emerged as a game changer. While DAC's efficacy against glioblastoma is well documented, its role in combating lung cancer has remained largely untapped. This study focuses on CTX-1, exploring its interaction with the pivotal EGFR-TKD protein, a crucial target in lung cancer therapeutics. A meticulous molecular docking analysis revealed that CTX-1 exhibits a noteworthy binding affinity of −7.9 kcal/mol, challenging Erlotinib, a conventional lung cancer medication, which displayed a binding affinity of −7.3 kcal/mol. For a deeper understanding of CTX-1's molecular mechanics, this study employed rigorous 100-ns molecular dynamics simulations, demonstrating CTX-1's remarkable stability in comparison with erlotinib. The Molecular Mechanics Poisson–Boltzmann Surface Area (MM-PBSA) method further corroborated these results, with CTX-1 showing a free binding energy of −105.976 ± 1.916 kJ/mol. The true prowess of CTX-1 was tested against diverse lung cancer cell lines, including A549, Hop-62 and H-1299. CTX-1 not only significantly outperformed erlotinib in anticancer activity but also exhibited a spectrum of therapeutic effects. It effectively diminished cancer cell viability, induced DNA damage, halted cell cycle progression, generated reactive oxygen species (ROS), impaired mitochondrial transmembrane potential, instigated apoptosis and successfully inhibited EGFR-TKD. This study not only underscores the potential of CTX-1 a formidable contender in lung cancer treatment but also marks a paradigm shift in oncological therapeutics, offering new horizons in the fight against this formidable disease.

Carbon plate running shoes (CPRSs) have gained widespread popularity among elite and amateur runners, representing one of the most substantial changes in running gear over the past decade. Compared to elite runners, however, amateurs run at lower speeds and show more diverse running styles. This is a meaningful difference as many previous studies on CPRSs focus either on highly trained male runners and higher speeds or only on a single CPRSs manufacturer. The present study aims at bridging this gap by investigating how CPRSs from four different manufacturers affect running economy in amateurs of both sexes at their individual running speeds. For this purpose, 21 trained amateur triathletes (12 men; 9 women) completed an incremental treadmill test until volitional exhaustion, yielding running speeds at ventilatory thresholds 1 (vVT1) and 2 (vVT2). In a second session, subjects ran five trials of 3 × 3 min (speeds of 90% vVT1, ½ (vVT1 + vVT2), and 100% vVT2), wearing one out of four different pairs of CPRSs or their own preferred non-CPRS shoes in each trial. Our results show that tested CPRS models resulted in a significant reduction in the mean energy cost of transport, compared to the non-CPRS control condition, with Cohen’s d amounting to −1.52 (p = 0.016), 2.31 (p < 0.001), 2.57 (p < 0.001), and 2.80 (p < 0.001), respectively, although effect sizes varied substantially between subjects and running speeds. In conclusion, this study provides evidence that amateur athletes may benefit from various manufacturers’ CPRS models at their typical running speeds to a similar degree as highly trained runners. It is recommended that amateur athletes evaluate a range of CPRSs and select the shoe that elicits the least subjective sensation of fatigue over a testing distance of at least 400–1000 m.