Development of a parallelizable QCM-D array for the mass spectrometric analysis of proteins
- Quarz crystal microbalances allow the monitoring of the adsorption process of mass from a liquid to their surface. The adsorbed mass can be analysed regarding to its protein content using mass spectromety. To ensure the protein identification the results of several measurements can be combined. A high content QCM-D array was developed to allow up to ten measurements parallel. The samples can beQuarz crystal microbalances allow the monitoring of the adsorption process of mass from a liquid to their surface. The adsorbed mass can be analysed regarding to its protein content using mass spectromety. To ensure the protein identification the results of several measurements can be combined. A high content QCM-D array was developed to allow up to ten measurements parallel. The samples can be routed inside the array distributing one sample to several chips. The fluidic parts were prototyped using 3D printing. The assembled array was tight and the sample routing function could be demonstrated. A temperature controller was developed and implemented. The parameters for the PID controller were determined and the controller was shown to be able to keep the temperature constant over long time with high accuracy.…
Document Type: | Master's Thesis |
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Zitierlink: | https://opus.hs-offenburg.de/975 | Bibliografische Angaben |
Title (English): | Development of a parallelizable QCM-D array for the mass spectrometric analysis of proteins |
Author: | Siegfried Hohmann |
Advisor: | Bernd Spangenberg, Gerald Brenner-Weiß, Frank Kirschhöfer |
Year of Publication: | 2015 |
Date of first Publication: | 2015/06/17 |
Date of final exam: | 2015/04/30 |
Publishing Institution: | Hochschule Offenburg |
Granting Institution: | Hochschule Offenburg |
Place of publication: | Offenburg |
Page Number: | II, 43, xlii |
URN: | https://urn:nbn:de:bsz:ofb1-opus4-9751 |
Language: | English | Inhaltliche Informationen |
Institutes: | Fakultät Maschinenbau und Verfahrenstechnik (M+V) |
Institutes: | Abschlussarbeiten / Master-Studiengänge / MPE |
DDC classes: | 600 Technik, Medizin, angewandte Wissenschaften / 620 Ingenieurwissenschaften und Maschinenbau |
GND Keyword: | 3D-Druck; Massenspektrometrie; Proteine; Temperaturregelung |
Tag: | 3D printing; High content measurement; Mass spectrometry; QCM-D Array; Temperature control | Formale Angaben |
Open Access: | Open Access |
Licence (German): | Veröffentlichungsvertrag für Publikationen mit Print on Demand |
SWB-ID: | 165789990X |