Different impedance cardiographic parameters in atrioventricular and interventricular delay optimized biventricular pacing versus right ventricular pacing
- Introduction: Cardiac resynchronisation therapy (CRT) with atrioventricular (AV) and interventricular (VV) optimized biventricular pacing (BV) is an established therapy for heart failure (HF) patients. The aim of the study was to compare AV and VV delay optimization with cardiac output (CO), cardiac index (CI), contractility index (IC) and acceleration index (ACI) impedance cardiographic (ICG)Introduction: Cardiac resynchronisation therapy (CRT) with atrioventricular (AV) and interventricular (VV) optimized biventricular pacing (BV) is an established therapy for heart failure (HF) patients. The aim of the study was to compare AV and VV delay optimization with cardiac output (CO), cardiac index (CI), contractility index (IC) and acceleration index (ACI) impedance cardiographic (ICG) methods in CRT. Methods: 15 HF patients (age 66 ± 10 years; 2 females, 13 males) in New York Heart Association (NYHA) class 3.1 ± 0.4, left ventricular (LV) ejection fraction 21.3 ± 7.8 % and QRS duration 176.1 ± 31.7 ms underwent AV and VV delay optimization with CO, CI, IC and ACI (Cardioscreen ®, Medis GmbH, Ilmenau, Germany) at different AV and VV delay BV pacing settings versus right ventricular (RV) pacing one day after implantation of a CRT device. Results: Optimal AV delay after atrial sensing was 108.6 ± 20.3 ms (n=14) and optimal AV delay after atrial pacing 190 ± 14.1 ms (n=2) with AV delay range from 80 ms to 200 ms. Optimal VV delay was -12.3 ± 25.9 ms left ventricular before RV pacing. RV versus BV pacing mode resulted in improvement of CO from 3.4 ± 1.2 l/min to 4.4 ± 1.4 l/min (p<0.001), CI from 1.8 ± 0.64 l/min/m² to 2.4 ± 0.78 l/min/m² (p<0.001), IC from 0.028 ± 0.011 1/s to 0.036 ± 0.013 1/s (p<0.001) and ACI from 0.667 ± 0.227 1/s² to 0.834 ± 0.282 1/s² (p<0.002). During 34 ± 26 month BV pacing, the NYHA class improved from 3.1 ± 0.4 to 2.1 ± 0.4 (p<0.001). Conclusion: AV and VV delay optimized BV pacing acutely improve hemodynamic parameters of transthoracic ICG and their NYHA class during long-term follow-up. ICG may be a simple and useful technique to optimize AV and VV delay in CRT.…
Document Type: | Conference Proceeding |
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Conference Type: | Konferenz-Abstract |
Zitierlink: | https://opus.hs-offenburg.de/753 | Bibliografische Angaben |
Title (English): | Different impedance cardiographic parameters in atrioventricular and interventricular delay optimized biventricular pacing versus right ventricular pacing |
Conference: | BMT 2011: Conference of the German Society for Biomedical Engineering / DGBMT Jahrestagung (45. : 27.-30. September 2011 : Freiburg, Deutschland) |
Author: | Matthias HeinkeStaff MemberORCiDGND, Bruno IsmerStaff MemberGND, Helmut Kühnert, Olaf Solbrig, Ralf Surber, Anna Haltenberger, Jürgen Querengässer, Dirk Prochnau, Hans Reiner Figulla |
Date of Publication (online): | 2011/09/30 |
Place of publication: | Berlin, Boston |
Publisher: | Walter de Gruyter |
Page Number: | 1 |
First Page: | 14 |
Parent Title (Multiple languages): | Biomedical Engineering / Biomedizinische Technik |
Volume: | 56 |
Issue: | S1 |
ISSN: | 0013-5585 (Print) |
ISSN: | 1862-278X (Online) |
DOI: | https://doi.org/10.1515/bmt.2011.845 |
Language: | English | Inhaltliche Informationen |
Institutes: | Fakultät Elektrotechnik und Informationstechnik (E+I) (bis 03/2019) |
Institutes: | Bibliografie | Formale Angaben |
Open Access: | Closed Access |
Licence (German): | Urheberrechtlich geschützt |