Mechanical Properties of the Composite Material consisting of β-TCP and Alginate-Di-Aldehyde-Gelatin Hydrogel and Its Degradation Behavior
- This work aimed to determine the influence of two hydrogels (alginate, alginate-di-aldehyde (ADA)/gelatin) on the mechanical strength of microporous ceramics, which have been loaded with these hydrogels. For this purpose, the compressive strength was determined using a Zwick Z005 universal testing machine. In addition, the degradation behavior according to ISO EN 10993-14 in TRIS buffer pH 5.0 andThis work aimed to determine the influence of two hydrogels (alginate, alginate-di-aldehyde (ADA)/gelatin) on the mechanical strength of microporous ceramics, which have been loaded with these hydrogels. For this purpose, the compressive strength was determined using a Zwick Z005 universal testing machine. In addition, the degradation behavior according to ISO EN 10993-14 in TRIS buffer pH 5.0 and pH 7.4 over 60 days was determined, and its effects on the compressive strength were investigated. The loading was carried out by means of a flow-chamber. The weight of the samples (manufacturer: Robert Mathys Foundation (RMS) and Curasan) in TRIS solutions pH 5 and pH 7 increased within 4 h (mean 48 ± 32 mg) and then remained constant over the experimental period of 60 days. The determination surface roughness showed a decrease in the value for the ceramics incubated in TRIS compared to the untreated ceramics. In addition, an increase in protein concentration in solution was determined for ADA gelatin-loaded ceramics. The macroporous Curasan ceramic exhibited a maximum failure load of 29 ± 9.0 N, whereas the value for the microporous RMS ceramic was 931 ± 223 N. Filling the RMS ceramic with ADA gelatin increased the maximum failure load to 1114 ± 300 N. The Curasan ceramics were too fragile for loading. The maximum failure load decreased for the RMS ceramics to 686.55 ± 170 N by incubation in TRIS pH 7.4 and 651 ± 287 N at pH 5.0.…
Document Type: | Article (reviewed) |
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Zitierlink: | https://opus.hs-offenburg.de/5404 | Bibliografische Angaben |
Title (English): | Mechanical Properties of the Composite Material consisting of β-TCP and Alginate-Di-Aldehyde-Gelatin Hydrogel and Its Degradation Behavior |
Author: | Michael Seidenstuecker, Thomas Schmeichel, Lucas Ritschl, Johannes VinkeStaff MemberORCiDGND, Pia Schilling, Hagen Schmal, Anke Bernstein |
Year of Publication: | 2021 |
Place of publication: | Basel |
Publisher: | MDPI |
Page Number: | 18 |
First Page: | 1 |
Last Page: | 18 |
Article Number: | 1303 |
Parent Title (English): | Materials |
Volume: | 14 |
Issue: | 5 |
ISSN: | 1996-1944 |
DOI: | https://doi.org/10.3390/ma14051303 |
URN: | https://urn:nbn:de:bsz:ofb1-opus4-54040 |
Language: | English | Inhaltliche Informationen |
Institutes: | Fakultät Maschinenbau und Verfahrenstechnik (M+V) |
Institutes: | Bibliografie |
Tag: | ADA-gelatin gels; degradation behavior; fracture strength; mechanical properties; β-TCP | Formale Angaben |
Open Access: | Open Access |
Licence (German): | Creative Commons - CC BY - Namensnennung 4.0 International |